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American Transplant Congress abstracts

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  • 2022 American Transplant Congress

    High KDPI Kidneys: Lifelong Freedom from Dialysis for Elderly Patients

    M. M. Romine1, W. Irish2, H. Jones3, A. Aaron2, D. Leeser4

    1Department of Surgery, Eastern Carolina University, Greenville, NC, 2Eastern Carolina University, Greenville, NC, 3Eastern Nephrology Associates, Greenville, NC, 4East Carolina University, Greenville, NC

    *Purpose: According to national data, there is an increase in kidney transplants in patients over 65, corresponding to an overall general increase. Elderly patients continue…
  • 2022 American Transplant Congress

    Low-Dose Aspirin is More Critical Than Statins in Preventing Transplant Renal Artery Stenosis

    B. Ji, X. Tian, G. Jing, T. Yan, X. Wu, G. Cao, C. Zhang

    Urology, Henan Provincial People's Hospital, Zhengzhou, China

    *Purpose: To explore the clinical value of low-dose aspirin (100mg) and statins (10 ~ 20mg) in the prevention of transplant renal artery stenosis (TRAS).*Methods: A…
  • 2022 American Transplant Congress

    Serological Response To Three, Four And Five Doses Of Sars-cov-2 Vaccine In Kidney Transplant Recipients

    S. Ronicke1, B. Osmanodja1, K. Budde1, A. Jens1, C. Hammett1, K. Nadine1, J. Waiser1, B. Zukunft1, F. Bachmann1, M. Choi1, W. Ulrike1, B. Eberspächer2, J. Hofmann2, F. Grunow1, M. Mikhailov1, L. Liefeldt1, K. Eckardt1, F. Halleck1, E. Schrezenmeier1

    1Department of Nephrology and Medical Intensive Care, Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Labor Berlin - Charité Vivantes GmbH, Berlin, Germany

    *Purpose: Mortality from COVID-19 among kidney transplant recipients (KTR) is unacceptably high, and their response to up to three vaccinations against SARS-CoV-2 is strongly impaired.…
  • 2022 American Transplant Congress

    Targeted Delivery of Costimulation Inhibitor to Lymph Nodes Promotes Transplant Tolerance via Fibroblastic Reticular Cells

    J. Zhao1, S. Jung1, X. Li1, H. Zhang1, S. Movahedi1, V. Kasinath1, M. Uehara1, J. Azzi1, P. Sage1, S. Tullius1, J. S. Bromberg2, R. Abdi1

    1Brigham and Women's Hospital, Boston, MA, 2University of Maryland School of Medicine, Baltimore, MD

    *Purpose: The lymph node (LN) is the primary site of alloimmunity activation and regulation during transplantation. Fibroblastic reticular cells (FRCs), the prominent cells of the…
  • 2022 American Transplant Congress

    Early Clinical Experience With Alvr109, A Partially Hla-matched Sars-cov-2 Specific T-cell Therapy, In Immunocompromised Patients With Covid-19

    G. Haidar1, J. Jacobs2, K. Hughes2, K. McCormick2, A. Naqvi2, M. Agha2, T. Bogdanovich2, B. Johnson2, J. Kozar2, E. Lendermon2, C. Marino2, A. Raptis2, F. Silveira2, W. Marshall3, M. Miller3, E. Atillasoy3, J. Mellors2

    1University of Pittsburgh, Pittsburgh, PA, 2UPitt, Pittsburgh, PA, 3Allovir, Waltham, MA

    *Purpose: Therapies for COVID-19 in immunocompromised (IC) patients (pts), including transplant (tx) pts, are limited. We describe our experience with ALVR109, an allogeneic, partially HLA-matched…
  • 2022 American Transplant Congress

    Associated Factors to Physical Inactivity of Kidney Transplant Patients: Subproject of ADHERE Brazil Multicenter Study

    E. S. Sertorio1, F. A. Colugnati1, K. Denhaerynck2, S. De Smet3, J. O. Medina4, M. M. Reboredo5, S. De Geest2, H. Sanders-Pinheiro1, T. ADHERE BRAZIL Study team1

    1Nephrology, Federal University of Juiz de Fora, Juiz de Fora, Brazil, 2Department of Public Health, Institute of Nursing Science, University of Basel, Basel, Switzerland, 3Transplant Research Group, Department of Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium, 4Nephrology, Hsopital do Rim, Federal University of São Paulo, São Paulo, Brazil, 5Pneumology, Federal University of Juiz de Fora, Juiz de Fora, Brazil

    *Purpose: Even though regular physical activity is a current recommendation for kidney transplant recipients (KTR), results from ADHERE Brazil study revealed a high prevalence of…
  • 2022 American Transplant Congress

    Exploring the Differential Access Hypothesis: Do Black Kidney Transplant Candidates Have Less Social Network Access to Potential Living Donors Than White Candidates?

    J. Daw1, M. Roberts1, T. Purnell2

    1Sociology & Criminology, The Pennsylvania State University, University Park, PA, 2Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: This study assesses the ‘differential access’ hypothesis that non-Hispanic Black kidney transplant candidates in the United States have access to fewer healthy, willing potential…
  • 2022 American Transplant Congress

    Organs from Donors with Positive SARS-CoV-2 NAT+ Testing: A Report from the Ad Hoc Disease Transmission Advisory Committee

    L. Danziger-Isakov1, J. D. Goldman1, A. Wooley1, S. Pouch1, A. Agarwal1, G. Berry1, K. Dunn1, S. Ho1, M. Kittleson1, D. H. Lee1, D. Levine1, C. Marboe1, G. Marklin1, R. Razonable1, S. Taimur1, H. Te1, C. Fox2, C. Jett2, S. Booker2, D. Klassen2, R. LaHoz1

    1OPTN, Richmond, VA, 2UNOS, Richmond, VA

    *Purpose: Decision to transplant organs from SARS-CoV-2 NAT+ donors(N+D) balances risk of donor-derived infection with the scarcity of available organs to meet the needs of…
  • 2022 American Transplant Congress

    Comparing The Immunologic Responses Between Kidney Transplant Recipients Receiving Standard Immunosuppression And CNI Reduction After Two Doses Of ChAdOx-1 And A Booster Dose BNT162b2

    S. Phirom1, T. Kitrungphaiboon2, W. Jantarabenjakul2, Y. Avihingsanon2, W. Prasithsirikul3, J. Vanichanan4, P. Hansasuta5, N. Townamchai6

    1Nephrology division, Department of medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 2King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 3Bamrasnaradura infectious disease institute, Bangkok, Thailand, 4Infectious diseases, Department of medicine, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 5Department of Microbiology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 6Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand

    *Purpose: Immunosuppression can impair immunological responses after vaccination in kidney transplant recipients (KTR). However, little is known about the effect of the booster dose of…
  • 2022 American Transplant Congress

    Longevity Matching for Living Donor Renal Transplantation

    S. Karhadkar1, J. Dawes1, K. Wirshup1, J. Kolansky1, A. Gregor1, A. Diamond2, A. DiCarlo1

    1Temple University Hospital, Philadelphia, PA, 2-, Garnet Valley, PA

    *Purpose: Living donor kidney transplantation (LDKT) continues to become a more prevalent treatment method for ESRD and is known to increase both organ availability and…
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