Abstracts Archive - Page 433 of 1683 - ATC Abstracts

2020 American Transplant Congress
Natural History of Tacrolimus Intrapatient Variability During the First Post-Transplant Year
A. D. Leino, J. L. Rodgers, K. M. Abuls
The Ohio State University Wexner Medical Center, Columbus, OH
*Purpose: High tacrolimus intrapatient variability (IPV) is associated with inferior outcomes in solid organ transplantation. Many evaluations of IPV empirically exclude the early post-transplant period…
2020 American Transplant Congress
Sodium Zirconium Cyclosilicate Use in Solid Organ Transplant Recipients and its Effect on Potassium and Immunosuppression
R. Winstead, M. Demehin, I. Yakubu, C. Song, A. Brown, M. Levy, L. Kamal, G. Gupta
VCU Health, Richmond, VA
*Purpose: Transplant recipients often suffer from hyperkalemia which can limit pharmacotherapy. The cause of hyperkalemia is often multifactorial including kidney dysfunction, calcineurin inhibitor use, and…
2020 American Transplant Congress
The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation
E. Van Loon, M. Coemans, A. Senev, D. Kuypers, M. Emonds, M. Naesens
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…
2020 American Transplant Congress
Pre-Transplant Pharmacogenetics Identifies CYP3A4 and CYP3A5 Heterogeneity among Caucasian Kidney Transplant Recipients
N. Oliver¹, L. Lindberg¹, S. LeCorchick¹, D. Morris¹, S. Anand¹, T. Srinivas²
¹Intermountain Medical Center, Murray, UT, ²University Hospitals Cleveland Medical Center, Cleveland, OH
*Purpose: Tacrolimus has always been dosed based on therapeutic drug monitoring, however pharmacogenomics is becoming increasingly more utilized in the era of precision based medicine…
2020 American Transplant Congress
Non-Invasive Near Infrared Fluorescence Based Monitoring of Macrophage Mediated Inflammation
H. Karagoz¹, N. Vettikattu¹, F. Selek¹, H. Kapucu¹, E. Goktas¹, L. Liu², Y. Kulahci¹, F. Zor¹, J. M. Janjic², V. S. Gorantla¹
¹Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, ²Department of Pharmaceuticals, Duquesne University, Pittsburgh, PA
*Purpose: Clinical assessments for inflammation and acute rejection (AR) require regular, invasive biopsies followed by staining protocols that provide static images of tissue. Despite such…
2020 American Transplant Congress
The Effects of Rivaroxaban and Apixaban on Tacrolimus Pharmacokinetics
A. C. Scheibner¹, C. Franco-Martinez¹, E. Kincaide¹, R. Hall¹, C. Long²
¹Pharmacotherapy Division, College of Pharmacy, The University of Texas at Austin, University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Feik School of Pharmacy, University of the Incarnate Word, University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX
*Purpose: To clarify the pharmacokinetic impact of rivaroxaban (RIVA) and apixaban (APIX) on tacrolimus (TAC) concentrations.*Methods: Solid organ transplant recipients 18-years or older who were…
2020 American Transplant Congress
The Scenario of Delayed Graft Function in Brazil
T. V. Sandes-Freitas¹, M. Mazzali², R. Manfro³, H. Tedesco-Silva⁴, L. Andrade⁵, V. Garcia⁶, E. Davi-Neto⁷, R. Esmeraldo⁸, C. Oliveira⁹, E. Lasmar¹⁰, R. Madeira¹¹, G. Ferreira¹², G. Meira¹³, F. Cavalcanti¹⁴, A. Bignelli¹⁵, D. Carvalho¹⁶, D. Pedroso¹⁷, L. Deboni¹⁸, A. Silva e Filho¹⁹, A. Vicari³, M. Sousa², .. on behalf of 'DGF multicêntrico' group²⁰
¹Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Brazil, ²HC/UNICAMP, Campinas, Brazil, ³HCPA/UFRGS, Porto Alegre, Brazil, ⁴Hospital do Rim, São Paulo, Brazil, ⁵HC-Botucatu/UNESP, Botucatu, Brazil, ⁶Santa Casa de Porto Alegre, Porto Alegre, Brazil, ⁷HC/FMUSP, São Paulo, Brazil, ⁸H. Geral de Fortaleza, Fortaleza, Brazil, ⁹HUWC/UFC, Fortaleza, Brazil, ¹⁰H. Universitário São José, Belo Horizonte, Brazil, ¹¹H. Felício Rocho, Belo Horizonte, Brazil, ¹²Santa Casa de Juiz de Fora, Juiz de Fora, Brazil, ¹³Santa Casa de Montes Claros, Montes Claros, Brazil, ¹⁴Real Hospital Português, Recife, Brazil, ¹⁵H. Universitário Cajuru, Curitiba, Brazil, ¹⁶H. São Francisco na Providencia de Deus, Rio de Janeiro, Brazil, ¹⁷H. Santa Isabel, Blumenau, Brazil, ¹⁸H. Municipal São José, Joinville, Brazil, ¹⁹H. Israelita Albert Einstein, São Paulo, Brazil, ²⁰ABTO, São Paulo, Brazil
*Purpose: Unicenter Brazilian studies reported high incidences (50-70%) of delayed graft function (DGF). This is a multicenter Brazilian study aimed to evaluate the incidence, the…
2020 American Transplant Congress
Public Education about Vascular Composite Allotransplantation and Donation: A Content Analysis of Social Media and Educational Documents
S. Rasmussen¹, M. Henderson¹, N. Anderson², J. Uriarte², B. Doby¹, C. Cooney¹, D. Segev¹, G. Brandacher¹, E. Gordon²
¹Johns Hopkins, Baltimore, MD, ²Northwestern, Chicago, IL
*Purpose: : Consistent and accurate public messaging is crucial in organ donation and transplantation, particularly in the emerging field of vascular composite allotransplantation (VCA). Currently,…
2020 American Transplant Congress
Vascularized Composite Allograft (VCA) Waiting List and Transplant Trends in the U.S
J. Wainright¹, C. Wholley², W. Cherikh¹, D. Klassen³
¹Research, UNOS, Richmond, VA, ²Policy and Community Relations, UNOS, Richmond, VA, ³Chief Medical Officer, UNOS, Richmond, VA
*Purpose: Vascularized Composite Allograft (VCA) transplantation is a rapidly changing field. *Methods: Since the Organ Procurement and Transplantation Network (OPTN) implemented the VCA waiting list…
2020 American Transplant Congress
Efficacy of Photobiomodulation Therapy Combined with Short-Term Immunosuppressants Prolonged Allotransplant Survival in a Rodent Hind-Limb Model
Y. Kuo¹, C. Chen², R. Chen², Y. Li²
¹Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ²Division of Plastic Surgery, Department of Surgery,, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
*Purpose: Photobiomodulation has been applied for accelerating the skeletal muscle repair process. Our formal study demonstrated vitamin D could be involved in allograft survival and…