ATC Abstracts

American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee

    L. Danziger-Isakov1, J. D. Goldman1, A. Wooley1, S. Pouch1, A. Agarwal1, G. Berry1, K. Dunn1, S. Ho1, M. Kittleson1, D. H. Lee1, D. Levine1, C. Marboe1, G. Marklin1, R. Razonable1, S. Taimur1, H. Te1, C. Fox2, C. Jett2, S. Booker2, D. Klassen2, R. LaHoz1

    1OPTN, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
  • 2022 American Transplant Congress

    Reduction of Discharge Opioid Prescriptions After Kidney Transplantation: A Quality Improvement Project

    A. W. Rogers, E. Rizk, J. T. Swan, S. G. Yi, M. Hobeika, R. R. McMillan, J. C. Krisl, H. Podder, A. O. Gaber, R. J. Knight

    Houston Methodist Hospital, Houston, TX

    *Purpose: Opioid use after kidney transplant has been linked to poorer outcomes, and unused prescriptions can lead to potential misuse. Historical prescribing practice at our…
  • 2022 American Transplant Congress

    Understanding Transplant Awareness in Pre-Kidney Transplant Recipients – Role of Surgeon Visit

    G. Defelice, H. Harrington, M. Ratcliff, D. Moravec, E. Wands, A. Sauviac, A. Paramesh, A. Vijay

    Tulane University School of Medicine, New Orleans, LA

    *Purpose: Education for pre-Kidney Transplant recipient candidates aims to improve their knowledge and understanding about the transplant process, outcomes and potential complications and facilitate adjustment…
  • 2022 American Transplant Congress

    Single Cell RNA Sequencing Identifies Primarily Terminal Effector and Exhausted CD8+T Cells in Chronically Rejected Human Kidney Allografts

    S. G. Yi1, D. Zou1, Y. Dai2, Z. Zhao2, W. Chen1, A. Gaber1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX, 2School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX

    *Purpose: Chronic renal allograft rejection often leads to irreversible damage, despite intensification of immunosuppression (ISN). T cell phenotypes in this clinical setting are not well…
  • 2022 American Transplant Congress

    Higher Proinflammatory Cytokines Are Associated with Increased Antibody Titer After a Third Dose of SARS-CoV-2 Vaccine in Solid Organ Transplant Recipients

    A. H. Karaba1, X. Zhu1, S. E. Benner1, O. Akinde1, Y. Eby1, K. H. Wang1, S. Saraf2, J. M. Garonzik-Wang3, S. L. Klein1, J. R. Bailey1, A. L. Cox1, J. N. Blankson1, C. M. Durand1, D. L. Segev1, W. A. Werbel1, A. A. Tobian1

    1Johns Hopkins University, Baltimore, MD, 2National Institute of Allergy and Infectious Diseases, Bethesda, MD, 3University of Wisconsin School of Medicine and Health, Madison, WI

    *Purpose: Solid organ transplant recipients (SOTRs) are at increased risk for severe COVID-19 and exhibit lower antibody responses to SARS-CoV-2 vaccines. This study aimed to…
  • 2022 American Transplant Congress

    Dynamic Changes and Roles of Specialized Pro-resolving Lipid Meditators in the Initiation and Resolution Process of Lung Ischemia-Reperfusion Injury in Rats

    H. Oda1, S. Tanaka1, M. Shinohara2, Y. Morimura1, Y. Yokoyama1, H. Kayawake1, Y. Yamada1, A. Ohsumi1, D. Nakajima1, H. Date1

    1Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto City, Japan, 2The Integrated Center for Mass Spectrometry, Kobe University Graduate School of Medicine, Kobe City, Japan

    *Purpose: Lung ischemia-reperfusion injury (IRI) is one of the significant complications after lung transplantation, which is a form of acute lung injury by robust inflammation.…
  • 2022 American Transplant Congress

    Impact of Cold Ischemia Times on 1 Year Kidney Transplant Outcomes

    T. Fletchinger, L. Burdine

    Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR

    *Purpose: Recent organ allocation changes have increased travel and subsequent cold ischemia times (CIT) of kidney allografts. We sought to investigate the impact of prolonged…
  • 2022 American Transplant Congress

    What If Only Days After Dialysis Counted Towards Kidney Candidates’ Qualified Waiting Times?

    G. R. Vece, K. Lindblad, M. Stuart, B. Carrico, D. Stewart, D. Klassen, S. Diallo

    Research, United Network for Organ Sharing, Richmond, VA

    *Purpose: Current kidney policy allows patients who have not yet initiated dialysis to qualify for allocation priority based on the time since a recorded eGFR…
  • 2022 American Transplant Congress

    Impact of Maintaining Blood Pressure Goals on Graft Function After Kidney Transplant

    D. Majmundar, A. DiCarlo, S. Karhadkar, A. Diamond, K. Mohrien, P. Szczesniak

    Temple University Hospital, Philadelphia, PA

    *Purpose: Impaired graft function following kidney transplant impacts short- and long-term patient outcomes. Proper management of systolic blood pressure (SBP) in the immediate post-operative period…
  • 2022 American Transplant Congress

    Estrogen Receptor Beta Deletion is Protective in Renal Ischemia Reperfusion Injury but Pharmacologic Inhibition of Estrogen Receptor Beta is Not

    C. OBrien1, P. Hernandez2, S. Concors2, Z. Wang1, G. Ge1, W. Hancock3, M. Levine2

    1Surgery, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Childrens Hospital of Philadelphia, Philadelphia, PA

    *Purpose: Renal Ischemia Reperfusion Injury (IRI) contributes substantially to delayed graft function (DGF) in kidney transplantation. Prior work by our group has shown lower rates…
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