Abstracts Archive - Page 766 of 1683 - ATC Abstracts

2018 American Transplant Congress
Association between Everolimus Trough Levels, Onset of Related Adverse Events, and Treatment Discontinuation after Liver Transplantation: 24-Month Results from the H2304 Study
J. Fung,¹ F. Saliba,¹ H. Schlitt,¹ G. Junge,² K. McCague,³ D. Patel,³ M. Charlton.¹
¹H2304 Study Group, Chicago; ²Novartis Pharma AG, Basel, Switzerland; ³Novartis Pharmaceuticals Corporation, East Hanover.
Purpose: Evaluation of mammalian target of rapamycin inhibitor (mTORi)-related adverse events (AEs) and drug trough levels (C0) at onset may aid their management in liver…
2018 American Transplant Congress
Post-Hoc Analysis of Everolimus Trough Levels around the Onset of Related Adverse Events and Treatment Discontinuation in De Novo Kidney Transplant Recipients from the US92 Study
F. Shihab,¹ Y. Qazi,¹ V. Peddi,¹ D. Shaffer,¹ K. McCague,² D. Patel,² S. Mulgaonkar.¹
¹US92 Study Group, Salt Lake City; ²Novartis Pharmaceutical Corporation, East Hanover.
Purpose: Around 30%-50% of kidney transplant recipients (KTR) on sirolimus discontinue treatment due to drug-related adverse events (AE) and ~23% on everolimus (EVR) discontinue treatment…
2018 American Transplant Congress
Metabolic Regulation of Neuropeptides Induces Weight Loss and is Linked to Prolongation of Allograft Survival
M. Quante,^1,2 T. Heinbokel,¹ K. Minami,¹ Y. Nian,¹ A. Elkhal,¹ S. Tullius.¹
¹Transplant Surgery Research Lab, Brigham and Women's Hospital, Boston, MA; ²Department of General, Visceral and Transplant Surgery, Tuebingen Unversity Hospital, Tuebingen, Germany.
Obesity has become a common comorbidity among transplant recipients that is linked to inferior transplant outcome through far-reaching effects on metabolism, inflammation and immunity. Increasingly,…
2018 American Transplant Congress
Application of RNA-Seq Derived Diagnostic Algorithms of T-Cell Mediated Kidney Rejection (TCMR) to DNA Microarray-Based Gene Expression Datasets
Z. Wang,¹ L. Pan,² Z. Lyu,² P. Liu,³ G. Tseng,³ P. Randhawa.¹
¹Department of Pathology, The Thomas E Starzl Transplantation Institute, University of Pittsburgh, School of Medicine, Pittsburgh, PA; ²Department of Nephrology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China; ³Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA.
Recent years have seen the development of DNA microarray based tools for the diagnosis of TCMR using fresh frozen tissue. This study has accomplished the…
2018 American Transplant Congress
Self-Reported Post-Surgical Pain Following Living Kidney Donation
A. Fleishman,¹ J. Schold,² P. Morrissey,³ J. Whiting,⁴ J. Vella,⁴ L. Kayler,⁵ D. Katz,⁶ J. Jones,⁶ B. Kaplan,⁷ M. Pavlakis,¹ D. Mandelbrot,⁸ J. Rodrigue.¹
¹Beth Israel Deaconess Medical Center, Boston; ²Cleveland Clinic, Boston; ³Rhode Island Hospital, Providence; ⁴Maine Medical Center, Portland; ⁵University of Buffalo, Buffalo; ⁶University of Iowa, Iowa City; ⁷May Clinic, Scottsdale; ⁸University of Wisconsin, Madison.
The Kidney Donor Outcomes Cohort (KDOC) is an NIH-funded observational cohort study evaluating outcomes in living kidney donors (LKDs) at 6 US centers. LKDs completed…
2018 American Transplant Congress
Chronic Changes on Time Zero Living Donor Allograft Biopsy Portraits Worse Donor Renal Function
A. Nishio-Lucar,¹ J. Murphy,² A. Sites,³ H. Cathro,² A. Doyle,¹ K. Warburton,¹ A. Agarwal.⁴
¹Medicine, University of Virginia, Charlottesville, VA; ²Pathology, University of Virginia, Charlottesville, VA; ³Transplant Services, University of Virginia, Charlottesville, VA; ⁴Surgery, University of Virginia, Charlottesville, VA.
The prognostic ability of zero hour biopsy (ZHB) in renal allografts has not been fully elucidated. ZHB utility predicting living kidney donor (LKD) renal recovery…
2018 American Transplant Congress
The Impact of Duration on Dialysis on the Pre-Transplant Allosensitization According to Panel Reactive Antibody Levels
Y. Jung,¹ D. Kim,¹ J. Lee,¹ S. Song,² J. Lee,³ B. Kim,⁴ J. Lee,¹ S. Kim,¹ M. Kim,¹ S. Kim,¹ Y. Kim,¹ K. Huh.¹
¹Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; ²Department of Surgery, College of Medicine, Ewha Women's University, Seoul, Republic of Korea; ³Department of Surgery, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea; ⁴Departments of Nephrology, Yonsei University College of Medicine, Seoul, Republic of Korea.
Purpose : Presensitization to human leukocyte antigen(HLA) is one of the most important barriers to overcome in the field of renal transplantation. Due to the…
2018 American Transplant Congress
Spigelius' Line Incision as a Successful Route to Extract the Kidney during Retroperitoneal Laparoscopic Live-Donor Nephrectomy
J. Qiu, G. Chen, Z. Wu, C. Wang, L. Chen.
Organ Transplantation, The First Affiliated Hospital of Sun Yet-sen University, Guangzhou, Guangdong, China.
To introduce the advantages, incision designing methods and surgical procedures of spigelius' line incision in retroperitoneal laparoscopic living donor nephrectomy.Methods: The clinical data of 114…
2018 American Transplant Congress
Effects of Medication Education Pilot Program in Living versus Deceased Donor Kidney Transplant Recipients.
N. Sulejmani, H. Albanna, B. Summers, A. Jantz, R. Prashar, A. Patel.
Henry Ford Transplant Institute, Detroit, MI.
Purpose: Medication adherence is crucial for transplant recipients as non-adherence can result in increased risk of rejection and graft loss. Early education prior to transplant…
2018 American Transplant Congress
South Asian and Muslim Canadian Patients Are Less Likely to Receive Living Donor Kidney Transplant Offers Compared to Caucasian, Non-Muslim Patients
A. Ali,¹ A. Ayub,¹ C. Richardson,¹ N. Edwards,¹ T. Ahmed,¹ M. Novak,^2,3 I. Mucsi.¹
¹Multi-Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada; ²Centre for Mental Health, University Health Network, Toronto, ON, Canada; ³Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Background:No studies have assessed whether Muslim Canadians face barriers to accessing LDKT. We explored how frequently Muslim or South Asian patients with and stage kidney…