*Purpose: The field of uterus transplantation, since the first birth to a uterus transplanted woman in 2014, continues to grow rapidly. As of today at least 13 babies have been born worldwide as a result. We aim to share our experience in performing uterus transplantation in a recipient with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome.

*Methods: Over a 2-year period we have performed 14 uterus transplantations in our institution using grafts from both deceased (n=2) and living donors (n=12). We used live action footage from surgery together with comprehensive illustrations, to demonstrate stepwise our technique of the recipient surgery in uterus transplantation. The main outcome measurements were surgery time, recipient complications, hospital stay, and success rate.

*Results: This video article summarizes the important steps in recipient evaluation, IVF, transplant surgery and follow-up important to optimize the outcome. We also analyze our inclusion criteria for suitable recipients. The video shows footage from an actual uterus transplantation outlining the vital steps which include bilateral end-to-side vascular anastomoses between the donor uterine arteries and uterine veins and/or utero-gonadal veins and the recipient’s external iliac vessels, and connection of the donor uterine graft and the recipient vagina.

*Conclusions: Uterine transplantation is the first available treatment of uterine factor infertility that affects 1-5% of women. Even though this is still experimental, the field is showing promising results with babies born from transplantation with grafts from both living and deceased donors.

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