Abstracts Archive - Page 416 of 1683 - ATC Abstracts

2020 American Transplant Congress
Frailty at Time of Kidney Transplant Evaluation is Associated with Higher Rate of Waitlist Denial
J. Klein¹, A. Jurgensen², M. Gupta¹, N. Herrera¹, A. Gupta¹, D. Cibrik¹
¹Nephrology, University of Kansas Medical Center, Kansas City, KS, ²University of Kansas Medical Center, Kansas City, KS
*Purpose: To determine the association of patient frailty, as assessed by the Fried frailty score at the time of kidney transplant evaluation (KTE), with kidney…
2020 American Transplant Congress
Risk Factors and Treatment of Recurrent Focal Segmental Glomerulosclerosis after Kidney Transplantation
G. Chen, C. Wang, Z. Wu, X. Liu, Q. Li, L. Chen
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China
*Purpose: Recurrent focal segmental glomerulosclerosis(FSGS) is common after kidney transplantation . We conducted a retrospective cohort study with the aim to investigating the risk factors…
2020 American Transplant Congress
Autophagy Attenuates Renal Allograft Interstitial Fibrosis by Regulating the EndMT Induced by TNF-α
Z. Gui, C. Suo, Z. Wang, S. Fei, Z. Han, J. Tao, H. Chen, L. Sun, X. Ju, R. Tan, M. Gu
Jiangsu Province Hospital, Nanjing, China
*Purpose: Kidney interstitial fibrosis is a significant cause of allograft failure in kidney transplantation. Autophagy is a self-digestive process that eliminates impaired or aged proteins…
2020 American Transplant Congress
An Early Look at the National Liver Review Board
S. Noreen¹, R. Hirose², J. Trotter³, J. Heimbach⁴
¹United Network for Organ Sharing, Richmond, VA, ²University of California - San Francisco, San Francisco, CA, ³Texas Digestive Disease Consultants, Dallas, TX, ⁴Mayo Clinic, Rochester, MN
*Purpose: On May 14, 2019, the National Liver Review Board (NLRB) was implemented, establishing a national structure for liver exceptions comprised of three specialty review…
2020 American Transplant Congress
Unique Podocyte and Multiplex Single-Cell RNASeq Analysis of Paired Sera and Bone Marrow Samples Suggest a Role for Perturbed Hematopoeitic Progenitors in FSGS Recurrence
P. Rashmi, T. Sigdel, A. Alica Da Silva, R. Paul, D. Galligan, J. Wolfe, F. Vincenti, M. Sarwal
University of California San Francisco, San Francisco, CA
*Purpose: Focal Segmental Glomerulosclerosis (FSGS) is the most common cause of nephrotic syndrome, can lead to ESRD, and carries a high burden of recurrence risk…
2020 American Transplant Congress
De Novo Dosing and Trough Attainment Trends of Extended-Release Tacrolimus in the Absence of Dose Adjustments
M. J. Moritz¹, D. R. Stevens², U. Meier-Kriesche², T. A. Horwedel²
¹Department of Surgery, Lehigh Valley Health Network, Allentown, PA, ²Veloxis Pharmaceuticals, Cary, NC
*Purpose: Initial dosing of tacrolimus extended-release tablets (LCPT) was 0.17 mg/kg/day in the pivotal trial in de novo kidney transplant recipients. Dosing subsequent to the…
2020 American Transplant Congress
CMV, EBV and BKV Viremia Rate Varied Depending on the Timing of Conversion to Belatacept (BLT)- from Calcineurin Inhibitor (CNI)-Based Immunosuppression and HLA-Sensitization (HS) Status in Kidney Transplant Patients (KTx Pts)
B. Shin, N. Ammerman, A. Vo, S. C. Jordan, M. Toyoda, S. Sethi
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Viral infections (VI) represent significant morbidity and mortality factors for KTx Pts. We previously showed more VI in BLT-treated Pts compared with CNI Pts…
2020 American Transplant Congress
The Effect of Desensitization Therapy on Sex Disparity in Living Kidney Transplantation
Y. Kakuta¹, M. Okumi¹, T. Kanzawa¹, K. Unagami², H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: Sex- and gender-based disparities which have shown women to have lower access to kidney transplantation have been reported. In living kidney transplantation (LKT), pregnancy-related…
2020 American Transplant Congress
Liver Transplantation with Grafts from Super Obese Donors with a BMI>50
P. Vargas¹, J. M. Cullen¹, P. Northup², J. Oberholzer¹, S. Pelletier¹, N. Goldaracena¹
¹Department of Surgery, Division of Transplantation, University of Virginia Health System, Charlottesville, VA, ²Department of Medicine-Gastroenterology, University of Virginia Health System, Charlottesville, VA
*Purpose: Organ shortage is aggravated by an obesity epidemic. There is limited data on liver transplant (LT) outcomes from liver grafts originating from super obese…
2020 American Transplant Congress
Impact of Concentrations on Conversion from Twice‑Daily to Once‑Daily Tacrolimus in Stable Kidney Graft Recipients: A Single-Center Retrospective Study
Z. Wang, Y. Cao, Y. Fu
Transplant Surgery, Tianjin First Central Hospital, Tian Jin, China
*Purpose: Potential benefits of once-daily tacrolimus include improved adherence to immunosuppressives and decreased Intrapatient variability (IPV) post kidney transplantation. A retrospective analysis was performed to…