Abstracts Archive - Page 516 of 1683 - ATC Abstracts

2020 American Transplant Congress
Brincidofovir for Treatment of Disseminated Human Adenovirus Infection in Pediatric Solid Organ Transplant Recipients
J. Londeree¹, R. Garro¹, R. Romero², R. George¹, P. Winterberg¹, R. Liverman³, A. Serluco³, S. Shin¹, I. Yildirim⁴
¹Pediatric Nephrology, Emory, Atlanta, GA, ²Pediatric Hepatology and Gastroenterology, Emory, Atlanta, GA, ³Pharmacy, Children's Healthcare of Atlanta, Atlanta, GA, ⁴Pediatric Infectious Disease, Emory, Atlanta, GA
*Purpose: Brincidofovir (BCV) is an investigational antiviral drug with potency against Human Adenovirus (HAdV). We describe four cases of disseminated HAdV infection treated with (BCV)…
2020 American Transplant Congress
Epidemiology of Cytomegalovirus (CMV) in Pediatric Solid Organ Transplant Recipients (SOTR) at Texas Children’s Hospital (TCH)
K. Valencia, K. Hosek, E. Moulton, F. Munoz, G. Demmler-Harrison, C. Bocchini
Baylor College of Medicine, Houston, TX
*Purpose: Despite widespread use of prevention strategies, CMV remains a common opportunistic infection in SOTR. Contemporary data regarding CMV in pediatric SOTR is limited. We…
2020 American Transplant Congress
Artificial Intelligence May Predicts Early Sepsis in Liver Transplantation
R. D. Kamaleswaran¹, R. Lowell Davis², J. D. Eason³, S. Sataphaty⁴, V. R. Mas⁵, D. Maluf³
¹Biostatistics, Emory, Atlanta, GA, ²Center for Biomedical Informatics & Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, ³Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, ⁴Sandra Atlas Bass Center for Liver Diseases & Transplantation, Northshore University Hospital/Northwell Health, NSHS, NY, ⁵Biostatistics, Emory, Atlanta, TN
*Purpose: Sepsis post liver transplantation is a frequent challenge impacting patient outcomes. We aimed to develop an artificial intelligence method to predict earlier the onset…
2020 American Transplant Congress
Proinflammatory Cytokines Including IL-18 Correlate with Cytomegalovirus DNAemia in Solid Organ Transplant Recipients
A. H. Karaba, A. Figueroa, S. C. Ray, R. K. Avery, A. L. Cox
Division of Infectious Diseases, Department of Medicine, Johns Hopkins University, Baltimore, MD
*Purpose: Human cytomegalovirus (CMV) is a common immunomodulatory virus that still causes significant morbidity and mortality in solid organ transplant (SOT) recipients despite prophylaxis. Cytokines…
2020 American Transplant Congress
A Liver Transplant Candidate with Above Average Conscientiousness is More Likely to Receive a Liver Transplant
O. Siddiqui¹, J. Lai², D. Peipert¹, T. Kaundinya¹, A. Daud¹, A. Hall¹, D. Ganger¹, R. Wong², C. Loftus¹, D. Mroczek¹, D. Ladner¹
¹Northwestern University, Chicago, IL, ²UCSF, San Francisco, CA
*Purpose: Liver transplant (LT) candidates are currently assessed in terms of their physical, social and mental capacity to take care of themselves and their grafts.…
2020 American Transplant Congress
Increased Level of Serum Cholesterol and Apoptosis Together Induces the Development of Liver Fibrosis and Early Allograft Loss
B. H. Ozdemir¹, G. Ozgun¹, E. H. Ayvazoglu Soy², N. Haberal¹, M. Haberal²
¹Pathology, Baskent University, Ankara, Turkey, ²Department of General Surgery, Division of Transplantation, Baskent University, Ankara, Turkey
*Purpose: Hypercholesterolemia (HC) induced oxidative stress known to facilitate apoptosis, steatosis, and TGF-β induced liver injury. Apoptosis, in turn, can trigger inflammation, and fibrosis. Apoptotic…
2020 American Transplant Congress
Evaluation Of Typical Renal Transplant Infections In Simultaneous Heart-kidney Transplant Recipients
E. J. Henricksen¹, U. Wang¹, R. Lee¹, R. Imai¹, A. Puing², A. Couture², A. Multani³, Y. Moayedi⁴, C. Lenihan⁵, K. K. Khush⁶, J. J. Teuteberg⁵
¹Pharmacy, Stanford Healthcare, Stanford, CA, ²Infectious Diseases and Geographic Medicine, Stanford University, Stanford, CA, ³Infectious Diseases, UCLA, Los Angeles, CA, ⁴Cardiology, University Health Network, Toronto, ON, Canada, ⁵Department of Medicine, Stanford University, Stanford, CA, ⁶Medicine, Stanford University, Stanford, CA
*Purpose: Simultaneous heart-kidney transplant (SHKT) is an increasingly utilized treatment for patients with end stage heart failure and advanced kidney disease. Data regarding infectious complications…
2020 American Transplant Congress
Incidence of Oropharyngeal and Esophageal Candidiasis in Adult Kidney Transplant Recipients Receiving Nystatin versus No Prophylaxis
L. Moreno¹, K. Klein¹, C. Long², R. Hall¹, J. Nelson¹
¹Pharmacotherapy and Pharmacy Services, Pharmacotherapy Division, University Health System, The University of Texas Health Science Center at San Antonio, The University of Texas at Austin, College of Pharmacy, San Antonio, TX, ²Pharmacotherapy and Pharmacy Services, Pharmacy Practice, University Health System, University of the Incarnate Word Feik School of Pharmacy, San Antonio, TX
*Purpose: The purpose of this study is to evaluate the need for nystatin prophylaxis for oropharyngeal (OPC) and esophageal Candidiasis (EC) in adult kidney transplant…
2020 American Transplant Congress
Solid Organ Transplantation Using Hepatitis C Virus Positive Donor Organs for Hepatitis C Virus Negative Recipients
T. Schiff, R. Bodin, I. Lee, K. Okumura, D. C. Wolf, A. Dhand, A. L. Gass, D. Spielvogel, G. Veillette, S. Nishida, D. Glicklich, K. Wolfe, T. Diflo, H. Sogawa
New York Medical College/ Westchester Medical Center, Valhalla, NY
*Purpose: To determine the effects of transplanting an HCV-positive solid organ to an uninfected patient who is on the transplant waiting list and might otherwise…
2020 American Transplant Congress
Impact and Outcomes of Primary Cytomegalovirus Infection in Seronegative Abdominal Solid Organ Transplant Recipients of Cytomegalovirus Unexposed Donors (D-/R-)
M. Jorgenson¹, M. Hillis¹, N. Friedlander¹, A. Gracon², D. Yang², G. Leverson², J. Smith², R. Redfield²
¹UWHC, Madison, WI, ²UWMF, Madison, WI
*Purpose: Primary cytomegalovirus infection (CMV) in high risk (D+/R-) abdominal solid organ transplant recipients (aSOTRs) is well described, however there is a paucity of literature…