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American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Assessment Of Glomerular Filtration Rate Among Lung Transplant Candidates

    S. Akkina1, S. Hou2, D. Jain Arwindekar2, A. Desai2

    1Loyola University Medical Center, Maywood, IL, 2Medicine, Loyola University Medical Center, Maywood, IL

    *Purpose: Assessment of kidney function in lung transplant candidates is difficult due to cachexia prior to transplant. Measured glomerular filtration rate (GFR) studies are useful…
  • 2019 American Transplant Congress

    The Molecular Features of Chronic Lung Allograft Dysfunction (CLAD) in Transbronchial and Endobronchial Mucosa Biopsies

    M. D. Parkes1, K. M. Halloran1, J. Chang2, P. F. Halloran and the INTERLUNG study group1

    1University of Alberta, Edmonton, AB, Canada, 2ATAGC, University of Alberta, Edmonton, AB, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD), the major long-term problem in lung transplantation, requires new strategies for prevention and management. However, CLAD is infrequently diagnosed…
  • 2019 American Transplant Congress

    Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients

    F. J. Marco Canosa1, K. Brizendine2, H. Hassouna3

    1Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 3Infectious Disease, Spectrum Health Infectious Disease, Grand Rapids, MI

    *Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…
  • 2019 American Transplant Congress

    Simulation of DSA-Free Lung Allocation

    M. Skeans1, J. Pyke1, K. Audette1, R. Lehman2, K. Uccellini2, K. M. Chan3, E. D. Lease4, R. Daly5, M. Valapour6

    1SRTR, Minneapolis, MN, 2OPTN, Richmond, VA, 3Univ. of Michigan, Ann Arbor, MI, 4Univ. of WA, Seattle, WA, 5Mayo Clinic, Rochester, MN, 6Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: In November 2017, the OPTN Executive Committee removed donation service area (DSA) as the first unit of adult donor lung allocation, replacing it with…
  • 2019 American Transplant Congress

    Effect of Enoxaparin Prophylaxis on Early VTE Post Lung Transplant

    S. Marshall1, K. Tsveybel1, S. Boukedes1, P. Burkett2, R. Chepuri2, A. Coppolino3, M. Divo2, S. El-Chemaly2, S. Keller2, J. Kennedy2, H. Mallidi3, G. Mody3, T. Thaniyavarn2, A. Trindade2, K. Townsend1, H. Goldberg2

    1Lung Transplant, Brigham & Women's Hospital, Boston, MA, 2Pulmonary Division, Brigham & Women's Hospital, Boston, MA, 3Thoracic Surgery, Brigham & Women's Hospital, Boston, MA

    *Purpose: Thromboembolic complications are common post-transplant leading to significant morbidity. We instituted early enoxaparin prophylaxis (ppx) in lung transplant recipients (LTR) due to an observed…
  • 2019 American Transplant Congress

    Lung Transplantation in the Elderly Patients with Multi-Comorbidities

    N. Shigemura, Y. Toyoda

    Temple University Health System / Lewis Katz School of Medicine, Philadelphia, PA

    *Purpose: Recently there is an outstanding steadily increase in elderly patients above 70 years old who are referred to our center as potential candidates for…
  • 2019 American Transplant Congress

    Simulation vs. Reality: 250NM as First Unit of Lung Allocation

    M. Skeans1, J. Pyke1, C. Lehr2, R. Lehman3, K. Uccellini3, K. M. Chan4, E. D. Lease5, R. Daly6, M. Valapour2

    1SRTR, Minneapolis, MN, 2Cleveland Clinic Foundation, Cleveland, OH, 3OPTN, Richmond, VA, 4Univ. of Michigan, Ann Arbor, MI, 5Univ. of WA, Seattle, WA, 6Mayo Clinic, Rochester, MN

    *Purpose: In November 2017, the OPTN Executive Committee removed donation service area as the first unit of donor allocation, replacing it with a circle of…
  • 2019 American Transplant Congress

    Synergistic Effect of HLA Eplet Mismatch Load and CMV Viremia on Clinical Antibody-Mediated Rejection in Lung Transplantation

    Y. Im1, S. Yeramaneni2, Y. Yim3, J. Dodderer4, M. Askar1, H. J. Huang5

    1Baylor University Medical Center, Dallas, TX, 2Baylor Scott & White Health, Dallas, TX, 3Ross University School of Medicine, Portsmouth, Dominica, 4Texas Tech University Health Sciences Center, El Paso, TX, 5Houston Methodist Hospital, Houston, TX

    *Purpose: De novo donor specific antibodies (dnDSA) occur in up to 50% of lung transplant (LUTX) recipients within one year and are associated with increased…
  • 2019 American Transplant Congress

    Comparison of Basiliximab and Alemtuzumab for Lung Transplant Induction

    S. Mietz1, D. Roe2, E. Lushin1, E. Anderson1, C. Hage2

    1Pharmacy, Indiana University Health, Indianapolis, IN, 2Pulmonary Critical Care, Indiana University Health, Indianapolis, IN

    *Purpose: Compare alemtuzumab and basiliximab used for lung transplant in terms of rejection, CLAD, and mortality.*Methods: A retrospective review of lung transplants performed between 2010…
  • 2019 American Transplant Congress

    ­Pediatric Heart and Lung Graft Loss during the “High-Risk Age Window”

    J. Long1, J. Motter1, K. R. Jackson1, M. Kosztowski1, B. Orandi2, X. Luo1, K. Van Arendonk3, A. Massie1, E. Bush1, R. S. Higgins1, D. L. Segev1, J. M. Garonzik-Wang1

    1Johns Hopkins School of Medicine, Baltimore, MD, 2University Of Alabama at Birmingham, Birmingham, AL, 3Children’s Hospital of Wisconsin-Milwaukee Campus, Milwaukee, WI

    *Purpose: Pediatric kidney transplant recipients experience a high-risk age window of increased graft loss during late adolescence and early adulthood (17-24 years), termed emerging adulthood.…
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