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The Effect of BMI on Renal Transplant Outcomes.

E. Giorgakis,1 K. Reddy,1 A. Singer,1 H. Khamash,2 R. Heilman.2

1Department of Surgery, Mayo Clinic, Phoenix, AZ
2Department of Medicine, Mayo Clinic, Phoenix, AZ

Meeting: 2017 American Transplant Congress

Abstract number: D259

Keywords: Graft failure, Kidney transplantation, Obesity

Session Information

Session Name: Poster Session D: Long Term Kidney Outcomes

Session Type: Poster Session

Date: Tuesday, May 2, 2017

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Hall D1

Purpose of the study was to explore the effect of BMI class on renal transplant outcomes.

Method: Single center retrospective analysis of deceased and living donor renal transplants performed through period 07/2003-07/2016. The cohort was divided into 4 BMI categories: non-obese, Class I, II and III obese (morbidly obese). Outcomes were graft survival, DGF, rejection, 1-year eGFR and length of stay (LOS).

Results: N=2424 patients. Median recipient BMI was 28 kg/m2. 40.1% of the recipients were obese (BMI≥30 kg/m2) and 3.8 % Class III obese (BMI≥40 kg/m2).

BMI ( kg/m2) <30 30-34.9 35-39.9 ≥40 p
non-obese Class I obese Class II obese Class III obese
n (%) 1453 (59.9) 593 (24.5) 285 (11.8) 93 (3.8) <.001
Living donor (%) 44.7 41.8 38.2 50.54 .087
KDPI (mean±SD) 0.54±0.275 0.51±0.274 0.52±0.235 0.42±0.21 .002
DGF (%) 23.3 28.7 37.9 30.1 .000
1 year rejection (%) 15.3 15.0 16.8 19.4 .659
1-year GFR 60.06±21.242 58.55±18.768 54.72±16.619 58.29±22.189 .006

Higher BMI recipients received lower KDPI kidneys (p=0.002). Obese recipients had higher DGF rates and lower1-year eGFR (p=0.006). LOS and rejection rates were similar. Also, graft survival was similar across all BMI groups, as well as among obese vs. non-obese and between BMI≥ 40 (Class III or morbidly obese) vs. BMI<40mg/m2 patients.Conclusion: With appropriate donor and recipient selection, obese and morbidly obese patients have acceptable outcomes after kidney transplantation and should not be excluded for transplant based on BMI criteria alone.

CITATION INFORMATION: Giorgakis E, Reddy K, Singer A, Khamash H, Heilman R. The Effect of BMI on Renal Transplant Outcomes. Am J Transplant. 2017;17 (suppl 3).

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To cite this abstract in AMA style:

Giorgakis E, Reddy K, Singer A, Khamash H, Heilman R. The Effect of BMI on Renal Transplant Outcomes. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/the-effect-of-bmi-on-renal-transplant-outcomes/. Accessed May 29, 2025.

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