Abstracts Archive - Page 812 of 1683 - ATC Abstracts

2018 American Transplant Congress
Preoperative Patient Education to Improve the Inpatient Experience for Living Donors
K. Ventura, K. Sigafus.
Transplant Department, Hospital of the University of Pennsylvania, Philadelphia, PA.
Purpose: Although the number of living organ donors is small, their altruistic sacrifice requires a dedicated approach to meet their unique needs. Living donors (LD)…
2018 American Transplant Congress
Four Eyes Are Better Than Two: Improving Laboratory Report Quality Control
S. Dionne,² K. Klama,² H. Rashid,² A. Niedzinski.²
¹Quality Assurance, LABS, Inc., Centennial, CO; ²Infectious Disease, LABS, Inc., Philadelphia, PA.
Background: Our STAT donor-screening lab implemented a new LIMS that is used to manage patient orders, testing and reporting. We intentionally customized the LIMS to…
2018 American Transplant Congress
Evaluating Transplant Quality Staffing Models via a National Survey
M. Cook, I. Feurer, L. Smith, S. Rega, E. Zavala.
Vanderbilt Transplant Center, VUMC, Nashville, TN.
The 2007 CMS Final Rule included expectations that transplant centers implement data-driven quality assessment and performance improvement (QAPI) programs. Currently, insufficient data exists to guide…
2018 American Transplant Congress
The Providers Can't Let Go! An Analysis of an RN Driven Tacrolimus Dose Adjustment Protocol
Z. Elmaasarani, C. Mardis, L. Gylten, J. Fleming, H. Meadows, N. Patel, C. Perez, D. Taber, V. Rao, V. Rohan, P. Baliga, D. Dubay, N. Pilch.
MUSC, Charleston.
Introduction: Tacrolimus (FK) dose adjustment is frequently performed by non-MD staff. Standard protocols to evaluate the ability of non-providers to maintain pts within a goal…
2018 American Transplant Congress
After Action Review of Emergency Preparedness for “Hurricane Harvey” for LifeGift Houston
R. Wood, K. Myer.
LifeGift, Houston, TX.
ProblemReview and evaluate a Texas based OPO's response to Hurricane Harvey. The storm hit the Texas Coast on Aug. 25, 2017 and flooded the area…
2018 American Transplant Congress
Lymph Node Reprogramming: Microparticle Delivery of Immune Signals to Induce Tolerance and Prolong Allograft Survival
Y. Xiong,¹ L. Tostanoski,² C. Jewell,² J. Bromberg.¹
¹UMB, MD; ²UMCP, MD.
Introduction: Microparticle (MP) loaded with peptide antigen plus other immune signals and delivered directly into lymph nodes (LN) can result in either pro-inflammatory or anti-inflammatory…
2018 American Transplant Congress
Long-Term Nonhuman Primate Renal Allograft Survival without Ongoing Immunosuppression in Recipients of Delayed Donor Bone Marrow Transplantation
K. Hotta, T. Oura, A. Dehnadi, M. Matsunami, I. Rosales, R. Smith, R. Colvin, A. Cosimi, T. Kawai.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Background: We have previously reported induction of renal allograft tolerance in nonhuman primates following an initial post-transplant period of conventional immunosuppression (IS) using a nonmyeloablative…
2018 American Transplant Congress
Mitochondrial Membrane Permeability Plays a Critical Role for Endothelial Cell Necroptosis and Cardiac Allograft Rejection
I. Gan, J. Jiang, D. Lian, X. Huang, W. Liu, A. Haig, A. Jevnikar, Z. Zhang.
Matthew Mailing Centre for Translational Transplant Studies, University of Western Ontario, London, ON, Canada; Multi Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; Pathology and Laboratory Medicine, University of Western Ontario, London, ON, Canada; Medicine, University of Western Ontario, London, ON, Canada.
Background: Transplant injury is invariably associated with programmed cell death resulting in delayed graft function and organ rejection. We were the first to describe receptor-interacting…
2018 American Transplant Congress
ABO Tolerance after Treatment of Infant or Adult Mice with MHC-Matched A-Expressing Blood Cells
B. Motyka,¹ J. Fersovich,¹ B. Lamarche,¹ M. Sosniuk,¹ I. Adam,¹ J. Pearcey,¹ K. Tao,¹ C. Cairo,² P. Cowan,³ L. West.¹
¹Dept Pediatrics, Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, Canada; ²Dept Chemistry, University of Alberta, Edmonton, Canada; ³St Vincent's Hospital, Melbourne, Australia.
Purpose: ABO-incompatible heart transplantation (ABOi HTx) is safe during infancy and allows increased donor access. Post-ABOi HTx B cell tolerance develops to donor blood group…
2018 American Transplant Congress
Biomaterial-Based Localized and Controlled Delivery of Tofacitinib to Actuate Enhanced Costimulation Blockade and Promote Long-Term Transplant Survival
G. Raimondi,¹ P. Majumder,² V. Ivanova,¹ X. Calderon-Colon,³ A. Mirdad,¹ M. Iglesias Lozano,¹ W. Lee,¹ G. Brandacher,¹ J. Schneider,² J. Patrone.³
¹Johns Hopkins School of Medicine, Baltimore; ²National Cancer Institute, Frederick; ³Johns Hopkins Applied Physics Laboratory, Laurel.
Complications from long-term use of calcineurin inhibitors remain a major issue for transplant patients and alternative therapies are highly needed. We investigated two innovative drug…