Utility of a 10-Minute Functional Test as a Predictor of Kidney Transplant (KTP) Listing.
1Transplant Nephrology, University of Iowa, Iowa City, IA
2Transplant Nephrology, Iowa City Veterans Affairs Medical Center, Iowa City, IA
Meeting: 2017 American Transplant Congress
Abstract number: C150
Keywords: Age factors, Elderly patients, Kidney transplantation, Morbidity
Session Information
Session Name: Poster Session C: Kidney Complications III
Session Type: Poster Session
Date: Monday, May 1, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Purpose: Frailty is a measure of physiologic reserve that has been associated with poor outcomes after kidney transplant, but its use as a predictor for KTP listing has not yet been investigated.
Methods: We performed a single-center retrospective analysis of all patients being evaluated for KTP between October 2015 and October 2016. Patients were assessed utilizing four commonly used frailty tests: grip strength, the 30-second chair stand test, the chair sit and reach test, and the 8-feet up and go test. Age, gender, body mass index (BMI), reason for kidney disease, dialysis vintage, and comorbidities including diabetes mellitus (DM), stroke, and peripheral vascular disease were recorded. Patients unable to perform the frailty tests were excluded.
Results: 180 patients were studied. Using a t-test, there were no statistically significant correlations between frailty test results and KTP listing status.
| Variable (mean+SD) | Active(n=73) | Deferred(n=76) | Denied(n=31) | Overall(n=180) |
| Right Grip Strength | 30.0+9.0 (p=0.53) | 34.1+9.1 (0.47) | 31.9+8.6 (0.64) | 32.1+9.1 |
| Left Grip Strength | 39.9+9.9 (0.41) | 31.2+10.2 (0.31) | 28.9+8.2 (0.86) | 30.3+9.7 |
| 30-Second Chair Stand Test (Repetitions) | 9.9+5.9 (0.28) | 10.2+5.2 (0.74) | 8.2+5.9 (0.64) | 9.7+5.6 |
| Chair Sit and Reach Test (cm) | 4.6+7.4 (0.71) | 4.7+7.8 (0.50) | 5.1+9.2 (0.11) | 4.7+7.9 |
| 8-Foot Up and Go (seconds) | 6.1+3.1 (0.13) | 5.6+1.9 (0.99) | 7.6+3.3 (0.08) | 6.1+2.7 |
| Age | 61.9+8.8 (0.68) | 57.2+9.8 (0.30) | 63.5+7.1 (0.96) | 60.1+9.3 |
| BMI | 29.5+4.5 (0.59) | 29.3+4.2 (0.81) | 32.1+5.2 (0.59) | 29.9+4.6 |
| Time on Dialysis | 1.8+2.3 (0.43) | 1.5+2.0 (0.89) | 2.2+2.8 (0.06) | 29.9+2.26 |
| History of DM | 52% (n=38) | 64% (n=49) | 68% (n=21) | 60% (n=108) |
However, time to dialysis and 8-foot up and go test in patients who were denied were 0.06 and 0.08 respectively, approaching statistical significance.
Conclusions: This study failed to show statistically significant correlations between frailty test scores and KTP status. Limitations of this study include small sample size and single-center experience. Further research with a larger sample is needed in order to better characterize any potential associations.
CITATION INFORMATION: Swee M, Hornickel J, Kalil R. Utility of a 10-Minute Functional Test as a Predictor of Kidney Transplant (KTP) Listing. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Swee M, Hornickel J, Kalil R. Utility of a 10-Minute Functional Test as a Predictor of Kidney Transplant (KTP) Listing. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/utility-of-a-10-minute-functional-test-as-a-predictor-of-kidney-transplant-ktp-listing/. Accessed May 18, 2025.« Back to 2017 American Transplant Congress