ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Anti-Inflammatory Effects of AAV-Mediated TIMP-1 Gene Transfer in Hepatic Ischemia-Reperfusion Injury.

    S. Duarte, T. Fujii, G. Lipshutz, R. Busuttil, A. Coito.

    The Dumont-UCLA Transplant Center, Los Angeles.

    Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase1 (TIMP-1) is the…
  • 2016 American Transplant Congress

    Histone Deacetylase-2 Gene Deletion in Mice Mitigates Liver Ischemia/Reperfusion Injury.

    D. Murken,1 D. Aufhauser Jr,1 Z. Wang,2 G. Ge,2 W. Hancock,2,3 M. Levine.1,4

    1Department of Surgery, University of Pennsylvania, Philadelphia, PA; 2Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA; 3Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; 4Department of Surgery, Children's Hospital of Philadelphia, Philadelphia, PA.

    Introduction: Ischemia/reperfusion injury (IRI) causes significant morbidity in liver transplantation and other surgical scenarios. A better understanding of the molecular mechanisms of IRI is required…
  • 2016 American Transplant Congress

    Re-Examining the Role of B-1 Cells in a Murine Model of Renal Ischemia Reperfusion Injury.

    D. Firl,1,2,3 A. Das,1 J. Fung,2 M. Carroll.1

    1Harvard Medical School, Boston; 2Cleveland Clinic Lerner College of Medicine, Cleveland; 3HHMI, Chevy Chase.

    We propose a reexamination of the currently underappreciated role of B-1 cells in IRI. Ischemia reperfusion injury (IRI) is a two phase insult composed of…
  • 2016 American Transplant Congress

    Altruistic Kidney Donation: A Single US Transplant Center Experience.

    A. Aguire-Alarcon,1 M. Lubetzky,1 M. McKinney,1 L. Kayler.2

    1Transplantation, Albert Einstein College of Medicine, Bronx, NY; 2Transplantation, University of Buffalo, Buffalo, NY.

    Background: Altruistic donors (ADs) continue to make rising contributions to the donor pool. Increasing efforts have been made to assess ADs to understand the motivations…
  • 2016 American Transplant Congress

    Altruistic Kidney Donation: From the Donor's Perspetive.

    R. Burge,1 S. Potts,2,3 S. Lundie.4

    1Edinburgh Medical School, University of Edinburgh, Edinburgh, United Kingdom; 2Department of Psychological Medicine, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom; 3Department of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom; 4Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.

    Introduction: Although all living kidney donors are offered yearly reviews post-transplant, the restricted contact time and medical focus limits understanding of the motivations and experiences…
  • 2016 American Transplant Congress

    Markers of Activation of Microvascular Endothelial Cells Predict a Poor Long-Term Graft Outcome in Early Renal Graft Biopsies Displaying Acute Tubular Necrosis.

    Y.-C. Dubois-Xu,1 P. Ahmadpoor,1 A. Corchia,1 D. Buob,2 P. Galichon,1 I. Brochériou,1 C. Suberbielle,3 A. Hertig,1 E. Rondeau.1

    1INSERM UMR_S1155, INSERM, Paris, France; 2Pathology, APHP, Hoptal Tenon, Paris, France; 3HLA Institute, INSERM_S940, Paris, France.

    Acute tubular necrosis (ATN), is a histopathological feature frequently seen in the early post renal transplant biopsies taken from patients with delayed graft function (DGF).…
  • 2016 American Transplant Congress

    Improving Kidney Allocation System with Higher Resolution.

    M. Cusick, J. Friedewald, K. Haarberg, J. Leventhal, A. Tambur.

    Northwestern University, Chicago, IL.

    Purpose: The new kidney allocation system (KAS) was implemented to help identify compatible donors for the most highly sensitized patients. Our experience, as well as…
  • 2016 American Transplant Congress

    Telemedicine to Reduce Readmissions Post Liver Transplant: Compliance and Feasibility Results.

    T. Kaiser,1 P. Kimmel,2 S. Osborn,2 S. Diersing,2 B. Boswell,2 J. Huff,2 J. Garrett,1 N. Anwar,1 S. Shah.1

    1Medicine, University of Cincinnati, Cincinnati, OH; 2Transplant, University of Cincinnati Medical Center, Cincinnati, OH.

    Telemedicine (TM) was added to our care model as a mechanism to reduce readmissions post liver transplant (LTx). Establishing a TM home allows for remote…
  • 2016 American Transplant Congress

    Review of Aborted Hepatectomy of Liver Transplantation in a Single Center Study.

    J. Lee, G. Choi, W. Cho, J.-W. Joh, S.-K. Lee, S.-J. Kim, C. Kwon, J. Park, J. Kim.

    General Surgery, Samsung Medical Center, Seoul, Korea.

    Liver transplantation (LT) has become a popular option for the treatment of endstage hepatic failure. More attention has been given to donor safety, but still…
  • 2016 American Transplant Congress

    Wound Healing Complications in Kidney Transplant Recipients Receiving Everolimus.

    P. Ueno,1 H. Tedesco,1 A. Brigido,1 C. Felipe,1 P. Hannun,1 M. Cristelli,1 W. Aguiar,2 J. Medina-Pestana.1

    1Nephrology Division, Hospital do Rim - UNIFESP, Sao Paulo, Brazil; 2Urology Division, Hospital do Rim, Sao Paulo, Brazil.

    Background: Regimens with de novo everolimus (EVR) are associated with a concentration-dependent incidence of wound healing adverse events (WHAE), but mycophenolate use also is related…
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