Am J Transplant, Volume 16, Suppl 3 Archives - Page 13 of 180 - ATC Abstracts

2016 American Transplant Congress
Everolimus versus Mycophenolate Mofetil in Combination with Tacrolimus: A Propensity Score Matching Analysis in Liver Transplantation.
P. de Simone,¹ P. Carrai,¹ A. Precisi,² L. Coletti,¹ D. Ghinolfi,¹ F. Filipponi.¹
¹Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospitals, Pisa, Italy; ²Laboratory, University of Pisa Medical School Hospital, Pisa, Italy.
Background: No trial has so far investigated everolimus (EVR)-incorporating immunosuppressive regimens versus combined use of tacrolimus (TAC) and mycophenolate mofetil (MMF) in liver transplantation (LT).Materials…
2016 American Transplant Congress
African-American Primary Renal Transplant Recipients Are at a Significantly Higher Risk to Develop De Novo DSA.
M. Everly,¹ L. Rebellato,² C. Haisch,² K. Briley,² P. Bolin,² S. Kendrick,³ C. Morgan,² A. Maldonado,⁴ A. Nguyen,¹ P. Terasaki.¹
¹Terasaki Foundation Laboratory, Los Angeles; ²East Carolina University, Greenville, NC; ³Eastern Nephrology Associates, Greenville, NC; ⁴Vidant Medical Center, Greenville, NC.
Recent studies have shown multiple risk factors for de novo DSA (dnDSA) development. One controversial risk factor is race. Studying a primarily African-American (AA) transplant…
2016 American Transplant Congress
Kidney Retransplantation Is Associated with Higher Mortality Risk Among HIV+ vs. HIV- Recipients.
B. Shelton,¹ S. Mehta,¹ D. Sawinski,² R. Reed,¹ P. MacLennan,¹ S. Gustafson,³ C. Durand,⁴ D. Segev,⁴ J. Locke.¹
¹School of Medicine, University of Alabama at Birmingham, Birmingham, AL; ²School of Medicine, University of Pennsylvania, Philadelphia, PA; ³Scientific Registry of Transplant Recipients, Minneapolis, MN; ⁴School of Medicine, Johns Hopkins University, Baltimore, MD.
Background: Excellent outcomes have been demonstrated in HIV+ kidney transplant (KT) recipients, yet no study has explored outcomes among HIV+ reKT recipients.Methods: 4,683 adult reKT…
2016 American Transplant Congress
Modification of DC Phenotype and Function via Targeted Porous Silicon Nanoparticles.
S. Stead,¹ S. McInnes,² S. Kireta,³ P. Rose,¹ D. Rojas-Canales,³ S. Jesudason,³ S. Grey,⁴ R. Carroll,³ N. Voelcker,² P. Coates.^1,3
¹School of Medicine, University of Adelaide, Adelaide, Australia; ²Future Industries Institute, University of South Australia, Adelaide, Australia; ³CNARTS, Royal Adelaide Hospital, Adealide, Australia; ⁴Transplantation Immunology, Garvan Institute of Medical Research, Sydney, Australia.
Aims: Dendritic cells (DC) are the most potent antigen-presenting cell and are fundamental in the establishment of transplant tolerance. Targeting DC via the DC-SIGN receptor…
2016 American Transplant Congress
Three-Year Graft Loss Risk in Kidney Transplants: Dynamic Patient Level Data Improve Predictive Efficacy.
T. Srinivas, J. Zhang, Z. Su, D. Taber, J. Marsden, K. Reilly, D. Northrup, J. Long, L. Lenert, W. Moran, P. Mauldin.
MUSC, Charleston, SC.
Background: Predictive models in kidney transplantation using national data (UNOS, SRTR) lack longitudinal patient level data, limiting accuracy. Adding patient level data capturing dynamic clinical…
2016 American Transplant Congress
Outcomes Associated with Carbapenem-Resistant Enterobacteriaceae Infection After Solid Organ Transplantation in a Multicenter Study.
