ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Role of Cardiac Rehabilitation after Heart Transplantation in the Reduction of Cardiac Allograft Vasculopathy, The

M. Kittleson, J. Patel, M. Rafiei, A. Osborne, D. Chang, L. Czer, J. Kobashigawa

Cedars-Sinai Heart Institute, Los Angeles, CA

Meeting: 2013 American Transplant Congress

Abstract number: C1429

Related Abstracts
  • Is There a Protective Value for Low Level Donor Specific Antibodies to Prevent Cardiac Allograft Vasculopathy After Heart Transplant?
  • Severity of Cardiac Allograft Vasculopathy after Heart Transplant Is Reduced with Proliferation Signal Inhibitors

BACKGROUND: Cardiac rehabilitation after heart transplantation has been documented to be beneficial for increased physical activity via a randomized trial using cardiopulmonary stress testing. It is not clear as to whether cardiac rehabilitation in the first year after transplant leads to better long-term outcome.

METHOD: We surveyed 164 heart transplant patients transplanted between 1991 and 2011, who underwent formal cardiac rehabilitation in the first year post-transplantation and compared them to 233 patients who did not undergo cardiac rehabilitation. End points include 5-year freedom from cardiac allograft vasculopathy (CAV). and non-fatal major adverse cardiac events (NF-MACE, defined as myocardial infarction, heart failure, need for percutaneous cardiac intervention, stroke).

RESULTS: Patients who underwent cardiac rehabilitation compared to those that did not had significantly greater 5-year freedom from CAV (85% vs 76%, p=0.024). There was no difference in baseline risk factors (except the rehab group being older) and 1-year freedom from treated rejection between groups.

Outcomes No Cardiac Rehab (N=233) Cardiac Rehab (N=164) p-value
5-Year Freedom from CAV 76% 85% 0.024
5-Year Freedom from NF-MACE 87% 89% 0.526
1-Year Freedom from Any-Treated Rejection 87% 85% 0.644
BMI at Baseline, Mean ± SD 25.0 ± 4.3 25.4 ± 4.7 0.381
Diabetes at Baseline, n (%) 57 (24%) 44 (27%) 0.595
Recipient Age, Mean Years ± SD 54 ± 12 58 ± 11 0.001
Donor Age, Mean Years ± SD 31 ± 12 33 ± 13 0.115

CONCLUSION: Cardiac rehabilitation is associated with less development of CAV at 5-years. Further study into the mechanisms of this finding is to be pursued.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Kittleson M, Patel J, Rafiei M, Osborne A, Chang D, Czer L, Kobashigawa J. Role of Cardiac Rehabilitation after Heart Transplantation in the Reduction of Cardiac Allograft Vasculopathy, The [abstract]. Am J Transplant. 2013; 13 (suppl 5). https://atcmeetingabstracts.com/abstract/role-of-cardiac-rehabilitation-after-heart-transplantation-in-the-reduction-of-cardiac-allograft-vasculopathy-the/. Accessed January 18, 2021.

« Back to 2013 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.