Session Time: 3:15pm-4:00pm
Presentation Time: 3:30pm-4:00pm
*Purpose: Resilience is the capacity to adapt to or recover from adverse experiences. Our objective was to measure resilience in waitlisted, adult heart transplant candidates using the validated Connor-Davidson Resilience Scale (RISC-10) and examine scores as a predictor of transplant-related outcomes.
*Methods: Candidates on the heart transplant waiting list at 1 of 3 US transplant centers were mailed prospective RISC-10 questionnaires between 9/16/2015 to 3/28/2019. After 3 recruitment attempts, non-responders were declared non-participators. Enrollees received annual surveys until transplant, death, or delisting. Post-transplant surveys were collected between 3-12 months following transplant. Additional demographic and transplant data were abstracted from the electronic health record. Statistical analyses included Chi-square or Kruskal-Wallis, Wilcoxon, and Age-adjusted Poisson regression models. P-values <0.05 were significant.
*Results: Participation was 48% (N=195). A majority were male (68%), white (85%), and married (72%). Baseline RISC-10 scores averaged 31.9±6, which is comparable to expected population norms (32.1±5.8). However, 34 participants (17%) had scores ≥ 1 SD below expected norms. Baseline RISC-10 scores did not differ by sex, race, marital status, education, hospitalization status, or functional measures (% predicted VO2 max, Karnofsky, or 6 minute walking distance). RISC-10 scores did not change while waitlisted (mean change of 0.5±5.3; p=0.38; N=76). During the study, 92 participants were transplanted, 7 were delisted due to deterioration, and 14 died while on the waitlist. Nine patients died post-transplant. Post-transplant RISC-10 scores increased by a mean of 0.9±5.7; p=0.22; N=67. Baseline RISC-10 scores were not associated with waitlist or post-transplant death, delisting, or rejection but were associated with length of stay (LOS) (adjusted relative risk 0.987; p=0.01).
*Conclusions: In heart transplant candidates, resilience was comparable to population norms. However, 1 in 5 patients had low resilience suggesting select patients may benefit from resilience training interventions. RISC-10 scores did not change during listing or after transplant. RISC-10 was not associated with death, delisting, or rejection but was associated with LOS.
To cite this abstract in AMA style:Bui YT, Yip DS, Hardaway BW, Dunlay SM, Jowsey-Gregoire S, Benzo R, Daly RC, Hathcock MA, Thompson K, Kennedy CC. Resilience in Heart Transplant Candidates [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/resilience-in-heart-transplant-candidates/. Accessed April 15, 2021.
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