Abstracts Archive - Page 440 of 1683 - ATC Abstracts

2020 American Transplant Congress
Pancreas Transplant in Patients Older Than 50: An Analysis of Outcomes and Immunosuppression
I. Booth¹, J. Casale¹, S. Freedman¹, B. Ravichandran¹, J. Scalea², A. Haririan², B. Masters¹
¹Pharmacy, University of Maryland Medical Center, Baltimore, MD, ²Medicine, University of Maryland Medical Center, Baltimore, MD
*Purpose: Pancreas transplant (PT) is the ideal therapy for many patients with diabetes and kidney failure. There are limited published data addressing the impact of…
2020 American Transplant Congress
The Use of Allosure Donor Derived Cell-Free DNA in a Community Based Kidney Transplant Program
V. Scantlebury, S. Gilibert, C. Sentman, H. Chang-DeGuzman, S. Swanson
Kidney Transplantation, Christiana Care Hospital, Newark, DE
*Purpose: Donor derived cell-free DNA (dd-cfDNA) has emerged as a marker of kidney allograft injury. Beginning in 2019, the dd-cfDNA monitoring has been introduced as…
2020 American Transplant Congress
Immunohistochemical and Molecular Detection of NK Cells in Kidney Allografts with Antibody Mediated Rejection
E. Farkash, J. Barnes, S. Anand
Pathology, University of Michigan, Ann Arbor, MI
*Purpose: Molecular signatures specific to Natural Killer (NK) cells are closely associated with antibody mediated rejection (AMR) in transplant biopsies. We have developed an immunohistochemical…
2020 American Transplant Congress
Novel Biomarkers for Post-Transplant Recurrent IgA Nephropathy
Y. Caliskan¹, B. Dirim², E. Aksoy², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: The aim of this study is to evaluate serum levels of galactose-deficient IgA1 (Gd-IgA1), advanced oxidation protein products (AOPP) and 4 tag single-nucleotide variants…
2020 American Transplant Congress
Microvascular Inflammation without DSA or C4d: An Orphan Category in Banff Classification with Intense Capillaritis and Cytotoxic T-Cell Infiltration
A. Buxeda¹, L. Llinàs-Mallol², J. Gimeno³, C. Arias-Cabrales¹, C. Burballa¹, D. Redondo-Pachón¹, D. Raïch-Regué², M. Pérez-Sáez¹, J. Pascual¹, M. Crespo¹
¹Nephrology Department, Hospital del Mar, Barcelona, Spain, ²Nephrology Department, IMIM - Institute Hospital del Mar for Medical Research, Barcelona, Spain, ³Pathology Department, Hospital del Mar, Barcelona, Spain
*Purpose: Antibody-mediated rejection (ABMR) associated with donor-specific HLA antibodies (DSA) is the leading cause of late allograft failure after kidney transplantation. Microvascular inflammation (MVI) without…
2020 American Transplant Congress
Utility of dd-cfDNA in TCMR 1A and Borderline Allograft Rejection
E. Stites¹, D. Kumar², O. Olaitan³, G. Gupta²
¹University of Colorado, Aurora, CA, ²Virginia Commonwealth University, Richmond, VA, ³Rush University, Chicago, CA
*Purpose: The value of donor-derived cell-free DNA (dd-cfDNA, AlloSure) as a molecular marker for the early diagnosis of mild T-cell mediated rejection (Banff TCMR 1A…
2020 American Transplant Congress
Femto Pulse Analysis of Exosome RNA from Plasma of Renal Transplant Patients Confirmed the Unique Benefits of Plasma Exosome for Messenger RNA (mRNA) Transcript Analysis
H. Zhang¹, K. Wong², S. C. Jordan³, D. Warzak², M. Toyoda¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA, ²Agilent Technologies, Inc., Ankeny, IA, ³Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Previously, we reported the feasibility of measuring the mRNA transcript levels of various genes in plasma exosomes of renal transplant patients for prediction of…
2020 American Transplant Congress
Kidney Transplantation in Inherited Kidney Diseases
Y. Caliskan¹, H. Yazici², R. Ouseph¹, Y. Ozluk³, H. Randall⁴, E. Demir², F. Savran Oguz⁵, A. Turkmen², M. S. Sever², K. Lentine¹
¹Division of Nephrology, Saint Louis University, Saint Louis, MO, ²Division of Nephrology, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Department of Pathology, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁴Center for Abdominal Transplantation, Saint Louis University, Saint Louis, MO, ⁵Department of Medical Biology, Istanbul Faculty of Medicine, Istanbul, Turkey
*Purpose: We aimed to evaluate the kidney transplant (KTx) recipients with inherited kidney diseases and investigate the causal genetic variants in recipients with undetermined etiology.*Methods:…
2020 American Transplant Congress
Mass Cytometry-Based Immunoprofiling as a Tool to Predict Rejection in a Large Cohort of Pediatric Transplant Recipients
M. Rao¹, J. T. Harden², M. Lapasaran², C. O. Esquivel³, O. M. Martinez², S. M. Krams²
¹Pediatrics, Stanford University, Palo Alto, CA, ²Stanford University School of Medicine, Stanford, CA, ³Surgery and Pediatrics, Stanford University School of Medicine, Stanford, CA
*Purpose: Rejection remains a serious problem in the pediatric transplant population. Early detection remains a challenge; furthermore, the changes in immune makeup which accompany rejection…
2020 American Transplant Congress
Should Steatotic Livers Be Transplanted Into Pediatric Recipients?
M. MacConmara, C. Feizpour, P. Vagefi, C. Ramirez, L. DeGregorio, C. S. Hwang
UT Southwestern, Dallas, TX
*Purpose: Although steatotic livers are frequently transplanted in the adult population, they are not commonly transplanted in pediatric recipients. We questioned if the outcomes of…