ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Weight Loss, But Not Weight Gain Is a Risk Factor for Graft Loss After Kidney Transplantation

E. Hendren, J. Dong, C. Kennedy, T. Myint, C. Rose, O. Johnston, J. Gill, J. Gill.

Division of Nephrology, University of British Columbia, Vancouver, Canada.

Meeting: 2015 American Transplant Congress

Abstract number: A182

Keywords: Graft failure, Weight

Session Information

Session Name: Poster Session A: Kidney: Cardiovascular and Metabolic

Session Type: Poster Session

Date: Saturday, May 2, 2015

Session Time: 5:30pm-7:30pm

 Presentation Time: 5:30pm-7:30pm

Location: Exhibit Hall E

Weight gain is common after kidney transplantation. In this analysis of n=92,688 adult 1st kidney transplant recipients with graft survival of ≥ 1 year between 2000-12, we determined the percent weight change during the 1st post transplant year and the association of percent weight change with graft survival. The percent weight change (figure) during the 1st post transplant year in patients sub-grouped by BMI at transplantation: Weight gain was common and inversely related to BMI at transplantation: 75%, 55%, 44%, 38%, 34%, 28% of patients with BMI <18.5, 18.5-24.9, 25.0-29.9, 30.0-34.9, 35.0-39.9, ≥ 40 kg/m2 had a percent weight gain >5% during the 1st year.

The table shows the results of separate Cox multivariate models stratified by BMI at transplantation. Patients with weight loss > 5% were at increased of graft loss and this was consistent in all BMI groups with the exception of underweight patients. In contrast, weight gain between 5.1-10.0% was associated with lower risk of graft loss. Even weight gain >10% was associated with either a decreased or unchanged risk of graft loss (table).

Table. Association of percent weight change in the first post transplant year with graft loss
BMI at Transplant N Stable Weight (percent change ± 5%) Weight loss >5.1% Weight Gain 5.1-10.0% Weight Gain >10.1%
All 92,688 1.00 1.21(1.16,1.27) 0.92(0.87,0.96) 0.98(0.92,1.01)
<18.5 2,491 1.00 0.81(0.47,1.40) 0.67(0.46,0.96) 0.63(0.48,0.83)
18.5-24.9 30,013 1.00 1.31(1.16,1.46) 0.88(0.79,0.98) 0.90(0.82,0.98)
25.0-29.9 31,351 1.00 1.15(1.05,1.25) 0.94(0.85,1.03) 0.99(0.91,1.08)
30.0-34.9 19,232 1.00 1.26(1.13,1.38) 1.00(0.89,1.12) 1.01(0.90,1.13)
35.0-39.9 7,547 1.00 1.05(0.91,1.22) 0.84(0.70,1.00) 0.97(0.81,1.00)
≥40.0 2,054 1.00 1.57(1.19,2.06) 0.98(0.69,1.38) 1.28(0.88,1.88)

These associations were consistent in secondary models that included adjustment for differences in rejection, DGF, and eGFR at 1 year after transplantation (data not shown).

We conclude that weight loss > 5 % but not weight gain after transplantation is a risk factor for graft loss. Other metrics of the change in body habitus after transplantation should be studied for their association with allograft survival.

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
  • Click to print (Opens in new window) Print

To cite this abstract in AMA style:

Hendren E, Dong J, Kennedy C, Myint T, Rose C, Johnston O, Gill J, Gill J. Weight Loss, But Not Weight Gain Is a Risk Factor for Graft Loss After Kidney Transplantation [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/weight-loss-but-not-weight-gain-is-a-risk-factor-for-graft-loss-after-kidney-transplantation/. Accessed May 31, 2025.

« Back to 2015 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences