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American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Comparison of Clinical Outcomes in Lung Transplant Patients with and without Preoperative Pulmonary Hypertension.

    A. Kalya, M. Boga, S. Dasyam, R. Walia, M. Smith, R. Bremner, A. Omar, V. Patel, E. Kuo, J. Huang, S. Hashimi.

    St. Joseph's Hospital and Medical Center, Phoenix.

    Purpose: End-stage lung disease patients (pts) who undergo lung transplantation (LTx) with an elevated mean pulmonary artery pressure (mPAP) are known to have adverse outcomes.…
  • 2016 American Transplant Congress

    Postoperative Rebound of Anti-Blood Type Antibodies and Antibody-Mediated Rejection After ABO-Incompatible Living Related Kidney Transplantation – Is Prophylactic Treatment Necessary?

    H. Ishida, T. Kondo, T. Shimizu, T. Nozaki, K. Tanabe.

    Urology, Tokyo Women's Medical University Hospital, Tokyo, Japan.

    PURPOSE: The role of postoperative anti-ABO titers in acute rejection under our current immunosuppressive regimen remains unclear. Some institutions recommend postoperative therapeutic plasma exchange to…
  • 2016 American Transplant Congress

    Tocilizumab as Treatment for Persistent Chronic Active Antibody Mediated Rejection.

    H. Fernandez, S. Patel, M. Chiles, L. Ratner, R. Crew.

    Columbia University Medical Center, NYC.

    Intro: CAAMR is an increasingly recognized cause of renal allograft failure with limited treatment options. Many patients with CAAMR have engagement of both T and…
  • 2016 American Transplant Congress

    IVIG and High Dose Steroid Treatment of Transplant Glomerulopathy Effectively Slows Progression of Loss of Renal Allograft Function.

    K. Sablik,1 C. Looman,2 M. Clahsen-van Groningen,3 J. Damman,3 D. Roelen,4 M. van Agteren,1 M. Betjes.1

    1Nephrology and Transplantation, Erasmus MC University Center, Rotterdam, Netherlands; 2Biostatistics, Erasmus MC University Center, Rotterdam, Netherlands; 3Pathology, Erasmus MC University Center, Rotterdam, Netherlands; 4Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, Netherlands.

    Introduction Transplant glomerulopathy (TG) is commonly associated with chronic antibody mediated rejection and is a major cause of late kidney allograft loss with no established…
  • 2016 American Transplant Congress

    Serum Levels of Soluble Myeloid Antigens After Kidney Allograft Transplantation.

    I. Striz, E. Cecrdlova, A. Sekerkova, J. Slatinska, V. Svachova, O. Viklicky.

    Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic.

    Mononuclear phagocytes and neutrophils play a key role in early responses against the transplanted kidney allograft. It is expected that during the reperfusion of kidney…
  • 2016 American Transplant Congress

    Early Changes to Kidney Distribution Under the New Kidney Allocation System.

    A. Massie,1 X. Luo,1 B. Lonze,1 N. Desai,1 A. Bingaman,2 M. Cooper,3 D. Segev.1

    1JHU, Baltimore; 2Methodist, San Antonio; 3Georgetown, Washington.

    In December 2014, the Kidney Allocation System (KAS), a major change to kidney allocation, was implemented, granting increased priority to younger candidates and candidates with…
  • 2016 American Transplant Congress

    Early Impact of the New Kidney Allocation System (KAS) in Highly Sensitized Patients.

    D. Mompoint-Williams, R. Gaston, G. Jeremy, J. Locke, V. Kumar.

    University of Alabama at Birmingham, Birmingham, AL.

    PurposeHighly sensitized (HS) patients, defined as a PRA of 99-100% are awarded additional priority points in the new KAS instituted December 2014. We evaluated the…
  • 2016 American Transplant Congress

    Persufflation Improves Viability and Function of Porcine Kidneys Relative to Static Cold Storage.

    C. Min,1 L. Steyn,2 A. Pandey,3 R. Harland,2 J.-P. Galons,4 K. Papas.2

    1Physiology, University of Arizona, Tucson, AZ; 2Surgery, University of Arizona, Tucson, AZ; 3Electrical and Chemical Engineering, University of Arizona, Tucson, AZ; 4Medical Imaging, University of Arizona, Tucson, AZ.

    The use of marginal organs demands optimization of organ storage and quality assessments prior to transplantation. Organs from donors after cardiac death (DCD) are exposed…
  • 2016 American Transplant Congress

    Prolonged Normothermic Ex Vivo Kidney Perfusion Is a Safe Preservation Technique for Kidney Transplantation: A New Opportunity for the Storage, Assessment and Repair of Kidney Grafts.

    J. Kaths,1,2,3 J. Echeverri,1 N. Goldaracena,1 K. Louis,1 Y.-M. Chun,1 I. Linares,1,3 A. Wiebe,1 P. Yip,5 R. John,5 I. Mucsi,6 A. Ghanekar,1 D. Bagli,7,3 D. Grant,1 L. Robinson,2,3 M. Selzner.1,3

    1Department of Surgery, Multi Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 2Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada; 3Institute of Medical Science, University of Toronto, Toronto, ON, Canada; 4Department of General, Visceral, and Transplant Surgery, University Medical Center Mainz, Mainz, Germany; 5Laboratory Medicine & Pathobiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 6Department of Medicine, Toronto General Hospital, University Health Network, Toronto, ON, Canada; 7Departments of Surgery (Urology) & Physiology, The Hospital for Sick Children, Toronto, ON, Canada.

    Hypothermic kidney storage causes preservation injury. We investigated whether SCS can be safely replaced with prolonged normothermic ex vivo kidney perfusion (NEVKP). Right kidneys were…
  • 2016 American Transplant Congress

    Clinical Outcomes of Kidney Allograft Recipients with Apolipoprotein L1 (APOL1) Risk Alleles from Living Kidney Donors.

    C. Dorr,1,2,3 A. Hart,1,2,3 D. Schladt,1 A. Muthusamy,1 R. Mannon,4 W. Oetting,2 A. Matas,2 P. Jacobson,2 A. Israni.1,2,3

    1Minneapolis Medical Research Foundation, Minneapolis; 2University of Minnesota, Minneapolis; 3Hennepin County Medical Center, Minneapolis; 4University of Alabama, Birmingham.

    Background:Apolipoprotein L1 (APOL1) alleles G1 and G2 in deceased donors are associated with poor kidney allograft survival. However, the effect of these alleles in living…
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