The Effect of BMI on Renal Transplant Outcomes.
1Department of Surgery, Mayo Clinic, Phoenix, AZ
2Department of Medicine, Mayo Clinic, Phoenix, AZ
Meeting: 2017 American Transplant Congress
Abstract number: D259
Keywords: Graft failure, Kidney transplantation, Obesity
Session Information
Session Name: Poster Session D: Long Term Kidney Outcomes
Session Type: Poster Session
Date: Tuesday, May 2, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Purpose of the study was to explore the effect of BMI class on renal transplant outcomes.
Method: Single center retrospective analysis of deceased and living donor renal transplants performed through period 07/2003-07/2016. The cohort was divided into 4 BMI categories: non-obese, Class I, II and III obese (morbidly obese). Outcomes were graft survival, DGF, rejection, 1-year eGFR and length of stay (LOS).
Results: N=2424 patients. Median recipient BMI was 28 kg/m2. 40.1% of the recipients were obese (BMI≥30 kg/m2) and 3.8 % Class III obese (BMI≥40 kg/m2).
| BMI ( kg/m2) | <30 | 30-34.9 | 35-39.9 | ≥40 | p |
| non-obese | Class I obese | Class II obese | Class III obese | ||
| n (%) | 1453 (59.9) | 593 (24.5) | 285 (11.8) | 93 (3.8) | <.001 |
| Living donor (%) | 44.7 | 41.8 | 38.2 | 50.54 | .087 |
| KDPI (mean±SD) | 0.54±0.275 | 0.51±0.274 | 0.52±0.235 | 0.42±0.21 | .002 |
| DGF (%) | 23.3 | 28.7 | 37.9 | 30.1 | .000 |
| 1 year rejection (%) | 15.3 | 15.0 | 16.8 | 19.4 | .659 |
| 1-year GFR | 60.06±21.242 | 58.55±18.768 | 54.72±16.619 | 58.29±22.189 | .006 |
Higher BMI recipients received lower KDPI kidneys (p=0.002). Obese recipients had higher DGF rates and lower1-year eGFR (p=0.006). LOS and rejection rates were similar. Also, graft survival was similar across all BMI groups, as well as among obese vs. non-obese and between BMI≥ 40 (Class III or morbidly obese) vs. BMI<40mg/m2 patients.
Conclusion: With appropriate donor and recipient selection, obese and morbidly obese patients have acceptable outcomes after kidney transplantation and should not be excluded for transplant based on BMI criteria alone.
CITATION INFORMATION: Giorgakis E, Reddy K, Singer A, Khamash H, Heilman R. The Effect of BMI on Renal Transplant Outcomes. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Giorgakis E, Reddy K, Singer A, Khamash H, Heilman R. The Effect of BMI on Renal Transplant Outcomes. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/the-effect-of-bmi-on-renal-transplant-outcomes/. Accessed November 22, 2024.« Back to 2017 American Transplant Congress