Am J Transplant, Volume 16, Suppl 3 Archives - Page 13 of 180 - ATC Abstracts

2016 American Transplant Congress
Common Molecular Features of Human Kidney Transplant Rejection Reflect Mechanistic Sharing Between T Cell-Mediated and Antibody-Mediated Rejection.
J. Venner,^1,2 P. Halloran.²
¹University of Queensland, Brisbane, Australia; ²University of Australia, Edmonton, Canada.
We previously reported the molecular features of human kidney transplant biopsies with T cell-mediated rejection (TCMR) (Am J Transplant 14(11):2565-76) and antibody-mediated rejection (ABMR) (Am…
2016 American Transplant Congress
Characteristics of Compatible Pair Participants in Living Donor Kidney Transplant Exchanges.
F. Weng, T. Grogan, A. Patel, S. Mulgaonkar, M. Morgievich.
Renal & Pancreas Transplant Division, Saint Barnabas Medical Center, Livingston, NJ.
Introduction: Compatible pairs of living kidney donors and their intended recipients are being increasingly entered into living donor kidney transplant (LDKT) exchanges. The characteristics of…
2016 American Transplant Congress
Recovery of eGFR in Both Donors and Recipients After Living Donor Kidney Transplantation.
J. Verbesey, A. Gilbert, A. Li, M. Reissmann, N. Foreman, M. Grafals, B. Javaid, P. Abrams, S. Ghasemian, M. Cooper.
MedStar Georgetown Transplant Institute, Washington, DC.
Purpose: LD kidney donation provides a much needed resource for patients with end stage renal disease. Providing adequate renal mass to the recipient (R) is…
2016 American Transplant Congress
Is It Worth Risking Lives of Multiple Procurement Surgeons to Save One Life in Extreme Weather Conditions?
H. Sharma, I. Al-Hasan, M. Richard, O. Ali, A. Sener, D. Quan, V. Macillister.
Multi Organ Transplantation Unit, London Health Sciences Centre, London, Canada.
Transplant needs highly skilled surgeons and allied medical staff to travel to distant locations on short notices and secure a deceased donor organ that is…
2016 American Transplant Congress
IFN-γ and Contact-Dependent Cytotoxicity Are Rate-Limiting for NK Cells in a Model of Antibody-Mediated Chronic Rejection.
C. Lin,¹ R. Plenter,¹ R. Gill.²
¹Medicine, University of Colorado, Denver, Aurora, CO; ²Surgery, University of Colorado, Denver, Aurora, CO.
BACKGROUND. Natural killer (NK) cells are key components of the innate immune that contribute to acute and chronic graft rejection. After engagement with antibody, NK…
2016 American Transplant Congress
ASC-Deficient Dendritic Cells Exhibit Activation Defects and a Reduced Ability to Stimulate Allogeneic T Cells.
A. Scheinok, A. Shigeoka, S. Kasimsetty, R. Elahimehr, D. McKay.
Medicine, University of California-San Diego, La Jolla, CA.
Donor dendritic cell (DC) activation causes adaptive immune responses that lead to rejection of transplanted allografts. Accumulating data suggest that inflammasome assembly within interstitial DCs…
2016 American Transplant Congress
Bortezomib Impacts Tenascin mRNA in PBMNCs.
E. Bradley, O. Moussa, K. Twombley.
Medical University of South Carolina, Charleston.
Tenascin (TNC) is a gene thought to play a role in the binding of receptors and syndecan binding. Syndecans are signal transmembrane proteins that act…
2016 American Transplant Congress
Impact of Simultaneous Pancreas-Kidney Transplantation versus Kidney Transplant Alone on Patient and Graft Survival in Type 2 Diabetics with Elevated BMI.
S. Singh,^1,2 S. Kim.^1,2,3,4
¹Division of Nephrology, Department of Medicine, University of Toronto, Toronto, Canada; ²Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; ³Division of Nephrology and the Multi-Organ Transplant Program, University Health Network, Toronto General Hospital, Toronto, Canada; ⁴Division of Nephrology and the Kidney Transplant Program, St. Michael's Hospital, Toronto, Canada.
Background: Simultaneous Pancreas-Kidney transplantation (SPKT) is becoming increasingly common in patients with Type 2 diabetes (T2DM). The BMI threshold for listing for SPKT in this…
2016 American Transplant Congress
Injurious Procoagulant Pathways During Prolonged Cold Storage of the Donor Pancreas.
B. Sandhu, S. Charitidou, N. Vallant, A. McLean, D. Taube, P. DiCocco, P. Herbert, J. Crane, V. Papalois.
West London Renal and Transplant Centre, London, United Kingdom.
Background: Analyses of pancreas transplant outcomes have revealed that pancreatic grafts exhibit an enhanced intolerance to prolonged cold ischaemia time (CIT), however the underlying pathophysiology…
2016 American Transplant Congress
Vascular Composite Allotransplantation Collaborative Initiative Biobank: Bringing the Power Back to Research.
J. Cheeseman, M.-B. Joshi, F. Leopardi, R. Osborne, D. Conlon, L. Stempora, M. Song, L. Cendales.
Surgery, Duke University, Durham, NC.
Refining Vascular Composite Allotransplantation (VCA) into a useful therapeutic option for patients in need of tissue reconstruction depends on the availability of biological specimens and…