S. Huprikar,¹ L. Casner,¹ L. Camera Pierrotti,² A. Nellore,³ R. Madan,⁴ J. Garcia-Diaz,⁵ S. Jacobs,⁶ D. Lee,⁷ W. Trindade Clemente,⁸ G. Alangaden,⁹ R. La Hoz,¹⁰ N. Theodoropoulos,¹¹ M. Miceli,¹² G. Santoro-Lopes,¹³ D. Banach,¹⁴ D. Simon,¹⁵ G. Patel.¹
¹Mount Sinai, New York; ²Univ of Sao Paulo, Sao Paulo, Brazil; ³UAB, Birmingham; ⁴Albert Einstein, Bronx; ⁵Oschner, New Orleans; ⁶Cornell, New York; ⁷Drexel, Philadelphia; ⁸Univ Federal de Minas Gerais, Belo Horizonte, Brazil; ⁹Henry Ford, Detroit; ¹⁰UT Southwestern, Dallas; ¹¹Ohio State, Columbus; ¹²U of Michigan, Ann Arbor; ¹³Federal Univ of Rio de Janeiro, Rio de Janeiro, Brazil; ¹⁴Yale, New Haven; ¹⁵Rush, Chicago.
BackgroundCarbapenem-resistant Enterobacteriaceae infection (CREI) is associated with poor outcomes in solid organ transplant (SOT) recipients but most reports are single center experiences.MethodsPatients who underwent SOT…
2016 American Transplant Congress
Short-Term Post-Donation Renal Function in Living Kidney Donors.
L. Fahmy, A. Massie, A. Muzaale, S. Sandal, E. Chow, D. Segev.
JHU, Baltimore.
Previous single-center studies of post-donation estimated glomerular filtration rate (eGFR) in living kidney donors were limited by small sample size and lack of generalizability. The…
2016 American Transplant Congress
Utilization and Post-Transplant Outcomes Associated with Hepatitis C+ Donor Kidneys in the Advent of Direct-Acting Antivirals.
M. Bowring, L. Kucirka, A. Massie, X. Luo, M. Sulkowski, D. Segev, C. Durand.
JHU, Baltimore.
The introduction of interferon-free direct-acting antivirals(DAAs) in December 2013 dramatically improved outcomes for individuals with Hepatitis C. The impacts of these therapies on utilization and…
2016 American Transplant Congress
C1-Inhibitor in Acute Antibody-Mediated Rejection Non-Responsive to Conventional Therapy in Kidney Transplant Recipients: A Pilot Study.
C. Lefaucheur,¹ D. Viglietti,¹ C. Gosset,¹ A. Loupy,² A. Zeevi,³ D. Glotz.¹
¹Saint-Louis Hospital, Paris, France; ²Necker Hospital, Paris, France; ³University of Pittsburgh Medical Center, Pittsburgh.
The use of complement inhibitors in the treatment of acute antibody-mediated rejection (AMR) has not been thoroughly evaluated. We performed a prospective, single-arm, pilot study…
2016 American Transplant Congress
Improved Health Related Quality of Life Also in Older Recipients Following Kidney Transplantation.
K. Lønning,¹ K. Heldal,^2,3 T. Bernklev,^2,3 M. Andersen,^1,4 A. Hartmann,^1,3 N. Von der Lippe,³ A. Reisæter,¹ K. Midtvedt.¹
¹Department of Organ Transplantation, Oslo University Hospital, Oslo, Norway; ²Clinic of Internal Medicine, Telemark Hospital, Skien, Norway; ³Institute of Clinical Medicine, University of Oslo, Oslo, Norway; ⁴Department of Health Sciences, University of Oslo, Oslo, Norway.
Background: There is a lack of knowledge regarding elderly patients with end stage renal disease (ESRD) and health related quality of life (HRQOL) after KTX.…