Am J Transplant, Volume 16, Suppl 3 Archives - Page 101 of 180 - ATC Abstracts

2016 American Transplant Congress
Comparison of De Novo Donor Specific Antibody Formation for Kidney Transplant Recipients Induced with Thymoglobulin or Basiliximab.
A. Gong, K. Lee, S. Patel, M. Brande, R. Dhawan, C. Parke, M. Smogorzewski, L. Aguirre, B. Duong, S. Alexopolus, Y. Qazi.
Division of Transplantation, University of Southern California, Los Angeles, CA.
Background: Thymoglobulin (ATG) and basiliximab (Bas) induction are commonly used therapies to prevent allograft rejection in kidney transplant recipients (KTx). Formation of donor specific antibodies…
2016 American Transplant Congress
National Trends in Liver Discards: The Weekend Effect.
D. Carpenter,¹ S. Mohan,² K. Halazun,³ E. Verna,⁵ M. Chiles,² G. Charak,¹ L. Ratner.⁴
¹Surgery, Columbia University Medical Center, New York City, NY; ²Medicine, Division of Nephrology, Columbia University Medical Center, New York City, NY; ³Department of Surgery, Division of Transplantation, Weill Cornell Medical Center, New York City, NY; ⁴Department of Surgery, Division of Transplantation, Columbia University Medical Center, New York City, NY; ⁵Department of Medicine, Center for Liver Disease and Transplantation, Division of Digestive and Liver Diseases, Columbia University Medical Center, New York City, NY.
Overall organ discard rates have increased over the last decade. Given the current organ shortage, understanding factors that contribute to the discard of livers is…
2016 American Transplant Congress
Reduced Incidence of Cytomegalovirus Infection in Kidney Transplant Recipients Receiving Everolimus: A Cost-Effectiveness Analyses.
H. Tedesco-Silva, C. Felipe, A. Brigido, M. Cristelli, M. Paula, A. Bessa, P. Ruppel, J. Medina-Pestana.
Nephrology Division, Hospital do Rim - UNIFESP, Sao Paulo, Brazil.
A cost-effectiveness analysis was performed using data from a prospective single center trial where de novo kidney transplant recipients received a single 3 mg/kg dose…
2016 American Transplant Congress
Recombinant TSGL-Ig Protects Liver Endothelial Cells Against Prolonged Cold Preservation Injury in Mouse Liver Transplantation.
C. Zhang,^1,2 H. Ji,¹ Y. Liu,^1,2 Y. Zhang,^1,2 X.-D. Shen,¹ F. Gao,¹ R. Busuttil, G. Shaw, J. Kupiec-Weglinski.
¹Dumont-UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles, CA; ²Department of Surgery, Division of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
Background: Liver endothelial cells (LEC) suffer from ROS-mediated stress in the pathogenesis of liver ischemia-reperfusion injury (IRI). We used a novel recombinant form of soluble…
2016 American Transplant Congress
Distinctive Roles of Gsk3 Inhibitory Phosphorylation in Liver Inflammatory Immune Response and Hepatocellular Injury Against Ischemia Reperfusion.
H. Zhou,^1,2 J. Zhu,¹ S. Yue,¹ R. Busuttil,¹ J. Kupiec-weglinski,¹ L. Lu,² Y. Zhai.¹
¹Surgery, David Geffen School of Medicine-UCLA, Los Angeles, CA; ²Liver Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Background & AimsGlycogen synthase kinase 3 (Gsk3) a and b are ubiquitously expressed, constitutively active serine/threonine kinases, which play complex roles in cell activation, proliferation…
2016 American Transplant Congress
Attenuation of Warm Hepatic Ischemia-Reperfusion Injury by Bruton's Tyrosine Kinase Inhibition.
A. Zarrinpar,¹ T. Palumbo,¹ K. Nakamura,¹ C. Lassman,² R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
Bruton's tyrosine kinase (Btk) is a central player in multiple signaling pathways in lymphoid and myeloid cells, including neutrophils. Neutrophils are crucial effectors in the…
2016 American Transplant Congress
Measured Glomerular Filtration Rate of the Remaining Kidney Divided by Its Volume Prior to Donation Is a Predictor of the Long-Term Gain of Function in Living Kidney Donors.
M. Courbebaisse,¹ F. Gaillard,² A. Le Nestour,⁴ J.-M. Correas,³ H. Slimani-Thevenet,⁵ C. Leon,² D. Eladari,¹ M.-O. Timsit,⁶ P. Otal,⁷ G. Friedlander,¹ P. Houillier,¹ N. Kamar,⁸ C. Legendre.²
¹AP-HP, Georges Pompidou European Hospital, Physiology department, Paris Descartes University, and INSERM, Unit 1151, Paris, France; ²AP-HP, Hôpital Necker-Enfants Malades, Renal Transplantation Department, Paris Descartes University, Paris, France; ³AP-HP, Hôpital Necker-Enfants Malades, Radiology Department, and Paris Descartes University, Paris, France; ⁴University of Otago, Biostastistic department, Otago, New Zealand; ⁵AP-HP, Georges Pompidou European Hospital , Nuclear Medicine department, Paris Descartes University, and INSERM, Unit 1151, Paris, France; ⁶AP-HP, Georges Pompidou European Hospital , Nuclear Medicine department, Paris Descartes University, and INSERM, Unit 1151, Paris, France; ⁷Toulouse University Hospital, CHU Rangueil, Department of Radiology, Paul Sabatier University, Toulouse, France; ⁸Toulouse University Hospital, CHU Rangueil, Department of Nephrology and Organ Transplantation, Paul Sabatier University, INSERM U1043, IFR–BMT, CHU Purpan, Toulouse, France.
Predictors of long-term renal function in living kidney donors are a matter of debate. To describe the predictors of remaining kidney functional gain, we conducted…
2016 American Transplant Congress
End Stage Renal Disease (ESRD) Patients' Willingness to Accept Risks to Living Kidney Donors.
J. Gannon,¹ C. Thiessen,¹ K. Yu,¹ L. Skrip,¹ P. Reese,² E. Gordon,³ S. Kulkarni.¹
¹Yale University, New Haven; ²University of Pennsylvania, Philadelphia; ³Northwestern University, Chicago.
Background: While many potential living kidney donors (LKDs) are willing to accept high levels of ESRD risk, receipt of a living donor kidney is also…
2016 American Transplant Congress
The Impact of Total Ischaemic Time, Donor Age and the Pathway of Donor Death on Graft Outcomes After Deceased Donor Kidney Transplantation.
G. Wong,¹ A. Teixeira-Pinto,¹ C. Jeremy,¹ C. Jonathan,¹ M. Stephen,² L. Wai.³
¹University of Sydney, Sydney, Australia; ²University of Adelaide, Adelaide, Australia; ³University of Western Sydney, Perth, Australia.
Prolonged ischaemia is a known risk factor for delayed graft function and its interaction with donor characteristics, the pathways of donor death and graft outcomes…
2016 American Transplant Congress
Donor Interstitial Fibrosis and Tubular Atrophy (IFTA) Are Not Independent Risk Factors for a Lower GFR at One Year.
R. Heilman, I. Qaqish, M. Smith, H. Khamash, B. Kaplan, K. Reddy.
Mayo Clinic, Phoenix.
BackgroundDonor age is a determinant of allograft outcome after deceased donor kidney transplant (DDTx). Our aim was to determine if chronic changes on a reperfusion…