Abstracts Archive - Page 771 of 1683 - ATC Abstracts

2018 American Transplant Congress
Induction Therapy with Low-Dose Rituximab Could Be a Risk Factor of BKV Associated Nephropathy in Kidney Transplant Recipients
R. Murakami,¹ D. Nagawa,¹ M. Nakata,¹ I. Narita,¹ T. Fujita,¹ M. Shimada,¹ N. Nakamura,¹ H. Tomita,¹ S. Hatakeyama,² T. Yoneyama,² Y. Hashimoto,² T. Koie,² C. Ohyama.²
¹Nephrology, Hirosaki University, Hirosaki, Japan; ²Urology, Hirosaki University, Hirosaki, Japan.
Background.In kidney transplant recipients, BK polyoma virus (BKV) infection is common and serious complication that could lead to graft loss. Previous studies reported that 30-40%…
2018 American Transplant Congress
Higher Concordance in the Incidence of DGF and Post-Transplant BKV Infection among Recipients Receiving Mate Kidneys from the Same Deceased Donor: A Paired Deceased Donor Kidney Transplant Analysis
K. Venkatesh,¹ C. Wu,¹ C. Puttarajappa,¹ R. Mehta,¹ P. Sood,¹ A. Tevar,² S. Hariharan.¹
¹Nephrology Division, Univ of Pittsburgh Medical Center, Pittsburgh, PA; ²Transplant Surgery, Univ of Pittsburgh Medical Center, Pittsburgh, PA.
Background: This study was undertaken to explore the degree to which donor variables impact rates of DGF, post-transplant CMV and BKV infections using a paired…
2018 American Transplant Congress
Prospective Study of Switching from Tacrolimus to Low-Dose Cyclosporine A Preserving Allograft Function in BK Virus-Associated Nephropathy
G. Huang, X. Chen, S. Yang, C. Wang.
Organ Transplant Center/Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Background: Tacrolimus(Tac) -mycophenolic acid compared to cyclosporine is an independent risk factor for BK virus-associated nephropathy (BKVAN). Cyclosporine A (CsA) can inhibit BKV replication in…
2018 American Transplant Congress
mTOR Inhibitor Based Immunosuppression Regimens Are Not Associated with Lower Risk for BK Infection
R. Daloul,¹ R. Pelletier,² A. Rajab,² G. Bumgardner,² M. Alebrahim,² C. Akateh,³ K. Washburn,² A. El-Hinnawi.²
¹Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH; ²Transplant Surgery, The Ohio State University Wexner Medical Center, Columbus, OH; ³Surgery, The Ohio State University Wexner Medical Center, Columbus, OH.
Introduction: BK virus continues to be a significant post-transplant complication with increasing incidence in the current era of potent immunosuppression. Mammalian target of rapamycin inhibitors…
2018 American Transplant Congress
HLA Mismatching and cPRA Do Not Affect BK Viremia and Nephropathy Risk in Kidney Transplantation: A Retrospective Analysis
B. Suleiman, S. Saleh, W. Hassan, K. Wang, A. Maibam, A. Karim, A. Hines, X. Mei, A. El-Husseini, M. Yaseen, V. Cornea, A. Castellanos, R. Gedaly, T. Waid.
Nephrology, University of Kentucky, Lexington, KY.
Introduction:Nephropathy from BK virus is a significant complication of kidney transplantation and occurs following a period of viremia. Patients who are HLA mismatched and more…
2018 American Transplant Congress
Multiplexed Immunofluorescence to Investigate the Immune Response to BK Virus in Pediatric Kidney Transplant Recipients
C. Fajardo,¹ P. Grimm,¹ N. Kambham,² G. Nolan,³ N. Samusik,³ J. Maltzman.³
¹Pediatrics, Stanford, Stanford, CA; ²Pathology, Stanford, Stanford, CA; ³Immunology, Stanford, Stanford, CA.
Background: BK virus-associated nephropathy (BKVN) is a significant complication in renal transplantation that leads to allograft dysfunction or failure. BKV is thought to reactivate as…
2018 American Transplant Congress
Role of BK Virus-Specific T Cell Immune Monitoring for BK Virus-Associated Nephropathy in Kidney Transplant Recipients
J. Bruminhent,¹ S. Srisala,² C. Klinmalai,³ S. Pinsai,¹ S. Watcharananan,¹ S. Kantachuvessiri,⁵ S. Hongeng,⁴ N. Apiwattanakul.³
¹Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; ²Research Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; ³Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; ⁴Division of Hematology and Oncology, Department of Pediatrics Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; ⁵Division of Nephrology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Background: Reduced immunosuppression in a key therapy for BK virus (BKV)-associated nephropathy (BKVAN) in kidney transplant (KT) recipients. A study of immune monitoring against BKV…
2018 American Transplant Congress
Association between Donor/Recipient BK Viral Serostatus and Risk of BK Viraemia Post-Transplantation
S. Chong,¹ C. Atkinson,² N. Banga,¹ M. Harber,¹ M. Reeves,² C. Magee.¹
¹Royal Free London NHS Foundation Trust, London, United Kingdom; ²Department of Virology, University College London, London, United Kingdom.
IntroductionThe development of BK viraemia, and subsequently, BK nephropathy is a potentially devastating event associated with kidney transplant loss. In contrast to other clinically important…
2018 American Transplant Congress
Prevalence, Risk Factors and Impact of BK Viremia on Kidney Transplantation: Single Center Experience
W. Hassan, A. El-Husseini, B. Suleiman, K. Wang, M. Yaseen, A. Maibam, A. Karim, A. Hines, A. Castellanos, V. Cornea, X. Mei, R. Gedaly, T. Waid.
Nephrology, University of Kentucky, Lexington, KY.
Introduction: BK viremia (BKV) is an emerging problem in renal transplantation. The risk factors and the impact of BKV on renal allograft and patient survival…
2018 American Transplant Congress
Prediction of BK Viremia by Urine BK Viral Load in Renal Transplant Patients: BK Viral Load Results in Paired Urine and Plasma Samples
K. Madden,¹ C. Janitell,² S. Yang.²
¹Pathology, University of New Mexico, Albuquerque, NM; ²Microbiology, Tricore Reference Laboratories, Albuquerque, NM.
BK virus (BKV) associated nephropathy (BKVAN) affects up to 10% of renal transplant recipients, causing graft failure without intervention; a presumptive BKVAN diagnosis is made…