ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Revisiting the Second Kidney Transplant in Children

C. Bell, J. Angelo, J. Bynon, R. Swinford

Department of Pediatric Nephrology &
Hypertension, University of Texas Health Science Center at Houston (UTHSC), Medical School, Houston, TX
Division of Immunology &
Organ Transplant, UTHSC, Medical School, Houston, TX

Meeting: 2013 American Transplant Congress

Abstract number: C1426

Related Abstracts
  • Geographic Variation May Explain Disparities in Pediatric Waiting List Times for Hispanic Children
  • Neurocognitive Profile of Children Born to Kidney Transplant Recipients Mothers

Purpose: To describe the path of children after primary transplant (tpx) failure and determine factors influencing the probability and wait times for second tpx.

Methods: Retrospective review of SRTR/UNOS tpx records from 1987-2010 in children who received a single-organ kidney tpx when < 20 yrs.

Results: Of 7,248 primary tpx failures in children (median age 14), nearly half (47%) were not re-transplanted. Mortality of re-transplanted (4%) was similar to those on wait list (3%) and double those not re-listed (8%). The majority (59%) of 3,716 second tpx occurred within first 2 yrs of re-listing; 39% re-transplanted within 12m and 24% re-transplanted within 6m(Fig1a). The odds of receiving second tpx decreased 16% for each additional year on wait list (p<.001). Of those waiting >5 years, less than half (46%) received a second tpx(Fig1b).

Living donor (LD) and cadaveric donor (CD) sequence significantly influenced wait times to second tpx and combined wait times to primary and second tpx. Of those who received a second tpx, LD-LD and CD-CD had the shortest and longest wait times, respectively. While expected LD-CD had longer wait for second tpx compared to CD-LD, surprisingly combined primary and second wait times were significantly longer for LD-CD vs CD-LD(Fig2). Other factors that significantly increased wait times to second tpx were older age at primary tpx, non-white race, and primary or secondary PRA ≥ 80% (p<.05).

Conclusions: Many children have difficulty receiving a second tpx after primary failure. The likelihood of re-transplantation is strongly affected by time on wait list and donor source sequence. This study confirms the use of LD in secondary tpx after CD in primary tpx as a viable option in children.

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Bell C, Angelo J, Bynon J, Swinford R. Revisiting the Second Kidney Transplant in Children [abstract]. Am J Transplant. 2013; 13 (suppl 5). https://atcmeetingabstracts.com/abstract/revisiting-the-second-kidney-transplant-in-children/. Accessed April 22, 2021.

« Back to 2013 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Live Related Kidney Transplant Experience in Abuja, Nigeria – First Eight Cases Ever.
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.