2018 American Transplant Congress
Death-Censored Graft Failure (DCGF) Post Kidney Transplant (KTx) is Usually the Result of Rapid Loss of Function after Periods of Stability
Late graft dysfunction leading to clinically indicated transplant biopsy (KTxBx) is a better predictor of subsequent DCGF than baseline data and early post-transplant events (Gaston…2018 American Transplant Congress
Impact of De Novo DSA Development and Management on Kidney Transplant Outcomes
Multiple studies have shown that development of donor specific antibodies (DSAs) can have a negative impact on renal allograft outcomes resulting in decreased renal function,…2018 American Transplant Congress
Competing Risk Analysis in Renal Allograft Survival: A New Perspective to an Old Problem
1Medicine, Mayo Clinic, Rochester, MN; 2Biostatistics, Mayo Clinic, Rochester, MN.
Background:Patient and graft survival after kidney transplant (KTX) is often estimated by Kaplan-Meier censoring for competing factors, e.g.death-censored graft survival. However when the competing factor…2018 American Transplant Congress
A Novel, Dose-Adjusted Tacrolimus Intrapatient Variability Model Identifies High-Risk Kidney Transplant Recipients Better Than Existing Methodologies
Astellas Pharma Global Development, Inc., Northbrook.
Intrapatient variability (IPV) of tacrolimus trough concentration (TTC) is a risk factor for inferior transplant outcomes. However, assessing IPV is problematic, relying on fixed dose…2018 American Transplant Congress
Association of Physical Function and Survival in Elderly Renal Transplant Recipients
Background: There is a significant increase in the number of older renal transplant recipients in the United States. Physical function (PF) may impact mortality in…2018 American Transplant Congress
C4d Staining and Graft Survival in Renal Transplant Recipients
Nephrology and Transplant, Henry Ford Hospital, Detroit, MI.
Introduction: C4d staining in peritubular capillaries strongly correlates with presence of acute or chronic antibody mediated rejection (AMR). Data on the significance of variable C4d…2018 American Transplant Congress
Characteristics and Outcomes of Kidney Transplant Recipients with More Than 25 Years of a Functioning Graft
University of Wisconsin, Madison.
Background: There is limited information on clinical characteristics and outcomes of kidney transplant recipients (KTRs) with more than 25 years of graft survival.Methods: We addressed…2018 American Transplant Congress
Outcome Analysis of Renal Re-Transplantation Compared to a Matched Control Group of First Transplantation
Background: 15% of our renal transplant program is re-transplantation (Tx2). We aimed to know if Tx2 has a higher risk than first transplantation (Tx1) and…2018 American Transplant Congress
Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial
Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…2018 American Transplant Congress
Ischemia-Free Liver Transplantation for Fatty Liver Grafts in Human
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
BACKGROUND&AIMS: Fatty liver diseases have led to a continuous increase of available donor livers containing fat. Fatty liver grafts were identified as an independent risk…
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