2020 American Transplant Congress
Utility of dd-cfDNA in TCMR 1A and Borderline Allograft Rejection
*Purpose: The value of donor-derived cell-free DNA (dd-cfDNA, AlloSure) as a molecular marker for the early diagnosis of mild T-cell mediated rejection (Banff TCMR 1A…2020 American Transplant Congress
Noninvasive Detection of Subclinical Rejection in Urine RNA
*Purpose: Subclinical rejection may lead to long-term graft injury and can currently only be detected by repeated biopsies. A noninvasive method is needed to monitor…2020 American Transplant Congress
Activation of YAP Attenuates Hepatic Damage and Fibrosis in Liver Ischemia-Reperfusion Injury: From Bench to Bedside
1Dumont-UCLA Transplant Center, Los Angeles, CA, 2Shanghai Jiaotong University, Shanghai, China
*Purpose: Hepatic ischemia-reperfusion injury (IRI) is a major complication of hemorrhagic shock, liver resection and transplantation. YAP, the effector of Hippo pathway, is essential in…2020 American Transplant Congress
Should Steatotic Livers Be Transplanted Into Pediatric Recipients?
*Purpose: Although steatotic livers are frequently transplanted in the adult population, they are not commonly transplanted in pediatric recipients. We questioned if the outcomes of…2020 American Transplant Congress
Kidney Transplantation in Inherited Kidney Diseases
*Purpose: We aimed to evaluate the kidney transplant (KTx) recipients with inherited kidney diseases and investigate the causal genetic variants in recipients with undetermined etiology.*Methods:…2020 American Transplant Congress
The Use of Allosure Donor Derived Cell-Free DNA in a Community Based Kidney Transplant Program
Kidney Transplantation, Christiana Care Hospital, Newark, DE
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has emerged as a marker of kidney allograft injury. Beginning in 2019, the dd-cfDNA monitoring has been introduced as…2020 American Transplant Congress
Normothermic Machine Perfusion of Rat Liver: Comparing Two Perfusion Methods
Surgery, Washington University in St. Louis, St. Louis, MO
*Purpose: Isolated perfused rodent liver (IPRL) model has gained popularity in ex-vivo rat liver preservation and pharmacological intervention studies. Experimental conditions and system layouts vary…2020 American Transplant Congress
Ex-Vivo Perfusion with UW Cold Storage Solution Improves DCD Rat Liver Preservation
Surgery, Virginia Commonwealth University, Richmond, VA
*Purpose: The donor pool of livers can be expanded by the successful use of donor livers recovered under DCD conditions. It is assumed that perfusion…2020 American Transplant Congress
Caspase-1 Knockout Mice Have Increased Survival after Cold Ischemia in a Murine Kidney Transplant Model
*Purpose: Prolonged cold ischemia (CI) is a known risk factor for acute kidney injury (AKI) after kidney transplantation. However, the mechanism by which CI leads…2020 American Transplant Congress
New IGL-2 Perfusate in Liver HOPE Strategies
*Purpose: HOPE has shown to optimize graft liver preservation. However, the most used perfusion solutions as such as Belzer-MPS and its generics were initially for…
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