Renal Allograft Survival after Dual Kidney Transplantation is at Least as Favorable as Outcome after Expanded Criteria Donor Kidney Transplantation
1SUNY Downstate Medical Center, Brooklyn, NY, 2Department of Surgery,, USU-Walter Reed Uniformed Services University, Bethesda, MD, 3USU-Walter Reed Uniformed Services University, Bethesda, MD
Meeting: 2019 American Transplant Congress
Abstract number: B149
Keywords: Donors, marginal, Graft survival, Kidney, Outcome
Session Information
Session Name: Poster Session B: Kidney Donor Selection / Management Issues
Session Type: Poster Session
Date: Sunday, June 2, 2019
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall C & D
*Purpose: Dual kidney transplantation (DKT) is the implantation of two adult kidneys from a marginal donor into a single recipient. DKT may play an important role in decreasing discard rates and reducing wait time. Herein, we aim to assess the trends and outcomes in DKT recipients.
*Methods: Using United Network for Organ Sharing (UNOS) data, DKT recipients from 2008 to 2017 were included. Using Kaplan-Meier and Cox proportional hazards adjusting for covariates, renal allograft survival rates were computed.
*Results: A total of 921 DKT recipients were identified. Only 92 (37.7%) transplant centers performed DKT, of which the majority of DKTs were performed in 2 transplant centers. The number of DKTs decreased from 515 between yrs. 2008-2012 to 406 in the yrs. 2013-2017. Overall, renal allograft survival was lower in DKT as compared to standard criteria donor (SCD) but significantly higher in DKT recipients as compared to expanded criteria donor (ECD) renal transplant recipients (p<0.0001). Figure 1 shows the renal allograft survival between the three groups: DKT, SCD and ECD renal transplant recipients in the overall cohort. However, for renal transplant recipients from 2013 -2017 only, the difference in renal allograft survival was similar between DKT and ECD renal transplant recipients.
*Conclusions: Based on its favorable outcome results, DKT needs to be maximized to further decrease the discard rates of marginal kidneys. The most recent decrease in DKT is probably the result of inadequate reimbursement and should be addressed by our transplant societies.
To cite this abstract in AMA style:
Brar A, Sattar M, Gruessner A, Jindal RM, Nee R, Gruessner R, Salifu M. Renal Allograft Survival after Dual Kidney Transplantation is at Least as Favorable as Outcome after Expanded Criteria Donor Kidney Transplantation [abstract]. Am J Transplant. 2019; 19 (suppl 3). https://atcmeetingabstracts.com/abstract/renal-allograft-survival-after-dual-kidney-transplantation-is-at-least-as-favorable-as-outcome-after-expanded-criteria-donor-kidney-transplantation/. Accessed May 9, 2025.« Back to 2019 American Transplant Congress