Abstracts Archive - Page 442 of 1683 - ATC Abstracts

2020 American Transplant Congress
Non-Invasive Near Infrared Fluorescence Based Monitoring of Macrophage Mediated Inflammation
H. Karagoz¹, N. Vettikattu¹, F. Selek¹, H. Kapucu¹, E. Goktas¹, L. Liu², Y. Kulahci¹, F. Zor¹, J. M. Janjic², V. S. Gorantla¹
¹Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, ²Department of Pharmaceuticals, Duquesne University, Pittsburgh, PA
*Purpose: Clinical assessments for inflammation and acute rejection (AR) require regular, invasive biopsies followed by staining protocols that provide static images of tissue. Despite such…
2020 American Transplant Congress
Stem Cell and Novel Neurotrophic Factors to Promote Functional Outcomes in Limb Transplantation
S. K. Salgar, J. Weiss, C. Phillips, E. Malin, V. Gorantla, J. Harding
Clinical Investigation, Madigan Army Medical Center, Tacoma, WA
*Purpose: Recently, transplantation of hand and face has become a new clinical specialty. The objective of this study was to determine whether adult Mesenchymal Stem…
2020 American Transplant Congress
Public Education about Vascular Composite Allotransplantation and Donation: A Content Analysis of Social Media and Educational Documents
S. Rasmussen¹, M. Henderson¹, N. Anderson², J. Uriarte², B. Doby¹, C. Cooney¹, D. Segev¹, G. Brandacher¹, E. Gordon²
¹Johns Hopkins, Baltimore, MD, ²Northwestern, Chicago, IL
*Purpose: : Consistent and accurate public messaging is crucial in organ donation and transplantation, particularly in the emerging field of vascular composite allotransplantation (VCA). Currently,…
2020 American Transplant Congress
B₂-Adrenergic Receptor Activation in Donor Cells Inhibits T Cell Trafficking in Vascularized Composite Tissue Allotransplants
M. Kim¹, D. Fisher¹, J. Loo¹, P. Bogner², U. Sharma³, J. Skitzki¹, E. Repasky⁴
¹Surgical Oncology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, ²Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, NY, ³Cardiology, University at Buffalo, Buffalo, NY, ⁴Immunology, Roswell Park Comprehensive Cancer Center, Buffalo, NY
*Purpose: Transplantation of faces, hands, and limbs using vascularized composite allotransplantation (VCA) has faced significant challenges hindering its routine implementation in the clinic. One critical…
2020 American Transplant Congress
Noninvasive Genotyping of Donor’s HLA in Kidney Transplant Patients by Target Capture Sequencing
T. Jiang, L. Shu, F. Liu, H. Liu, J. Ge
AlloDx, Shanghai; Suzhou, China
*Purpose: Antibody-mediated rejection (ABMR) is the major cause of kidney transplant failure, which requires donor-specific antibodies (DSA) for a definitive diagnosis based on Banff 2013.…
2020 American Transplant Congress
The Pro-Inflammatory Profile of Alcoholic Patients Increases Risk for Ischemia-Reperfusion Injury During Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, M. Rossetti¹, F. Li¹, J. Nevarez-Mejia¹, B. V. Naini¹, F. M. Kaldas², V. M. Groysberg¹, S. M. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski³, E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ²Department of Surgery, UCLA, Los Angeles, CA, ³Departments of Pathology and Laboratory Medicine and Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which triggers a pro-inflammatory immune response that can lower allograft survival in orthotopic liver transplant (OLT) patients. In…
2020 American Transplant Congress
Osmotic Nephropathy from a Non-Sucrose Based IVIG
S. Reddy, L. Kodali
Nephrology, Mayo Clinic, Phoenix, AZ
*Purpose: We present a case of acute renal failure and hyperkalemia due to osmotic nephropathy from a non-sucrose based IVIG infusion therapy.*Methods: A 67-year-old man…
2020 American Transplant Congress
Adenovirus Infection in Pediatric Liver Transplant Recipients: A Single Center Experience
S. Hassan¹, K. R. Mysore¹, M. E. Faraone², D. Cerminara³, K. Hosek⁴, E. Moulton⁵, C. Bocchini⁵, R. Sigereddi⁶, R. Ackah⁶, F. Muñoz⁵, A. Rana⁷, J. Goss⁷, D. H. Leung¹, T. Galvan⁷
¹Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, ²Department of Surgery, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, ³Department of Pharmacy, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, ⁴Outcomes and Impact Service, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, ⁵Department of Pediatrics, Infectious Diseases, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, ⁶Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, ⁷Michael E. DeBakey Department of Surgery, Division of Abdominal Transplantation, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX
*Purpose: Immunosuppression predisposes children to primary viral or latent infections after liver transplantation (LT). The impact of adenovirus infections on morbidity and mortality remains largely…
2020 American Transplant Congress
Chronic Active T-Cell Mediated Rejection is Variably Responsive to Immunosuppressive Therapy
V. Kung¹, M. Haas¹, M. Gillespie², E. Huang², R. Sandhu²
¹Pathology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Chronic active T cell-mediated rejection (CACMR) is a newly described variant of kidney allograft rejection associated with long-term graft loss. A key histologic feature…
2020 American Transplant Congress
What’s Lung Got to Do with It?: The Impact of the 2017 Lung Allocation Policy at a Single Organ Procurement Organization
A. J. Boyer, J. B. Nave, C. A. Hostetler, C. C. Muse, R. A. Squires, J. P. Orlowski
LifeShare Transplant Donor Services of Oklahoma, Oklahoma City, OK
*Purpose: To describe the impact of the lung allocation change on a single organ procurement organization (OPO). The allocation change took place on 11/24/2017 and…