Abstracts Archive - Page 485 of 1683 - ATC Abstracts

2020 American Transplant Congress
The Composite Molecular and Cellular Instability Score Identifies the Sub-Phenotypes of Histologically Stable Kidney Transplants
D. Rychkov
Department of Surgery, BCHSI, University of California San Francisco, San Francisco, CA
*Purpose: Recent molecular studies have highlighted the unrecognized burden of sub-clinical graft rejection of a histologically stable allograft, defined as transplants with absence of clinical…
2020 American Transplant Congress
Long Term Liver Transplant Survivors
M. Haberal¹, E. Ayvazoglu Soy¹, G. Moray¹, F. Ozcay², A. Torgay³
¹Department of General Surgery, Division of Transplantation, Baskent University, Ankara, Turkey, ²Pediatric Nephrology, Baskent University, Ankara, Turkey, ³Anaesthesia, Baskent University, Ankara, Turkey
*Purpose: Few reports mentioned about long term survey. In this study, we aimed to report the outcomes of our long term LT survivors (LTS).*Methods: Our…
2020 American Transplant Congress
The Plasma DdcfDNA Level Associates with the Pathological Characteristics in Renal Allograft
R. Wang, J. Shen, J. Wu, J. Chen
Kidney Disease Center, First Affiliated Hospital of Zhejiang University, Hangzhou, China
*Purpose: Donor-derived cell-free DNA (ddcfDNA) is a promising biomarker for monitoring the allograft health status, however, its relationship with the pathological characteristics is still elusive.*Methods:…
2020 American Transplant Congress
Metabolism Reprogramming During Conventional versus Ischemia-Free Liver Transplantation
Z. Guo¹, Z. Zhang¹, N. Gao¹, H. Zhang², X. He¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Sun Yat-sen University, Guangzhou, China
*Purpose: Our group has developed a novel transplant procedure called ischemia-free liver transplantation (IFLT), during which the liver can be procured, preserved and implanted without…
2020 American Transplant Congress
An Immune-Modulatory Strategy to Mitigate Hepatic Ischemia Reperfusion/Injury in a Murine Model
A. Kobayashi¹, A. Wanchoo², J. Simonovich², S. Duarte¹, V. Boominathan¹, S. Shrestha¹, G. Hudalla², B. Keselowsky²
¹Surgery, University of Florida, Gainesville, FL, ²Biomedical Engineering, University of Florida, Gainesville, FL
*Purpose: Hepatic ischemia/reperfusion injury (IRI) is the leading cause of early graft dysfunction and contributes to the shortage of donor organs. However, despite its obvious…
2020 American Transplant Congress
TGR5/Cathepsin E Signaling Regulates Macrophage Innate Immune Activation in the Sterile Inflammatory Liver Injury
H. Zhou, S. Zhou, Q. Wang, Z. Rao, X. Wang, L. Lu
The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: The hepatic proinflammatory response represents a major cause of liver ischemia and reperfusion (IR) injury. Although the role of plasma membrane-bound G protein-coupled bile…
2020 American Transplant Congress
Ifnar Signaling on Myeloid Cells Does Not Contribute to Costimulation Independent Transplant Rejection
J. Habib, D. Mathews, Y. Dong, A. Stephenson, A. Adams
Emory University, Atlanta, GA
*Purpose: Costimulation blockade (CoB) is a promising new strategy that provides a more targeted therapy with fewer side effects compared to traditional transplant immunosuppressants, leading…
2020 American Transplant Congress
Assessment of the Usefulness of Urine Signature to Differentiate Acute Rejection in a Prospective Kidney Transplantation Cohort
J. Seo¹, S. Jung², J. Moon², K. Jeong³, C. Kim⁴, B. Chung⁵, J. Park⁶, Y. Kim⁷, S. Lee²
¹Department of Core Research Laboratory, Medical Science Institute, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, ²Department of Internal Medicine, Division of Nephrology, Kyung Hee University Hospital at Gangdong, Seoul, Korea, Republic of, ³Department of Internal Medicine, Division of Nephrology, College of Medicine, Kyung Hee University, Seoul, Korea, Republic of, ⁴Department of Internal Medicine, Division of Nephrology, Kyung-pook National University School of Medicine, Daegu, Korea, Republic of, ⁵Department of Internal Medicine, Division of Nephrology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of, ⁶Department of Internal Medicine, Sungkyunkwan University, Samsung Hospital, College of Medicine, Seoul, Korea, Republic of, ⁷Department of Internal Medicine, Division of Nephrology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea, Republic of
*Purpose: Despite many biomarker studies in the field of transplantation, development and validation of noninvasive molecular assays to diagnose disease and monitor immune activity is…
2020 American Transplant Congress
Is Total Ischemic Time a Measure of OPTN Efficiency? Monitoring the Impact of Lung Allocation Policy on Ischemic Time
A. M. Placona¹, R. R. Goff¹, P. Shay², B. Carrico¹
¹United Network for Organ Sharing, Richmond, VA, ²Health Administration, Trinity University, San Antonio, TX
*Purpose: There is concern that the shift to circle based organ allocation policy may increase coordination costs. Within both public comment and the peer reviewed…
2020 American Transplant Congress
Basiliximab Induction in the Obese: One Size Does Fit All
A. D. Reticker¹, D. Choi¹, A. B. Lichvar¹, C. Kane², I. Tzvetanov³, E. Benedetti³, J. J. Benken¹
¹Pharmacy Practice, University of Illinois Hospital and Health Sciences System, Chicago, IL, ²Pharmacy, Northwestern Memorial Hospital, Chicago, IL, ³Surgery, University of Illinois Hospital and Health Sciences System, Chicago, IL
*Purpose: Surgical advancements allow more obese (BMI> 30 kg/m2) patients to receive a renal transplant. The original clinical and pharmacokinetic (PK) trials in transplantation immunosuppression…