Abstracts Archive - Page 428 of 1683 - ATC Abstracts

2020 American Transplant Congress
Hepatitis C and Racial Disparity in Liver Transplant Waitlist Additions: Separate Not Equal
C. Wang¹, J. Buggs¹, E. Rogers¹, A. Kumar², N. Kemmer³
¹Transplant Surgery, Tampa General Hospital, Tampa, FL, ²Morsani College of Medicine, University of South Florida, Tampa, FL, ³Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: In 2014, direct-acting antivirals (DAAs) became available as a treatment option for Hepatitis C Virus (HCV) with successful results. Since the implementation of DAAs,…
2020 American Transplant Congress
Creating a Patient Website to Search for Transplant Centers: www.transplantcentersearch.org
C. R. Schaffhausen¹, S. Chu², M. Bruin³, A. Matas⁴, M. Hertz⁵, C. Martin⁵, J. Lake⁶, W. Kim⁷, S. Biggins⁸, J. J. Snyder⁹, B. L. Kasiske⁹, A. K. Israni¹⁰
¹Hennepin Heathcare Research Institute (HHRI), Minneapolis, MN, ²College of Design, University of Minnesota (UMN), Saint Paul, MN, ³College of Design, UMN, Saint Paul, MN, ⁴Department of Surgery, UMN, Minneapolis, MN, ⁵Department of Medicine, UMN, Minneapolis, MN, ⁶Division of Gastroenterology, Hepatology, and Nutrition, UMN, Minneapolis, MN, ⁷Division of Gastroenterology and Hepatology, Stanford University, Stanford, CA, ⁸Division of Hepatology, University of Washington, Seattle, WA, ⁹Scientific Registry of Transplant Recipients, Minneapolis, MN, ¹⁰Department of Medicine, HHRI, UMN, Minneapolis, MN
*Purpose: The Scientific Registry of Transplant Recipients (SRTR) data was used to create a website with a tailored decision guide to help inform patient decisions…
2020 American Transplant Congress
Normothermic Ex Vivo Perfusion of Marginal Liver Grafts Rapidly Stimulates Release of Graft-Derived Exosomes and Markedly Decreases the Inflammatory Pathways Induced at Early Times after Transplant Reperfusion
K. E. Brown¹, K. S. Keslar¹, D. Margeta¹, Q. Liu², A. Simioni², L. Del Angel Diaz², W. M. Baldwin¹, R. L. Fairchild¹, C. Quintini²
¹Lerner Research Institute, Cleveland Clinic, Cleveland, OH, ²Transplant Center, Cleveland Clinic, Cleveland, OH
*Purpose: Normothermic ex vivo machine perfusion of liver grafts (EVLP) is emerging as a superior preservation technology to cold storage. Normothermic EVLP transforms a metabolically…
2020 American Transplant Congress
Patient-Informed Design of an Educational Website on Living Kidney Donation
M. Keller¹, R. Seibert¹, T. Feeley², L. Kayler¹
¹Erie County Medical Center, Buffalo, NY, ²University at Buffalo, SUNY, Buffalo, NY
*Purpose: Web-based education may be a powerful tool to support kidney patients’ learning about living kidney donation (LKD); however, websites that are not user-friendly can…
2020 American Transplant Congress
Kidney Transplant Outcomes in Incarcerated End Stage Renal Disease Patients
R. Rattanavich, T. Hoang, R. Villicana
Transplant institute, Loma Linda University, San Bernadino, CA
*Purpose: Kidney transplantation remains the treatment of choice for end stage renal disease as it improves mortality and morbidity. Outcomes of incarcerated ESRD patients who…
2020 American Transplant Congress
The Pro-Inflammatory Profile of Alcoholic Patients Increases Risk for Ischemia-Reperfusion Injury During Orthotopic Liver Transplantation
A. Q. Terry¹, R. A. Sosa¹, M. Rossetti¹, F. Li¹, J. Nevarez-Mejia¹, B. V. Naini¹, F. M. Kaldas², V. M. Groysberg¹, S. M. Younan², R. W. Busuttil², D. W. Gjertson¹, J. W. Kupiec-Weglinski³, E. F. Reed¹
¹Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA, ²Department of Surgery, UCLA, Los Angeles, CA, ³Departments of Pathology and Laboratory Medicine and Surgery, UCLA, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) elicits cellular damage which triggers a pro-inflammatory immune response that can lower allograft survival in orthotopic liver transplant (OLT) patients. In…
2020 American Transplant Congress
Accomplishment of Ischemia-Free Kidney Transplantation Using Normothermic Machine Perfusion
G. Chen, X. He, C. Wang, X. Yuan, M. Han, Z. Guo
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Ischemia-reperfusion injury (IRI) has been considered an inevitable event in organ transplantation since the first successful kidney transplant was performed in 1954. To avoid…
2020 American Transplant Congress
Bridging the Gap: Normothermic Perfusion of Discarded Livers Significantly Alleviates the Donor Shortage
S. Raigani, R. J. De Vries, C. Carroll, Y. Chen, D. C. Chang, K. Uygun, H. Yeh
Transplant Surgery, Massachusetts General Hospital, Boston, MA
*Purpose: European studies have shown that discarded liver grafts can be successfully transplanted if they meet viability criteria during normothermic machine perfusion (NMP). The potential…
2020 American Transplant Congress
Microbiota Modulates Ischemia-Reperfusion Injury in Mouse Liver Transplantation
S. Kageyama¹, H. Kojima¹, K. Kadono¹, H. Hirao¹, K. J. Dery¹, K. Nakamura², T. Dong³, J. Jacobs³, R. W. Busuttil¹, J. W. Kupiec-Weglinski¹
¹Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA, ²Surgery, Nishi Kobe Medical Center, Kobe, Japan, ³The Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine, Los Angeles, CA
*Purpose: Ischemia-reperfusion injury (IRI) is a major risk factor in orthotopic liver transplantation (OLT). As host microbiota may associate with health or disease, antibiotics (Abx)…
2020 American Transplant Congress
Development of a Split Liver Machine Perfusion Protocol to Provide Comparative Controls in Assessing Therapeutic Interventions
J. A. Attard¹, L. Wallace¹, Y. Boteon¹, V. Ronca¹, D. Osei-Bordom¹, Y. Oo¹, H. Mergental², D. Mirza², S. Afford¹
¹Centre for Liver and Gastroenterology Research, University of Birmingham, Birmingham, United Kingdom, ²Liver Surgery Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom
*Purpose: Ex situ donor liver machine perfusion is developing into a promising tool to test organ viability prior to transplantation and vehicle to assess novel…