Abstracts Archive - Page 411 of 1683 - ATC Abstracts

2020 American Transplant Congress
Quantitative Analysis of Humoral Immunity by Flow-Cytometric Crossmatch Using Molecules of Equivalent Soluble Fluorochromosome (FCXM-MESF)
H. Ishida, M. Furusawa, T. Shimizu, M. Okumi, Y. Kakuta, K. Omoto, K. Tanabe
Tokyo Womens, Tokyo, Japan
*Purpose: In this study, we examined the quantitative significance of humoral immunity by flow-cytometric crossmatch using molecules of equivalent soluble fluorochromosome (FCXM-MESF) in recipients of…
2020 American Transplant Congress
Impact of Rituximab and Apheresis Techniques in Acute Rejection Rates in ABO Incompatible Living Donor Kidney Transplant
I. Revuelta¹, E. De Sousa-Amorim¹, M. Lozano², D. Cucchiari¹, J. Cid², L. Peri³, E. Palou⁴, M. Musquera³, J. Martorell⁵, J. M. Campistol¹, F. Oppenheimer¹, F. Diekmann¹
¹Renal Transplant Unit, Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain, ²Apheresis and Cellular Therapy Unit, Hospital Clinic, Barcelona, Spain, ³Department of Urology, Hospital Clinic, Barcelona, Spain, ⁴Histocompatibility Lab. Department of Immunology, Hospital Clinic, Barcelona, Spain, ⁵Histocompatibility Lab, Department of Immunology, Hospital Clinic, Barcelona, Spain
*Purpose: ABO incompatibility (ABOi) is a widespread option of living kidney donor transplantation (LKDT). However, controversies in rejection, and death-censored graft survival rates are published,…
2020 American Transplant Congress
De Novo Dosing and Trough Attainment Trends of Extended-Release Tacrolimus in the Absence of Dose Adjustments
M. J. Moritz¹, D. R. Stevens², U. Meier-Kriesche², T. A. Horwedel²
¹Department of Surgery, Lehigh Valley Health Network, Allentown, PA, ²Veloxis Pharmaceuticals, Cary, NC
*Purpose: Initial dosing of tacrolimus extended-release tablets (LCPT) was 0.17 mg/kg/day in the pivotal trial in de novo kidney transplant recipients. Dosing subsequent to the…
2020 American Transplant Congress
Conversion to Belatacept (BLT)- from Calcineurin Inhibitor (CNI)-Based Immunosuppression During the First Year Post-Transplant (<1yr Tx) Increases Risk for CMV Infection Through Inhibition of Anti-CMV Humoral Immunity
B. Shin, N. Ammerman, S. Sethi, A. Vo, S. C. Jordan, M. Toyoda
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: We have shown a higer CMV infection rate in kidney Tx patients (KTx Pts) who were converted to BLT 1yr post-Tx. Viral infections are…
2020 American Transplant Congress
CMV, EBV and BKV Viremia Rate Varied Depending on the Timing of Conversion to Belatacept (BLT)- from Calcineurin Inhibitor (CNI)-Based Immunosuppression and HLA-Sensitization (HS) Status in Kidney Transplant Patients (KTx Pts)
B. Shin, N. Ammerman, A. Vo, S. C. Jordan, M. Toyoda, S. Sethi
Cedars-Sinai Medical Center, Los Angeles, CA
*Purpose: Viral infections (VI) represent significant morbidity and mortality factors for KTx Pts. We previously showed more VI in BLT-treated Pts compared with CNI Pts…
2020 American Transplant Congress
Effect of Simultaneous Presence of Anti-Blood Group A/B and -HLA Antibodies on Clinical Outcomes in Kidney Transplantation Across Positive Crossmatch: A Nationwide Cohort Study
H. Kwon, Y. Ko, D. Han
Department of General Surgery, Asan Medical Center, Seoul, Korea, Republic of
*Purpose: ABO-incompatible (ABOi) and positive crossmatch (XM) kidney transplantation (KT) have been considered immunologically challenging. The present study analyzed the clinical outcomes in XM positive…
2020 American Transplant Congress
Hepatologist and Surgeon Experiences Counseling Liver Transplant Candidates for an Organ Offer Decision
C. Schaffhausen¹, M. Bruin², S. Chu³, S. Chinnakotla⁴, J. R. Lake⁵, A. K. Israni⁶
¹Hennepin Heathcare Research Institute (HHRI), Minneapolis, MN, ²College of Design, University of Minnesota (UMN), Minneapolis, MN, ³College of Design, UMN, Minneapolis, MN, ⁴Department of Surgery, UMN, Minneapolis, MN, ⁵Division of Gastroenterology, Hepatology, and Nutrition, UMN, Minneapolis, MN, ⁶Department of Medicine, Hennepin Healthcare, UMN, Minneapolis, MN
*Purpose: Liver transplant candidates receive counseling during evaluations to understand donor risk factors. After long periods on the waitlist, candidates who receive an offer for…
2020 American Transplant Congress
DCD vs DBD Liver Transplantation: Equivalent Charges and Similar Survival- An Effective Expansion of the Donor Pool
N. Singh, K. Helfrich, M. Alebrahim, C. Akateh, K. Mumtaz, A. Logan, A. Schenk, S. Black, E. Elkhammas, K. Washburn, A. El-Hinnawi
Ohio State University, Columbus, OH
*Purpose: The shortage of allografts available for liver transplantation (LT) has prompted the need for expansion of donor pool to include donation after circulatory death…
2020 American Transplant Congress
Minor Negative Effects of Calcineurin Inhibitor Based Immunosuppression on Pregnancy Outcomes after Renal Transplantation in the Netherlands
L. M. Koenjer¹, J. R. Meinderts², A. T. Lely³, M. F. de Jong², O. W. van der Heijden¹, R. G. van der Molen⁴, H. W. van Hamersvelt⁵
¹Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, Netherlands, ²Nephrology, University Medical Center Groningen, Groningen, Netherlands, ³Obstetrics and Gynaecology, University Medical Center Utrecht, Utrecht, Netherlands, ⁴Immunology, Radboud University Medical Centre, Nijmegen, Netherlands, ⁵Nephrology, Radboud University Medical Centre, Nijmegen, Netherlands
*Purpose: Pregnancies after renal transplantation became more frequent over the past years, also in patients with compromised renal function. Immunosuppression may influence pregnancy outcome. It…
2020 American Transplant Congress
The Application of Electron Microscope Examination in Evaluation of Donor Liver Quality in Liver Transplantation
M. Chen¹, X. Lin², Z. Chen¹, M. Han¹, W. Ju¹, X. He¹
¹Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Division of General Surgery, The East Hospital of the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*Purpose: Liver transplantation (LT) is considered as the only curable treatment for patients with end stage liver diseases. Post-operative complications include early allograft dysfunction (EAD),…