ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Fifty Is the New 40? An Argument to Uncap the MELD Score.

    J. DiNorcia,1 Y. Genyk,1 K. Andreoni,4 W. Kim,3 J. Levitsky,5 D. Mulligan,6 R. Sung,7 M. Nadim.1

    1Univ of Southern California, Los Angeles, CA; 2Stanford University, Palo Alto, CA; 3Univ of Florida, Gainesville, FL; 4Northwestern Univ, Chicago, IL; 5Yale Univ, New Haven, CT; 6Univ of Michigan, Ann Arbor, MI.

    Background: The MELD score is used to prioritize patients awaiting liver transplantation (LT) and has been capped at 40 to prevent transplant futility in patients…
  • 2016 American Transplant Congress

    Outcomes for Liver Transplantation Using Organs from Donation After Cardiac Death Donors: A Single Center Experience.

    J. Vanatta, X. Zhao, V. Puri, R. Helmick, S. Nair, S. Satapathy, J. Eason.

    Transplantation, University of Tennessee/Methodist University Transplant Institute, Memphis, TN.

    Purpose: The use of donation after cardiac death (DCD) donors provides opportunity to help meet the demand for allografts needed for liver transplantation. However, concern…
  • 2016 American Transplant Congress

    Transplanting the Extremely Sensitized Patient: The University of Wisconsin Experience with the New Kidney Allocation System.

    E. Grodstein, R. Bennett, J. Anderson, G. Press, A. Djamali, D. Kaufman, R. Redfield.

    Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI.

    Background: The new UNOS kidney allocation system (KAS) prioritizes the transplant of highly sensitized patients with a calculated Panel Reactive Antibody (cPRA) ≥80 and extremely…
  • 2016 American Transplant Congress

    6 Minute Walk Test and FVC Analysis: A New Method to Prioritize Organ Allocation for Patients with COPD.

    I. Timofte, M. Terrin, M. Wijesinha, P. Sanchez, R. Pierson, E. Barr, J. Kim, Z. Kon, S. Pham, A. Iacono.

    University of Maryland, Baltimore, MD.

    Purpose: Lung transplantation remains the final therapeutic option for patients with end stage lung disease. COPD being one of the most severe common lung diseases…
  • 2016 American Transplant Congress

    Inconsistent HLA Antibody Reactivity Detected with Different Solid-Phase Assays.

    A. Jaramillo,1 L. Nelson,1 Y. Desmarteau,1 B. Labuda,2 K. Barrios,2 J. Lunz,2 R. Heilman,3 M. Pando.1

    1Department of Laboratory Medicine and Pathology, Mayo Clinic, Phoenix, AZ; 2Gift of Hope Organ & Tissue Donor Network, Itasca, IL; 3Department of Medicine, Mayo Clinic, Phoenix, AZ.

    Precise determination of HLA antibodies is essential for patients awaiting transplantation. HLA antigens that are recognized by a patient are listed in UNOS as unacceptable…
  • 2016 American Transplant Congress

    Preformed Antibodies Against AT1R and EDNRA Correlate with Rejection Post-Transplant.

    A. Gareau,1 C. Wiebe,1,2 D. Pochinco,2 I. Gibson,3 D. Rush,1 P. Nickerson.1,2,4

    1Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; 2Diagnostic Services of Manitoba, Winnipeg, MB, Canada; 3Pathology, University of Manitoba, Winnipeg, MB, Canada; 4Immunology, University of Manitoba, Winnipeg, MB, Canada.

    Studies have investigated the potential pathogenic effects of non-HLA antibodies (Ab), with a few reporting that Ab against the angiotensin II type 1 receptor (AT1R)…
  • 2016 American Transplant Congress

    Pharmakokinetics of Prolonged-Release Formulation of Tacrolimus: Comparison of AUC0-24 and Concentration at 10 Time Points.

    K. Unagami,1 M. Okumi,2 M. Furusawa,2 T. Hirai,2 T. Shimizu,2 K. Omoto,2 M. Inui,2 H. Ishida,2 K. Nitta,1 K. Tanabe.2

    1Nephrology, Tokyo Women's Medical University, Tokyo, Japan; 2Urology, Tokyo Women's Medical University, Tokyo, Japan.

    Background:Use of an appropriate immunosuppressant is necessary for good graft survival in kidney transplantation (KTx). Currently, a prolonged-release formulation of tacrolimus (Graceptor or Adovagraf, Astellas…
  • 2016 American Transplant Congress

    A Prospective Randomized Study to Evaluate the Efficacy and Safety of Rabbit Antithymocyte Globulin (rATG) 3mg/Kg vs. 6mg/Kg in Kidney Transplant Patients Under Minimization Maintenance Immunosuppressive Regimen.

    T. Sandes-Freitas, J. Junqueira Junior, M. Oliveira, C. Girão, R. Esmeraldo.

    Hospital Geral de Fortaleza, Fortaleza, Brazil.

    Background: rATG dosed from 4.5 to 7.5mg/kg has been the standard of care in most transplant centers. Recent studies have demonstrated similar efficacy with doses…
  • 2016 American Transplant Congress

    Development of an Integrated Transplant Data Mart for Customized Data Reporting.

    R. Patzer, K. Little, J. Kirsch, J. Weaver, A. Adams.

    Emory University, Atlanta.

    Background: Transplant centers have a large amount of clinical data from multiple data sources that are utilized for quality tracking of clinical outcomes, regulatory reports,…
  • 2016 American Transplant Congress

    Immunosuppressive Actions of CLI95 and CORM401 on TLR4 in Renal Ischemia Reperfusion Injury.

    P. Luke,1,2,5 G. Cepinskas,1,4 H. Alharbi,3,5 A. Haig,3,5 R. Bhattacharjee.1,2,5

    1Matthew Mailing Centre, London Health Sciences Centre, London, Canada; 2Surgery, Western University, London, Canada; 3Pathology and Laboratory Medicine, Western University, London, Canada.

    Background: Kidneys from all donor sources are highly sensitive to ischemia-reperfusion injury (IRI). However, grafts donated after cardiac death (DCD) sustain an increased incidence of…
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