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American Transplant Congress abstracts

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  • 2019 American Transplant Congress

    Biliary Atresia Patients Receiving Liver Transplantation Reflect Changing Birth Demographics in the United States between 1987-2018

    R. Sindhi, K. Soltys, G. Mazariegos, G. Bond, A. Khanna, P. McKiernan

    Childrens Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    *Purpose: To review the multi-center US experience with liver transplantation (LT) for Biliary Atresia (BA)*Methods: We reviewed LT outcomes in children with BA in the…
  • 2019 American Transplant Congress

    Living Donor vs. Deceased Donor Liver Transplantation for Pediatric Patients with Metabolic Liver Disease

    G. Gu, Q. Xia

    Renji Hospital, Shanghai, China

    *Purpose: Liver transplantation has been accepted as the appropriate treatment option for pediatric metabolic liver disease and the most common methods used are LDLT and…
  • 2019 American Transplant Congress

    Metabolic Liver Transplant: A Single Cooperative 2002-2017

    N. Yazigi1, K. Chapman2

    1Transplantation, MedStar Georgetown University Hospital, Washigton, DC, 2Transplantation, Children's National Rare Disease Institute, Washington, DC

    *Purpose: Liver transplant (LT) can increase quality and quantity of life for patients with inherited metabolic diseases (IMDs) who suffer severe and unpredictable complications despite…
  • 2019 American Transplant Congress

    Liver Transplantation in Children with Type 1 and Type 2 Autoimmune Hepatitis

    I. G. Roepe, J. A. Goss, T. Miloh

    Department of Student Affairs, Baylor College of Medicine, Houston, TX

    *Purpose: Autoimmune Hepatitis (AIH) can be defined as type 1 and type 2 based on autoantibodies. Liver transplant (LT) may be indicated for chronic liver…
  • 2019 American Transplant Congress

    Independent Risk Factors for Discard of Pediatric Liver Allografts

    T. H. Malik1, J. Goss2, N. T. Galvan2, M. L. Kueht II2, A. Rana3

    1Department of Student Affairs, Baylor College of Medicine, Houston, TX, 2Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX, 3Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX

    *Purpose: The aim of this study is to identify risk factors available at the time of initial DonorNet offer to predict discard of pediatric liver…
  • 2019 American Transplant Congress

    Obesity Induced IL-18 Production Impairs FOXP3+ Treg Function and Increases Risk of Primary Graft Dysfunction in Lung Transplant Recipients

    W. W. Hancock1, T. Zhang1, U. H. Beier1, A. Samanta1, R. Han1, L. Wang1, J. Jiao1, J. M. Diamond2, D. S. Wilkes3, D. J. Lederer4, R. A. Simmons2, J. D. Christie2, T. Akimova2

    1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3University of Virginia, Charlottesville, VA, 4Columbia University, New York, NY

    *Purpose: Lung transplantation is a life-saving treatment for terminal lung diseases but long-term outcomes are poor, beginning with possible development of primary graft disease (PGD)…
  • 2019 American Transplant Congress

    Correlation between Gene Expression and Histology in Transbronchial Lung Transplant Biopsies

    B. Adam, K. Du, S. Rotich, M. Mengel

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Transbronchial lung transplant biopsies (TBBx) are limited by non-specific histologic lesions and suboptimal interobserver reproducibility. Gene expression offers a potentially more precise, objective and…
  • 2019 American Transplant Congress

    Impact of the 2013 Change in Definition of Increased Risk Donors on Lung Transplant Outcomes

    C. J. Lehr1, R. Lopez2, S. Arrigain2, J. D. Schold2, M. Valapour1

    1Respiratory Institute, Cleveland Clinic, Cleveland, OH, 2Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH

    *Purpose: The definition for donors at “increased risk” for human immunodeficiency virus (HIV), hepatitis B (HBV), and hepatitis C (HCV) was updated in 2013 from…
  • 2019 American Transplant Congress

    Molecular Features of Rejection in Endobronchial Mucosa Biopsies

    M. D. Parkes, K. M. Halloran, J. Chang, P. F. Halloran and The INTERLUNG Study Group

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Mucosal biopsies are safer and easier to collect than transbronchial biopsies (TBB) but cannot be assessed histologically for lung rejection. Reliable assessment would change…
  • 2019 American Transplant Congress

    Oral Ribavirin Therapy for Respiratory Syncytial Virus (RSV) in Lung Transplant Recipients: The Impact of Policy Implementation on Cost and Appropriate Use

    B. Berak, N. Sulejmani, A. Jantz, T. Larson, S. Davis, B. Summers

    Henry Ford Hospital, Detroit, MI

    *Purpose: RSV is a leading cause of viral infections in lung transplant recipients and is associated with significant morbidity and mortality. While the role of…
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