ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Rapid Formalin-Fixed Deceased Donor Kidney Biopsy Protocol – A Proof Of Concept

    M. R. Marvin1, G. Chen2, A. Kotru1, C. Koo1, P. Sanghi3, M. Moritz4, J. Clarke4, R. Hasz4

    1Transplant, Geisinger Medical Center, Danville, PA, 2Pathology, Geisinger Medical Center, Danville, PA, 3Transplant Nephrology, Geisinger Medical Center, Danville, PA, 4Gift of Life Donor Program, Philadelphia, PA

    *Purpose: Reducing kidney discard is a major priority for the transplant community. While frozen section biopsies are the current standard, they are fraught with technical…
  • 2022 American Transplant Congress

    Comparison of Cardiovascular Events by Different Types of Lipid-Lowering Drugs in Kidney Transplant Recipients

    S. Bae1, J. Ahn2, M. A. Schnitzler3, K. Lentine4, D. Segev1, M. McAdams-DeMarco1

    1Johns Hopkins University, Baltimore, MD, 2SOM, Johns Hopkins University, Baltimore, MD, 3Surgery, Saint Louis University, St. Louis, MO, 4Saint Louis University, St. Louis, MO

    *Purpose: Lipid-lowering drugs, notably statins, are one of the most widely prescribed drug classes in kidney transplant (KT) recipients. These drugs have substantially different mechanisms…
  • 2022 American Transplant Congress

    Donor Terminal Creatinine – Does It Matter?

    V. G. Menon, Y. Wert, W. Hoffman, D. Ladie, M. Singh, M. Waybill, H. Yang

    UPMC, Harrisburg, PA

    *Purpose: When assessing deceased donor kidneys, the transplantation team studies several donor variables including creatinine. A creatinine that is elevated immediately prior to procurement can…
  • 2022 American Transplant Congress

    Decellularized Human Pancreatic Extracellular Matrix-Based Physiomimetic Microenvironment for Human Islet Culture

    A. Asthana1, D. Chaimov1, R. Tamburrini2, S. J. Walker3, G. Orlando1

    1Wake Forest Baptist Medical Center, Winston-Salem, NC, 2University of Wisconsin Hospital and Clinics, Madison, WI, 3Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC

    *Purpose: Maintenance of human islet viability and function ex vivo can be a significant bottleneck for both regenerative medicine as well as tissue engineering applications.…
  • 2022 American Transplant Congress

    Superoxide in Cardiac Allografts from Donors After Circulatory Death

    M. Urban1, T. Bruett2, K. F. Duncan1, N. W. Markin3, M. M. Chacon3, M. C. Zimmerman4

    1Department of Surgery. Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, NE, 2College of Medicine. Department of Cellular and Integtrative Physiology., University of Nebraska Medical Center, Omaha, NE, 3Department of Anesthesiology, University of Nebraska Medical Center, Omaha, NE, 4Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Omaha, NE

    *Purpose: Quality of cardiac allografts from donors after circulatory death (DCD) is adversely impacted by warm ischemia and subsequent reperfusion during organ resuscitation. Post-transplant myocardial…
  • 2022 American Transplant Congress

    Benefit of Kidney Transplantation for Post Lung Transplantation Renal Failure: Need for Priority Allocation

    S. Karhadkar1, A. Gregor1, K. Jonathan1, J. Dawes1, A. Diamond2, K. Wirshup1, A. DiCarlo1

    1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA

    *Purpose: Nephrotoxicity is a major side effect of thoracic transplantation. Many patients will eventually require renal transplantation (KAL) to manage their developing ESRD. Recently, simultaneous…
  • 2022 American Transplant Congress

    Increased Regulatory T-cells in Tumor Microenvironment is Associated with Hepatocellular Carcinoma Differentiation in Patients Undergoing Liver Transplantation

    G. Orozco1, R. Gedaly2, L. Turcios2, F. Marti2

    1Surgery, University of Kentucky, Lexington, KY, 2UKHC, Lexington, KY

    *Purpose: Tumor-infiltrating lymphocytes are an essential component of the tumor microenvironment. The balance between cytotoxic effector T cells and immunosuppressive regulatory T cells is critical…
  • 2022 American Transplant Congress

    Role of Circulating Tumour Cells in the Management of the Liver Transplant Patient with Hepatocellular Carcinoma

    F. Villalba1, F. Alconchel2, L. Sáenz3, M. Sánchez-Lorencio1, D. Ferreras2, P. Cascales2, F. Sánchez-Bueno2, R. Robles2, P. Ramírez2

    1IMIB-Virgen de la Arrixaca, Murcia, Spain, 2Surgery and Organ Transplantation, Virgen de la Arrixaca University Hospital (IMIB-Virgen de la Arrixaca), Murcia, Spain, 3Rafael Méndez Hospital, Lorca, Spain

    *Purpose: For hepatocellular carcinoma (HCC), liver transplantation (LT) is considered a curative treatment, however, more than 10% of transplant recipients have recurrences within the first…
  • 2022 American Transplant Congress

    Barriers and Facilitators to Care for Patients with Failed Kidney Transplants

    A. Huml1, K. Berg2, A. Perzynski2, C. Sullivan2, A. Sehgal2

    1Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, 2Population Health Research Institute, The MetroHealth System, Cleveland, OH

    *Purpose: To understand the barriers and facilitators to care for patients with failed kidney transplants from the perspective of providers.*Methods: Qualitative study employed focus groups…
  • 2022 American Transplant Congress

    Comparing The Immunologic Responses Between Kidney Transplant Recipients Receiving Standard Immunosuppression And CNI Reduction After Two Doses Of ChAdOx-1 And A Booster Dose BNT162b2

    S. Phirom1, T. Kitrungphaiboon2, W. Jantarabenjakul2, Y. Avihingsanon2, W. Prasithsirikul3, J. Vanichanan4, P. Hansasuta5, N. Townamchai6

    1Nephrology division, Department of medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 2King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 3Bamrasnaradura infectious disease institute, Bangkok, Thailand, 4Infectious diseases, Department of medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 5Department of Microbiology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 6Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand

    *Purpose: Immunosuppression can impair immunological responses after vaccination in kidney transplant recipients (KTR). However, little is known about the effect of the booster dose of…
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