Am J Transplant, Volume 16, Suppl 3 Archives - Page 11 of 180 - ATC Abstracts

2016 American Transplant Congress
The Medication Level Variability Index (MLVI), a Behavioral Biomarker, Predicts Late Allograft Rejection in Pediatric Liver Transplant Recipients – A Prospective Multisite Study.
E. Shemesh,¹ J. Bucuvalas,² R. Anand,³ R. Venick,⁴ E. Alonso,⁵ J. Mitchell,³ R. Annunziato,¹ G. Mazariegos,⁶ B. Shneider.⁷
¹Mount Sinai, New York; ²Children's Hospital, Cincinnati; ³Emmes Corporation, Rockville; ⁴UCLA, Los Angeles; ⁵Lurie Children's Hospital, Chicago; ⁶Children's Hospital, Pittsburgh; ⁷Children's Hospital, Texas.
Objective: The MALT [Medication Adherence in children who had a Liver Transplant (LT), NCT-01154075, R01DK080740 (NIDDK)] multisite study prospectively evaluated a biomarker for erratic medication…
2016 American Transplant Congress
Big Data Predictive Solution to Optimize Kidney Transplant Outcome and Resource Utilization.
T. Srinivas, D. Northrup, P. Mauldin, D. Taber, Z. Su, J. Zhang, M. Daniels, W. Moran.
MUSC, Charleston.
Objective: Transplant (Tx) programs often use data in reaction to regulation vs. optimizing outcomes through data driven clinical care. Tx specific issues can detract from…
2016 American Transplant Congress
Development and Validation of a Molecular Microscope Diagnostic System (MMDx) for Heart Transplant Biopsies.
P. Halloran,¹ D. Kim,¹ A. Loupy,² J.-P. Duong Van-Huyen,² P. Bruneval,³ L. Potena,⁴ O. Leone,⁴ J. Reeve.¹
¹University of Alberta, Edmonton, Canada; ²Necker Hospital, Paris, France; ³Hopitaux de Paris, Paris, France; ⁴Bologna University, Bologna, Italy.
The diagnosis of heart transplant rejection by histology in endomyocardial biopsies (EMB) is challenging. A molecular system (MMDx) has been developed to assess both T…
2016 American Transplant Congress
Pancreas After Islet Transplantation – A Successful Treatment Option After a Failed Islet Transplant.
R. Gruessner, N. Ozden, V. Whittaker, V. Aggarwal, A. Gruessner.
Department of Surgery, SUNY Upstate Medical University, Syracuse, NY.
Introduction: Pancreas after islet (PAI) transplantation (tx) is a treatment option for patients seeking insulin independence through a whole organ transplant after a previous, failed…
2016 American Transplant Congress
Provider Attitudes Toward Shared Mobile Decision Aid Utilized Among Patients Evaluated for Kidney Transplantation: iChoose Kidney Randomized Trial.
M. Basu,¹ S. Pastan,¹ S. Mohan,² M. Wolf,³ J. Friedewald,³ D. Ladner,³ K. Smith,¹ L. McPherson,¹ A. Russell,³ M. Chiles,² R. Patzer.¹
¹Emory University, Atlanta, GA; ²Columbia University, New York, NY; ³Northwestern University, Evanston, IL.
Introduction: Although kidney transplantation (KTx) provides significant survival advantage over long-term dialysis, many end stage renal disease (ESRD) patients are not educated about KTx options.…
2016 American Transplant Congress
A Retrospective Study of Simultaneous Bilateral Nephrectomies and Renal Transplantation in Recipients with Polycystic Kidney Disease.
E. Grodstein, D. Kaufman.
Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI.
Background: Many strategies regarding timing of native nephrectomies exist for patients with symptomatic polycystic kidney disease (PCKD). We hypothesize that the timing of bilateral nephrectomies…
2016 American Transplant Congress
Impact of Induction Therapy on Cardiovascular Events in Kidney Transplant Recipients.
S. Sandal,^1,2 S. Bae,² A. Massie,² M. Cantarovich,¹ D. Segev.²
¹MUHC, Montreal, Canada; ²JHU, Baltimore.
Cardiovascular events (CVE) are one of leading causes of mortality in kidney transplant (KT) recipients and ATG use is reported as a risk factor. We…
2016 American Transplant Congress
Initial Experience with Donor Specific Tregs in Kidney Transplantation.
J. Markmann,¹ E. Guinan,² E. Geissler,³ G. Cole,² S. Germana,¹ J. Kim,¹ B. Sawitzki.⁴
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA; ²Hematology/Oncology, Dana-Farber Cancer Center, Boston, MA; ³Surgery, Universitätsklinikum Regensburg, Regensburg, Germany; ⁴Institute of Medical Immunology, Charite Universitätsmedizin, Berlin, Germany.
Systematic multicenter clinical evaluation of regulatory cells is being conducted by the EU supported ONE Study trial in which each site is administering a different…
2016 American Transplant Congress
A Users Guide to Maximizing Utility and Outcome in >70 Year Old Donors.
K. Halazun, E. Przybyszewski, B. Samstein, E. Verna, A. Fox, R. Brown, J. Emond.
Liver Transplant & HPB Surgery, Weill Cornell Medical College, NY, NY.
Background Among 10 million stroke fatalities in the US since 2002, donated livers were recovered from 28,313. Unfortunately, only 2,402 livers were yielded from 7.5…
2016 American Transplant Congress
αLFA-1 Monotherapy Induced Tolerance Is Dependent on Indirect CD8 T-Cells and Augments a Population of CD8 Cells with a Suppressor Phenotype.
R. Plenter,¹ M. Coulombe,² T. Grazia,¹ R. Gill,² M. Zamora,¹ B. Pietra.³
¹Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO; ²Department of Surgery, University of Colorado, Aurora, CO; ³Division of Pediatric Cardiology, University of Florida, Gainesville, FL.
We sought to investigate some of the requirements for tolerance induction to cardiac allografts utilizing αLFA-1 mAb monotherapy. Having previously demonstrated that CD8 T-cells are…