Abstracts Archive - Page 36 of 1683 - ATC Abstracts

2022 American Transplant Congress
A Large-Scale National Cohort Study Assessing the Impact of Diabetes and Obesity on Kidney Transplant Outcomes
V. Rohan¹, M. Casey¹, S. Zemin², P. Baliga², D. Taber²
¹Surgery, Medical University of South Carolina, Charleston, SC, ²Medical University of South Carolina, Charleston, SC
*Purpose: Type 2 Diabetes Mellitus (T2DM) is the most common cause of renal failure in patients undergoing kidney transplantation (KT) and highly correlated with obesity.…
2022 American Transplant Congress
Outcomes of Kidney Transplants in Children: A Single-Center Experience
S. Shaikhouni¹, C. Hanna², I. Sekhon¹, H. Amer¹, M. Prieto³, C. H. Cramer²
¹Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ²Pediatric Nephrology and Hypertension, Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ³Division of Transplantation Surgery, Department of Medicine, Mayo Clinic, Rochester, MN
*Purpose: Over the past decades, immunosuppression regimen protocols, surgical techniques, and outcomes in pediatric kidney transplants (PKT) have evolved. This study describes our center’s experience…
2022 American Transplant Congress
Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft
E. S. Szuter¹, T. Yokose¹, M. T. Guinn¹, J. Ge², I. Rosales³, B. Kwon⁴, P. S. Russell¹, A. Cuenca², D. Kreisel⁵, P. Sage⁶, J. C. Madsen¹, R. B. Colvin³, A. Alessandrini¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, Boston Children's Hospital, Boston, MA, ³Department of Pathology, Massachusetts General Hospital, Boston, MA, ⁴Harvard College, Cambridge, MA, ⁵Department of Surgery, Washington University, St. Louis, MO, ⁶Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA
*Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
2022 American Transplant Congress
Targeted Delivery of Costimulation Inhibitor to Lymph Nodes Promotes Transplant Tolerance via Fibroblastic Reticular Cells
J. Zhao¹, S. Jung¹, X. Li¹, H. Zhang¹, S. Movahedi¹, V. Kasinath¹, M. Uehara¹, J. Azzi¹, P. Sage¹, S. Tullius¹, J. S. Bromberg², R. Abdi¹
¹Brigham and Women's Hospital, Boston, MA, ²University of Maryland School of Medicine, Baltimore, MD
*Purpose: The lymph node (LN) is the primary site of alloimmunity activation and regulation during transplantation. Fibroblastic reticular cells (FRCs), the prominent cells of the…
2022 American Transplant Congress
The Role of HNF4α in Renal Ischemia Reperfusion Injury
A. D. Saha
Toronto General Hospital Research Institute, Toronto, ON, Canada
*Purpose: Ischemia reperfusion injury (IRI) affects all solid organ transplants and impairs renal graft function. However, the mechanisms by which IRI affects grafts are incompletely…
2022 American Transplant Congress
Reflections on the Most Prolific United States Kidney Transplant Surgeon: A Career That Helped Define the Standard of Transplant Care
C. Killian¹, R. Reed², P. MacLennan¹, D. Anderson¹, R. Cannon¹, B. Orandi¹, P. Porrett¹, S. Sheikh¹, C. Young¹, M. J. Hanaway¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Irondale, AL
*Purpose: The standard of care in kidney transplantation has evolved with advances in immunosuppressive therapy. Few transplant surgeons experienced the realization of these advances firsthand.…
2022 American Transplant Congress
Outcomes After Kidney Transplantation in Post Bariatric Surgery Patients: Systematic Review 
N. Pencovici¹, J. Long¹, M. Stegall², A. Kukla¹, T. Diwan¹
¹Mayo Clinic Rochester, Rochester, MN, ²Mayo Clinic, Rochester, MN
*Purpose: Morbid obesity is a barrier to kidney transplantation (KT) due to increased perioperative risks and worse outcomes. Bariatric surgery (BS) is increasingly performed in…
2022 American Transplant Congress
Preoperative Blood Pressure and Risk of Delayed Graft Function in Deceased Donor Kidney Transplantation
S. Wazir, M. Abbas, P. Ratanasreemehta, C. Zhang, C. M. Puttarajappa
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: Evaluate association between preoperative blood pressure and delayed graft function (DGF) in deceased donor kidney transplantation (DDKT)*Methods: In this single center study of adult…
2022 American Transplant Congress
Low-Quality Kidney Allograft Use in Kidney Transplantation is Associated with a Prolonged Post-Transplant Length of Stay
J. A. Kahla¹, C. R. Goff¹, J. A. Goss², A. A. Rana²
¹Department of Student Affairs, Baylor College of Medicine, Houston, TX, ²Division of Abdominal Transplantation, Michael E DeBakey Department of General Surgery, Baylor College of Medicine, Houston, TX
*Purpose: The purpose of this study is to determine the effect of low-quality kidney allografts on recipient hospital length of stay following transplant using five…
2022 American Transplant Congress
Barriers and Facilitators to Care for Patients with Failed Kidney Transplants
A. Huml¹, K. Berg², A. Perzynski², C. Sullivan², A. Sehgal²
¹Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, ²Population Health Research Institute, The MetroHealth System, Cleveland, OH
*Purpose: To understand the barriers and facilitators to care for patients with failed kidney transplants from the perspective of providers.*Methods: Qualitative study employed focus groups…