ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

The Impact of Body Mass Index > 35 on Kidney Transplant Outcomes: A Systematic Review.

D. Walczak, E. Benedetti.

Organ Transplant, University of Illinois Hospital and Health Sciences System, Chicago, IL.

Meeting: 2016 American Transplant Congress

Abstract number: 389

Keywords: Kidney transplantation, Obesity, Outcome, Quality of life

Session Information

Date: Tuesday, June 14, 2016

Session Name: Concurrent Session: Disparities in Transplant Access and Outcomes

Session Time: 2:30pm-4:00pm

 Presentation Time: 3:30pm-3:42pm

Location: Room 312

Related Abstracts
  • Systematic Review and Meta-Analysis of the Impact of Computed Tomography Assessed Skeletal Muscle Mass on Outcome in Patients Awaiting or Undergoing Liver Transplantation.
  • Should Obese Patients Undergo Renal Transplantation? A Retrospective Analysis to Assess Whether Body Mass Index Can Affect Transplant Outcome.

Background: The increased prevalence of obesity (BMI > 30) among adults in the United States over the last two decades is reflected in the number of moderately (BMI 35-39) and morbidly (BMI > 40) obese patients awaiting kidney transplant (KTx). It is often debated whether the possible benefits are sufficient enough to advocate transplant over dialysis in this population. This systematic review examines the outcomes of moderately and morbidly obese KTx recipients.

Methods: Medline, PubMed, Ovid, Google scholar and CINAHL were systematically searched using the key words "obesity" "kidney transplant" "adults" and "bariatric surgery". Studies were included if they provided quantitative data pertinent to medical or surgical outcomes of KTx recipients with BMI > 35. Outcome measures included: graft survival, patient survival and glomerular filtration rate (GFR) at 1, 3 and 5 years, delayed graft function, biopsy proven rejection, lymphocele, wound infection and hematoma. An English language restriction was applied. Case reports, letters, editorials and reports in abstract form or conference proceedings were excluded. A total of 266 papers were screened for relevance, 18 met inclusion criteria and were incorporated in the review.

Results: Findings support an increased rate of wound complications and the need for rigorous assessment of comorbid cardiovascular conditions prior to transplant, but were inconclusive regarding the benefit of pre-transplant weight loss. Some report lower rates of patient and graft survival when compared to those with BMI <35. Importantly, there is evidence that KTx provides a significant survival benefit when compared to patients with BMI > 35 that were maintained on dialysis, and supports KTx in some morbidly obese patients with BMI ≥ 40. Health Related Quality of Life (HRQOL) was assessed in 1 study and was not significantly affected by BMI (range: 35-39).

Conclusion: Findings did not support arbitrary restrictions on KTx for moderately and morbidly obese patients and identified significant gaps in the current literature that must be addressed in future studies. Assessments of HRQOL in KTx recipients with BMI > 35 may help to clarify uncertainty regarding KTx by providing supportive evidence for clinical decision-making, resource allocation and healthcare policy in this population.

CITATION INFORMATION: Walczak D, Benedetti E. The Impact of Body Mass Index > 35 on Kidney Transplant Outcomes: A Systematic Review. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Walczak D, Benedetti E. The Impact of Body Mass Index > 35 on Kidney Transplant Outcomes: A Systematic Review. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/the-impact-of-body-mass-index-35-on-kidney-transplant-outcomes-a-systematic-review/. Accessed February 24, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Home
  • Search
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.