ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Serial Peripheral Blood Mononuclear Cell Expression Profiling Reveals Inflammatory Genomic Storm Following Mechanical Circulatory Support Surgery.

    G. Godoy,1 G. Bondar,1 A. Esmaeili,1 E. Arellano,1 E. Chang,1 M. Bakir,1 J. Chittoor,1 R. Togashi,1 N. Fazli,1 C. Starling,1 E. Oh,1 S. Toluie,1 Z. Yang,2 D. Tran,1 M. Cadeiras,1 N. Wisniewski,1 M. Kwon,1 J. Schaenman,1 Y. Korin,1 M. Rosetti,1 E. Reed,1 M. Deng.1

    1University of California, Los Angeles, Los Angeles, CA; 2Shanxi Medical University First Hospital, Taiyuan, Shanxi, China.

    Introduction: The main cause of death in patients with Advanced Heart Failure (AdHF) is the Multi-Organ Dysfunction (MOD) Syndrome. Immune system aberrancy after Mechanical Circulatory…
  • 2016 American Transplant Congress

    Development of a Vascularized Thymus-Sternum Composite Tissue Allograft Model in Non-Human Primates.

    N. O'Neill, S. Sendil, Y. Zhao, A. Hershfield, I. Tatarov, G. Braileanu, W. Hassanein, D. Parsell, A. Azimzadeh, L. Burdorf, R. Pierson, A. Nam.

    Surgery, University of Maryland, Baltimore, MD.

    Purpose: Vascularized composite allotransplantation (VCA) has demonstrated clinical success with standard immunosuppressive strategies in face, hand, and forearm transplantations. We developed a non-human primate model…
  • 2016 American Transplant Congress

    Utility of a Routine Bench Cholangiogram for Deceased Split Liver Procedure.

    N. Battula, R. Anbarasan, V. Thumma, K. Sharif, T. Perera, P. Muiesan, D. Mirza.

    Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; Liver Unit, Birmingham Children's Hospital, Birmingham, United Kingdom.

    Background: Biliary complications can result in a significant morbidity for split liver graft recipients. The segmental biliary anatomy, particularly the left biliary system is poorly…
  • 2016 American Transplant Congress

    A Multidisciplinary Approach to Reviewing Patient Care in Abdominal Transplantation.

    S. Lerner, M. Resta-Flarer, R. Shapiro, S. Florman, L. Kim-Schluger, V. Nair.

    Mount Sinai Hospital, New York, NY.

    Purpose: Unbiased review of patient care in solid organ transplantation is difficult but essential for improving patient safety. In October 2013 we created a process…
  • 2016 American Transplant Congress

    Banked EBV-Specific T-Cells for Treatment of Rituximab Refractory EBV+ B-Cell Lymphoma in Solid Organ Transplantation Recipients.

    S. Prockop,1 E. Doubrovina,1 C. Sauter,2 S. Suser,1 R. O'Reilly.1

    1MKSCC, New York, NY; 2MSKCC, New York, NY.

    Morbidity and mortality from EBV-induced post-transplant lymphoproliferative disease (EBV+ PTLD) can complicate solid organ transplant (SOT), particularly in those seronegative prior to transplant and in…
  • 2016 American Transplant Congress

    Combination of Delayed Kidney Transplant (KT) and Better Quality Kidneys Offers Excellent Patient Survival in Combined Liver-Kidney Transplantation (CLKT).

    B. Ekser, R. Mangus, J. Fridell, C. Kubal, D. Bayt, S. Nagaraju, P. Mihaylov, J. Powelson, W. Goggins, A. Tector.

    Transplant Division, Department of Surgery, Indiana University, Indianapolis, IN.

    Background: Despite prioritizing high MELD patients with the share-35 policy, patient survival in CLKT is relatively low. We previously showed the positive impact of delayed…
  • 2016 American Transplant Congress

    Intervention Development for the Allocation System Changes for Equity in kidNey Transplantation (ASCENT) Study.

    K. Smith,1 J. Gander,1 M. Basu,1 S. Pastan,1 S. Mohan,2 C. Escoffery,1 L. Plantinga,1 S. Kalloo,2 G. Green,3 A. Berlin,4 G. Renville,5 T. Browne,6 N. Turgeon,1 S. Caponi,7 J. Krisher,8 R. Patzer.1

    1Emory University, Atlanta, GA; 2Columbia University, New York, NY; 3American Association of Kidney Patients, Tampa, FL; 4Southeastern Kidney Transplant Coalition, Atlanta, GA; 5National Kidney Foundation, Atlanta, GA; 6University of South Carolina, Columbia, SC; 7ESRD Network 2, Lake Success, NY; 8ESRD Network 6, Raleigh, NC.

    Background: Recent changes in the kidney allocation system (KAS) are expected to reduce racial disparities in kidney transplantation (KTx). However, dialysis facilities may not be…
  • 2016 American Transplant Congress

    “Day 2 Discharge” After Kidney Transplantation: Complications, Health Care Utilization, and Long-Term Clinical Outcomes.

    A. Mathur, N. Katariya, A. Welu, J. Chang, R. Heilman, A. Singer, H. Khamash, H. Chakkera, W. Hewitt, D. Haakinson, M. Maningo-Salinas, E. Oakley, A. Moss, K. Reddy.

    Transplant Center, Mayo Clinic, Phoenix.

    Background: Reducing kidney transplant length of stay is a priority for many stakeholders. We aimed to determine whether very early discharge – on or before…
  • 2016 American Transplant Congress

    Influence of Lipid Levels on Cardiovascular Events After Early Conversion from Calcineurin Inhibitor to Everolimus: 24 M Analysis of the ELEVATE Study.

    M. van der Giet,1 J. de Fijter,1 F. Oppenheimer,1 L. Toselli,1 G. Russ,1 P. Lopez,2 J. Aguilar,2 P. Bernhardt,2 Z. Wang,3 J. Cruzado,1 H. Holdaas.1

    1ELEVATE study group, Berlin, Germany; 2Novartis pharma AG, Basel, Switzerland; 3Novartis Pharmaceutical Corporation, East Hanover, NJ.

    Background: Immunosuppressive therapies are probably the most important cause of hyperlipidemia post-renal transplantation (RTx). Lipid abnormalities represent important biomarkers for cardiovascular (CV) risk. Here, we…
  • 2016 American Transplant Congress

    A Prospective Carfilzomib-Based Desensitization Trial: Phase 1 Results.

    S. Tremblay,1 A. Shields,1 R. Alloway,1 P. Brailey,1 B. Abu Jawdeh,1 T. Latif,1 J. Driscoll,1 M. Pando,2 A. Girnita,1 E. Woodle.1

    1U Of Cincinnati, Cincinnati; 2Mayo Clinic, Phoenix.

    Carfilzomib (CFZ) is mechanistically distinct from bortezomib as it is an irreversible PI. Results from phase 1 of a CFZ desensitization (DS) trial are presentedMethods:…
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