Am J Transplant, Volume 16, Suppl 3 Archives - Page 101 of 180 - ATC Abstracts

2016 American Transplant Congress
Which Is the Predictable Value of Post-Transplant HCC Recurrence Between Tumor-Related Factors at the Initial Diagnosis and the Transplantation?
J. Lee,^1,2 J. Lee,¹ J. Lee,³ S. Song,¹ J. Lee,¹ S.-K. Kwon,¹ M. Ju,^1,2 M. Kim,^1,2 G. Choi,^1,2 J. Choi,^1,2 S. Kim,^1,2 D. Joo.^1,2
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; ²Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Bundang, Korea.
Background: Milan criteria is best options to decide whether patients with HCC underwent liver transplantation. However, Milan Criteria is not including values at time of…
2016 American Transplant Congress
Living Donor Liver Transplantation for Sick Patients with MELD Score ≥ 35.
R.-S. Soong,¹ Y.-C. Wang,¹ C.-H. Cheng,¹ T.-H. Wu,¹ C.-F. Lee,¹ T.-J. Wu,¹ H.-S. Chou,¹ K.-M. Chan,¹ C.-S. Lee,² W.-C. Lee.¹
¹Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Taoyuan, Taiwan; ²Hepatology, Chang-Gung Memorial Hospital, Taoyuan, Taiwan.
Background: The liver transplant candidates with MELD score ≥ 35 were very sick and with high mortality without liver transplantation. All these patients are in…
2016 American Transplant Congress
Torque Teno Virus – Inverse Association with Late Silent Antibody Mediated Kidney Allograft Rejection.
G. Bond,¹ M. Schiemann,¹ F. Eskandary,¹ H. Herkner,² E. Puchhammer,³ R. Oberbauer,¹ G. Böhmig.¹
¹Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ²Emergency Medicine, Medical University of Vienna, Vienna, Austria; ³Virology, Medical University of Vienna, Vienna, Austria.
Clinical Problem and hypothesis: Antibody mediated rejection (ABMR) is a cardinal cause of late graft failure after kidney transplantation (KTX). A promising predictive diagnostic tool…
2016 American Transplant Congress
Do Highly Sensitized Recipients Benefit from the Immunological Advantages of Zero Mismatched (0MM) Deceased Donors (DD) Kidney Allografts?
N. Elfadawy,¹ S. Flechner,² J. Schold.²
¹Internal Medicine, Case Western Reserve University, Cleveland, OH; ²Glickman urological and kidney institute, Cleveland Clinic, Cleveland, OH.
HLA 0MM DD transplants have superior outcomes compared with outcomes for grafts with ≥1 HLA mismatches, but when past reports analyzed 0MM outcomes in DD,…
2016 American Transplant Congress
Gut Dysbiosis and Metabolic Disorders in Kidney Transplant Recipients.
M. Lecronier,¹ P. Tashk,¹ J. Aron-Wisnewsky,^2,3,4 E. Denamur,¹ O. Tenaillon,¹ B. Barrou,^4,5 J. Tourret.^1,4,5
¹IAME, UMR 1137, INSERM, Paris, France; ²Institute of Cardiometabolism and Nutrition, ICAN, Service de Nutrition, GH Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France; ³UMR_S U1166, équipe NutriOmics, INSERM, Paris, France; ⁴Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; ⁵AP-HP, Département d'Urologie, Néphrologie et Transplantation, GH Pitié-Salpêtrière Charles Foix, Paris, France.
IntroductionGut microbiota modifications (dysbiosis) have been observed in obese and/or diabetic patients. Kidney transplant recipients (KTR) are particularly exposed to the development of metabolic disorders,…
2016 American Transplant Congress
Serum Inflammatory Biomarkers in Kidney Transplant Recipients and Renal Donors.
J. Ramirez,¹ E. Cuevas,¹ J. Furuzawa,² L. Morales-Buenrostro,³ M. Lopez-Cervantes,² J. Alberu.¹
¹Transplantation, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ²Immunology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ³Nephrology, Inst Nal Ciencia Medicas y Nutricion SZ, Mexico City, Mexico; ⁴Medicine School, UNAM, Mexico City, Mexico.
Kidney transplant recipients (KTR) have an increased risk for cardiovascular events, graft failure, and death. It is unknown whether serum inflammatory biomarkers correlate with eGFR…
2016 American Transplant Congress
Delayed Graft Function Is an Independent Risk Factor for Renal Allograft Rejection.
T. Dienemann, S. Weber, J. Jacobi, K.-U. Eckardt, A. Weidemann.
Nephrology and Hypertension, Universitaetsklinikum Erlangen, Universiaet Erlangen Nuernberg, Erlangen, Germany.
Background: Numerous risk factors for delayed graft function (DGF) after kidney transplantation (KTx) have been identified. However the effect of DGF as an independent risk…
2016 American Transplant Congress
High Concentrations of CXCL9 and CXCL10 Chemokines but Not CXCL8 (IL-8), IL-6, TNF-a or IFN-g in Biopsy Tissue Are Associated with Pathological Staging of Rejection After Kidney Transplantation.
C. Falk,¹ C. Neudörfl,¹ K. Daemen,¹ J. Keil,¹ F. Lehner,² H. Haller,³ J. Schmitz,⁴ C. Blume,⁵ J.-H. Bräsen.⁴
¹Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; ²Department of Abdominal and Transplantation Surgery, Hannover Medical School, Hannover, Deutschland, Germany; ³Department of Nephrology and Hypertension, Hannover Medical School, Hannover, Deutschland, Germany; ⁴Institute of Pathology, Hannover Medical School, Hannover, Deutschland, Germany; ⁵Institute of Technical Chemistry, Leibniz University Hannover, Hannover, Deutschland, Germany.
Background: Extensive expression profiling efforts of biopsy tissue after kidney transplantation indicate that rejection, especially antibody-mediated rejection (AMR) can be defined by distinct signatures. Thus,…
2016 American Transplant Congress
ESAT-6 Inhibits Donor-Specific Memory CD8+ T Cell Generation and Alloimmune Responses.
Z. Dai,¹ H. Dai.²
¹Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China; ²University of Pittsburgh, Pittsburgh.
Inducing long-term transplant survival or tolerance without continuous global immunosuppression is a highly desired goal in organ transplantation because conventional immunosuppressive drugs usually cause severe…
2016 American Transplant Congress
Treg-Rich Organized Lymphoid Structures (TOLS) in Spontaneously Accepted Mouse Kidney Allografts.
C. Yang,¹ E. Farkash,² D. Ndishabandi,¹ R. White,¹ B. Jiang,¹ I. Aljabban,¹ P. Russell,¹ J. Madsen,¹ R. Colvin,¹ A. Alessandrini.¹
¹Center for Transplantation Sciences, Dept. of Surgery, Dept. of Pathology, Massachusetts General Hospital, Boston, MA; ²University of Michigan School of Medicine, Ann Arbor, MI.
Background: In many MHC mismatched strain combinations (e.g., DBA/2 to B6) kidney allografts are spontaneously accepted without immunosuppression. This tolerance is regulatory, initially dependent Foxp3+…