2016 American Transplant Congress
Soluble ST2 and Cardiovascular (CV) Outcomes and Mortality in Kidney Transplant Candidates.
1Mayo Clinic, Phoenix, AZ; 2Mayo Clinic, Rochester, MN.
Introduction: Soluble ST2(sST2), involved in T-cell mediated inflammation and cardiac fibrosis, is a better predictor of cardiovascular events(CVE) in heart failure(HF) and is less affected…2016 American Transplant Congress
Impact of Left Ventricular Diastolic Dysfunction on Patients Being Evaluated for Liver Transplantation.
IntroductionDiastolic dysfunction (DD) is the cardinal finding in cirrhotic cardiomyopathy, a condition in patients with liver disease that is associated with an increased risk of…2016 American Transplant Congress
MELD as a Metric for Survival Benefit of Liver Transplantation.
MELD predicts waitlist mortality and thus, patients with higher MELD get higher priority in liver allocation. However, this disease severity based allocation system is controversial…2016 American Transplant Congress
Systematic Review and Meta-Analysis of the Impact of Computed Tomography Assessed Skeletal Muscle Mass on Outcome in Patients Awaiting or Undergoing Liver Transplantation.
BackgroundAlthough liver transplant outcome has improved significantly, the shortage of human organs remains prevalent. Therefore, strict patient selection is of paramount importance. Recently, low CT-assessed…2016 American Transplant Congress
Human Leukocyte Antigen (HLA) Mismatch Impact on Lung transplants outcomes.
PurposeReports on the impact of HLA mismatching on survival and its role in the development of bronchiolitis obliterans syndrome (BOS) or chronic allograft lung dysfunction…2016 American Transplant Congress
Clinical Significance of C3d Binding Donor Specific Anti-HLA Antibodies (DSA) Detected by Single Antigen Beads (SAB) After Kidney Transplantation.
A new Luminex-based SAB method detects DSA compliment fixing via C3d-binding. This study compares the clinical outcomes in kidney recipients that developed de novo DSA…2016 American Transplant Congress
Antibody-Mediated Rejection Can Be Assessed by Histology When DSA Is Unknown or Negative.
Diagnosis of antibody-mediated rejection (ABMR) in kidney transplants currently requires the presence of donor-specific antibody (DSA) and histologic lesions above somewhat arbitrary cutoffs. DSA is…2016 American Transplant Congress
Evaluation of Dose Dependent Rabbit Anti-Thymocyte Globulin Induction in Risk-Stratified Kidney Transplant Recipients.
UC San Diego Health System, San Diego, CA.
Background: Rabbit anti-thymocyte globulin (rATG) is a depleting polyclonal antibody often used for induction following kidney transplantation to help prevent acute rejection. The optimal dosage…2016 American Transplant Congress
Induction Therapy in Low Risk African American Kidney Transplant Recipients: Donor Factors.
African Americans (AA) are at a higher risk of acute rejection and graft loss compared to non-AA kidney transplant (KT) recipients. Guidelines specify induction choices…2016 American Transplant Congress
The Environmental Impact of Dialysis vs Transplantation.
Introduction: Hemodialysis has a large environmental impact because it uses large volumes of water, medical supplies and energy. A patient undergoing weekly dialysis treatment (three…
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