ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Molecular Diagnosis of Rejection in Liver Transplant Biopsies: The INTERLIVER Study

    K. S. Madill-Thomsen1, P. F. Halloran2, .. The INTERLIVER Study Group3

    1Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, 2University of Alberta, Edmonton, AB, Canada, 3., ., AB, Canada

    *Purpose: Diagnosing rejection in liver transplant biopsies is challenging given the limitations of histology e.g. low kappa values among pathologists. A Molecular Microscope® Diagnostic system…
  • 2020 American Transplant Congress

    Treprostinil is Safe and Potentially Useful in Preventing Ischemia and Reperfusion Injury in Adult Orthotopic Liver Transplant Recipients

    R. Venkataramanan1, I. H. Shaik2, V. C. Pillai3, O. A. Almazroo4, M. K. Miah5, R. Xu2, S. Dharmayan2, A. Al-Khafaji2, S. Ganesh2, M. Molinari2, A. Tevar2, C. Hughes2, A. Humar2

    1School Of Pharmacy, University of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3US Food and Drug Administration,, Silver Spring, MD, 4Saudi FDA, Riyadh, Saudi Arabia, 5Astra Zeneca, Boston, MA

    *Purpose: Ischemia and reperfusion injury (IRI) is one of the unavoidable complications in orthotopic liver transplantion. Hepatic ischemic injury begins during the preservation of the…
  • 2020 American Transplant Congress

    Stanford Integrated Psychosocial Assessment for Transplant Predicts Immunosuppression Non-Adherence after Liver Transplantation

    S. Deutsch-Link1, E. Weinberg2, M. McDougal3, L. Jones4, T. Bitterman2, M. Serper2

    1Medicine, University of Pennsylvania, Philadelphia, PA, 2Gastroenterology & Hepatology, University of Pennsylvania, Philadelphia, PA, 3Drexel University, Philadelphia, PA, 4PCOM, Philadelphia, PA

    *Purpose: Patients with end-stage liver disease presenting for liver transplant (LT) evaluation have a high burden of psychosocial comorbidities. The Stanford Integrated Psychosocial Assessment for…
  • 2020 American Transplant Congress

    Efficacy & Safety of Once Daily Tacrolimus Compared to Twice Daily Tacrolimus after Liver Transplantation

    K. Bzeizi, A. Albenmousa, M. Shawkat, W. Alhamoudi, S. Alabad, R. Troisi, D. Broering

    KFSHRC, Riyadh, Saudi Arabia

    *Purpose: To compare the efficacy and safety of once daily prolonged release tacrolimus compared to twice daily tacrolimus in liver transplantation patients*Methods: Medline, EMBASE, CENTRAL…
  • 2020 American Transplant Congress

    Impact of Donor Race on Tacrolimus Dose Requirement for Liver Transplant Recipients

    N. Nesselhauf1, S. January1, J. Hagopian1, K. Progar1, A. Khan2

    1Pharmacy, Barnes-Jewish Hospital, St. Louis, MO, 2Surgery, Washington University School of Medicine, St. Louis, MO

    *Purpose: It is well described that there is interpatient variability in tacrolimus dose requirements among transplant recipients. CYP3A5 plays a role in this variability. Black…
  • 2020 American Transplant Congress

    Hepaticojejunostomy versus Duct to Duct Anastomosis in Liver Transplantation: An Old Question Revisited

    A. M. Elsabbagh, M. T. Shamaa, A. Al-Kurd, F. Tinney, T. Ivanics, A. Mohamed, K. Delvecchio, S. Yeddula, M. Rizzari, K. Collins, A. Yoshida, M. Abouljoud, S. Nagai

    Henry Ford Hospital, Detroit, MI

    *Purpose: Two surgical techniques are currently used for biliary reconstruction and each has its advantages/disadvantages. However, it is unclear if the used technique can impact…
  • 2020 American Transplant Congress

    Shorter Waiting Time Was Associated with Higher Risk of Recurrence of Hepatocellular Carcinoma in Liver Transplantation

    T. Kitajima1, S. Nagai1, D. Moonka2, S. Yeddula1, O. Rizzo1, M. Kavousi1, R. Salgia2, M. Rizzari1, K. Collins1, A. Yoshida1, M. S. Abouljoud1

    1Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI, 2Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI

    *Purpose: Liver transplantation (LT) is an established treatment option for hepatocellular carcinoma (HCC). After 6-month waiting rule was implemented, the impact of wait-listing (WL) time…
  • 2020 American Transplant Congress

    Liver Transplantation for Primary Liver Sarcoma in Children-The US Experience from the Scientific Registry for Transplant Recipients (1988-2018)

    A. Amin, K. Soltys, S. Ranganathan, G. Bond, A. Khanna, A. Ganoza, Q. Sun, G. Mazariegos, R. Sindhi

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: Primary liver sarcomas (PLS) are rare tumors and encompass subtypes with diverse histology and varying outcomes. These subtypes include embryonal sarcoma (ES), rhabdomyosarcoma (RMS),…
  • 2020 American Transplant Congress

    Bad Actors within Milan Criteria Undergoing OLT- Characterizing Their Pre-Transplant Tumor Behavior and Response to Locoregional Therapy

    A. Mathur, E. Baughan, A. Griesemer, M. Najjar, O. Perez, A. Qian, T. Kato, J. Emond

    Columbia University, New York, NY

    *Purpose: Orthotopic Liver Transplantation (OLT) remains a curative option for hepatocellular carcinoma (HCC). Disparity between the supply and demand for OLT necessitates the transplant of…
  • 2020 American Transplant Congress

    Early Recurrence Of Hepatocellular Carcinoma Following Transplantation: Risk Score From A Multi-institutional Study Of > 3000 Patients

    P. Tabrizian1, M. Holzner2, V. Agopian3, R. Busuttil3, G. Sapisochin4, N. Mehta5, F. Yao5, J. Roberts6, S. Florman1, M. E. Schwartz1, T. Ivanics7, J. Emond8, B. Samstein9, R. Brown, MD, MPH9, M. Najjar10, W. Chapman11, M. Doyle11, K. Halazun9

    1Transplant, Mount Sinai Medical Center, New York, NY, 2Surgery, Georgetown University Hospital, Washington DC, MD, 3Transplant, David Geffen School of Medicine at UCLA, Los Angeles, CA, 4Transplant, Univeristy of Toronto, Toronto, ON, Canada, 5Transplant, UCSF, San Francisco, CA, 6Transplantation, UCSF, San Francisco, CA, 7Transplant, University of Toronto, Toronto, ON, Canada, 8Transplant, Columbia University Medical Center, New York, NY, 9Transplant, Weill Cornell Medical Center, New York, NY, 10Transplant, Columbia Medical Center, New York, NY, 11Transplant, Washington University School of Medicine, St Louis, MO

    *Purpose: Early recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) carries a poor prognosis. We aimed to develop a risk score for early HCC…
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