ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Marginal Livers Have Excellent Outcomes in Pediatric Patients with Metabolic Liver Disease

    M. MacConmara, C. Feizpour, D. Desai, S. Hanish, P. Vagefi, A. Aqul, C. S. Hwang

    UT Southwestern, Dallas, TX

    *Purpose: Pediatric patients with metabolic diseases are listed so that livers are preferentially allocated to them, having the option of receiving a very high quality…
  • 2020 American Transplant Congress

    Liver Transplantation in Obese Recipients: Post-Transplant Weight Gain and Outcomes

    D. Soma1, Y. Park1, P. Mihaylov1, B. Ekser1, M. S. Ghabril2, M. A. Lacerda2, N. Chalasani2, R. S. Mangus1, C. A. Kubal1

    1Transplant Division, Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, 2Transplant Hepatology, Division of Gastroenterology, Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Non-alcoholic fatty liver disease is now the most common cause of end-stage liver disease necessitating orthotopic liver transplantation (OLT) in the United States. Several…
  • 2020 American Transplant Congress

    Statin Use May Be Associated with Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients

    A. Perez Cortes Villalobos, F. Foroutan, S. Davoudi, T. Martinu, J. Tikkanen, L. Singer, S. Keshavjee, S. Husain

    University Health Network, Toronto, ON, Canada

    *Purpose: Statins are competitive inhibitors of HMG-CoA reductase, that catalyses the conversion of HMG-CoA to mevalonate, which is involved in the synthesis of cholesterol in…
  • 2020 American Transplant Congress

    Proinflammatory Cytokines Including IL-18 Correlate with Cytomegalovirus DNAemia in Solid Organ Transplant Recipients

    A. H. Karaba, A. Figueroa, S. C. Ray, R. K. Avery, A. L. Cox

    Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD

    *Purpose: Human cytomegalovirus (CMV) is a common immunomodulatory virus that still causes significant morbidity and mortality in solid organ transplant (SOT) recipients despite prophylaxis. Cytokines…
  • 2020 American Transplant Congress

    Perioperative Management and Post-Liver Transplantation Outcomes in Methylmalonic Acidemia, Propionic Acidemia and Urea Cycle Disorders: 20 Years’ Experience

    P. Vuong1, N. Ebel2, A. Brubaker1, P. Than1, C. Baker2, A. Pedroza1, K. Taylor1, S. Conlon1, D. Romero1, G. Enns2, C. Esquivel1

    1Surgery, Stanford University, Palo Alto, CA, 2Pediatrics, Stanford University, Palo Alto, CA

    *Purpose: To examine long-term outcomes after liver transplantation for organic acidemias and urea cycle defects at our center which utilizes standardized pre-, peri- and post-operative…
  • 2020 American Transplant Congress

    Brincidofovir for Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid Organ Transplant Recipients

    J. Londeree1, R. Garro1, R. Romero2, R. George1, P. Winterberg1, R. Liverman3, A. Serluco3, S. Shin1, I. Yildirim4

    1Pediatric Nephrology, Emory, Atlanta, GA, 2Pediatric Hepatology and Gastroenterology, Emory, Atlanta, GA, 3Pharmacy, Children's Healthcare of Atlanta, Atlanta, GA, 4Pediatric Infectious Disease, Emory, Atlanta, GA

    *Purpose: Brincidofovir (BCV) is an investigational antiviral drug with potency against Human Adenovirus (HAdV). We describe four cases of disseminated HAdV infection treated with (BCV)…
  • 2020 American Transplant Congress

    Absolute Lymphocyte Count: Is There a “Safety Corridor?”

    G. Elhelou1, B. Lahr2, R. Razonable3

    1Medicine, Division of Infectious Diseases and Global Medicine, University of Florida, Gainesville, FL, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Medicine, Division of Infectious Disease, Mayo Clinic, Rochester, MN

    *Purpose: Iatrogenic suppression of T cells is intended to prevent rejection after solid organ transplantation (SOT). This is complicated by opportunistic infections, most notably cytomegalovirus…
  • 2020 American Transplant Congress

    Pneumocystis Pneumonia Occurrence and Prophylaxis Duration in Kidney Transplant Recipients According to Perioperative Treatment with Rituximab

    Y. Ko, Y. Kim, D. Han, H. Kwon

    Department of Surgery, Division of Kidney and Pancreas Transplant, AMC, Seoul, Korea, Republic of

    *Purpose: Pneumocystis pneumonia (PCP) is a life-threatening fungal infection that can occur in kidney transplantation (KT) recipients. A growing number of KT recipients are receiving…
  • 2020 American Transplant Congress

    Pharmacokinetics of Maribavir in Subjects with Moderate Hepatic Impairment

    I. H. Song1, K. Ilic2, J. Wu3

    1Quantitative Clinical Pharmacology, Shire, a Takeda Company, Lexington, MA, 2Rare Disease TAU, Shire, a Takeda Company, Lexington, MA, 3Biostat, Shire, a Takeda Company, Lexington, MA

    *Purpose: Maribavir, an investigational agent for cytomegalovirus (CMV) infection in transplant recipients, has received Breakthrough Therapy Designation. Maribavir is metabolized primarily in the liver through…
  • 2020 American Transplant Congress

    Duration of Pre-Transplant Abstinence Does Not Predict Severe Relapses of Alcohol Abuse in High-Risk Alcoholic Liver Transplant Recipients

    W. H. Kitchens

    Emory Transplant Center, Atlanta, GA

    *Purpose: The traditional requirement of >6 months pre-transplant sobriety for liver transplant recipients has been challenged by emerging literature, but risk factors for post-transplant recidivism…
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