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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Pulmonary Function Tests and Liver Transplantation

    D. Reino1, P. Martinez2, K. Robichaux3, M. Gosselin4, S. Mohammed3, J. Buggs1, A. Kumar5

    1Transplant Surgery, Tampa General Hospital, Tampa, FL, 2University of Miami, Miami, FL, 3University of South Florida, Tampa, FL, 4University of Tampa, Tampa, FL, 5Morsani College of Medicine, University of South Florida, Tampa, FL

    *Purpose: Liver transplant recipients have a high risk of developing postoperative pulmonary complications. Pulmonary function tests (PFTs) are expensive and often incapable of predicting patients…
  • 2022 American Transplant Congress

    Impact of Total Parenteral Nutrition on Donor Kidneys During Oxygenated Preservation at 22ºC Ex Vivo

    P. Luke1, A. Jackson2, A. Ruthirakanthan2, S. Juriasingani2, M. Levine1, L. Jiang2, R. Patel2, M. Richard-Mohamed1, S. Forrest1, A. Sener1, R. N. Bhattacharjee1

    1London Health Sciences Centre, London, ON, Canada, 2Western University, London, ON, Canada

    *Purpose: Recent studies have shown that ex vivo preservation at 37 º C can reduce kidney injury compared to current clinical practice. However, to mitigate…
  • 2022 American Transplant Congress

    Outcomes After Deceased Donor Kidney Transplantation Utilizing Kidney Allografts with Marginal Perfusion Parameters: A Single-Center Experience

    P. N. Chotai1, A. Logan2, F. Siddiqui3, A. Schenk4, G. Bumgardner5, G. L. Brock2, A. El-Hinnawi5, A. Rajab6, K. Washburn7, N. Singh2

    1Division of Transplantation, Department of General Surgery, The Ohio State University Wexner Medical Center, Columbus, OH, 2The Ohio State University Wexner Medical Center, Columbus, OH, 3Ohio State University, Bloomfield, NJ, 4Ohio State University Wexner Medical Center, Bexley, OH, 5Ohio State University, Columbus, OH, 6Ohio State University Wexner Medical Center, Columbus, OH, 7The Ohio State University, Columbus, OH

    *Purpose: To study outcomes of deceased donor kidney transplantation (DDKT) in recipients of kidney allografts with poor perfusion parameters.*Methods: This is a retrospective, single center…
  • 2022 American Transplant Congress

    De Novo DSA in the Setting of Stable Allograft Function is a Benign Finding

    R. J. Knight, E. A. Graviss, D. T. Nguyen, T. N. Eagar, S. G. Yi, H. Podder, M. Hobeika, R. McMillan, A. O. Gaber

    Houston Methodist Hospital, Houston, TX

    *Purpose: We sought to determine the long-term outcome of renal allografts that developed de novo DSA (dnDSA) in the setting of stable renal function.*Methods: A…
  • 2022 American Transplant Congress

    Association Between CT Measurements of Body Composition Before Liver Transplantation and Post-Transplantation Outcomes

    Y. Liu1, O. Shafaat1, K. Jackson1, J. Motter1, B. Boyarsky1, M. Latif1, F. Yuan1, E. King1, A. Zaheer1, R. Summers2, D. Segev1, M. McAdams-DeMarco1, C. Weiss1

    1Johns Hopkins University, Baltimore, MD, 2NIH Clinical Center, Bethesda, MD

    *Purpose: Various methods exist for measuring body composition using computed tomography (CT) scans; however, it is unclear which components best predict post-liver transplantation (LT) outcomes.…
  • 2022 American Transplant Congress

    Antibody Response to 3-Dose SARS-CoV-2 mRNA Vaccination in Pediatric Solid Organ Transplant Recipients

    C. X. Qin1, S. R. Auerbach2, O. Charnaya1, L. A. Danziger-Isakov3, N. H. Ebel4, A. G. Feldman2, E. K. Hsu5, J. McAteer1, S. Mohammad6, E. R. Perito7, A. M. Thomas1, T. P. Chiang1, J. M. Garonzik-Wang1, D. L. Segev1, D. B. Mogul1

    1Johns Hopkins University, Baltimore, MD, 2University of Colorado, Aurora, CO, 3University of Cincinnati, Cincinnati, OH, 4Stanford University, Palo Alto, CA, 5University of Washington, Seattle, WA, 6Northwestern University, Chicago, IL, 7University of California San Francisco, San Francisco, CA

    *Purpose: We report the immunogenicity and safety of a third BNT162b2 vaccine in pediatric solid organ transplant recipients (pSOTRs).*Methods: Samples from pSOTRs (12-18 years) enrolled…
  • 2022 American Transplant Congress

    An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion Injury in a Murine Model

    S. Duarte, A. Kobayashi, V. Boominathan, A. Kwiatkowski, J. Simonovich, A. Wanchoo, G. Hudalla, B. Keselowsky, A. Zarrinpar

    University of Florida, Gainesville, FL

    *Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor liver grafts. However, despite its…
  • 2022 American Transplant Congress

    Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience

    A. Altheaby1, R. Algain2, R. Salem2, A. Alotaibi2, K. Owaidah2, M. Tawahri1, M. Shaheen3, Z. Arabi4

    1Nephrology, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 2Internal Medicine, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia, 3King Saud Bin Abdulaziz for Health Sciences, Riyadh, Saudi Arabia, 4Renal Transplant, King Abdulaziz Medical City-NGHA, Riyadh, Saudi Arabia

    *Purpose: The expanding supply-demand mismatch between organs available for transplantation and patients in need led to the growth of transplant tourism. In our study, we…
  • 2022 American Transplant Congress

    Dual Therapy with Esculin and Erythropoietin Attenuates Renal Ischemia-Reperfusion Injury via P2x7 Receptor and Nlrp3 Inflammasome Inhibition, and Pi3k/akt Activation

    E. Hafiz1, W. H. El-Maadawy2, M. Hassan3, M. H. Badawy4, S. Eldahshan4, A. AbuSeada5

    1Clinical Research Laboratory Department, Theodor Bilharz Research Institute, Giza, Egypt, 2Pharmacology Department, Theodor Bilharz Research Institute, Giza, Egypt, 3Immunology Department, Theodor Bilharz Research Institute, Giza, Egypt, 4Urology Department, Theodor Bilharz Research Institute, Giza, Egypt, 5Anesthesia Department, Theodor Bilharz Research Institute, Giza, Egypt

    *Purpose: Renal ischemia/reperfusion (RI/R) is an inevitable condition during renal transplantation with critical clinical outcomes. Accordingly, effective therapies are crucially required.*Methods: In this study, the…
  • 2022 American Transplant Congress

    Improving Efficiency in Kidney Distribution: A Comparison of UNet Deceased Donor Criteria to Actual Kidney Acceptance Practices

    L. B. Zeiser, J. Ruck, D. Segev, A. Massie

    Johns Hopkins University, Baltimore, MD

    *Purpose: Efficient utilization of UNet deceased-donor criteria could help streamline kidney allocation by reducing the number of unwanted offers made to transplant centers. We compared…
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