Abstracts Archive - Page 352 of 1683 - ATC Abstracts

2020 American Transplant Congress
Mesenchymal Stromal Cell Treatment of Kidneys During Normothermic Machine Perfusion is Safe and Feasible with Effective Traceability after Transplantation
K. Rozenberg¹, S. Lohmann², M. Pool³, M. Eijken⁴, U. Møldrup⁵, B. Møller⁶, J. Sierra-Parraga⁷, M. Hoogduijn⁷, L. Lo Faro¹, C. Moers³, J. Hunter¹, A. Keller², H. Leuvenink³, C. Baan⁷, R. Ploeg¹, B. Jespersen²
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ²Department of Clinical Medicine, Aarhus University, Aarhus, Denmark, ³Department of Surgery, University Medical Center Groningen, Groningen, Netherlands, ⁴Department of Renal Medicine, Aarhus University, Aarhus, Denmark, ⁵Department of Urology, Aarhus University, Aarhus, Denmark, ⁶Department of Clinical Immunology, Aarhus University, Aarhus, Denmark, ⁷Department of Internal Medicine, Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands
*Purpose: Marginal kidneys are increasingly being accepted to decrease waiting time for a transplant. Normothermic machine perfusion (NMP) is a technique that allows delivery of…
2020 American Transplant Congress
Mir-124/ire-1α Affects Renal Ischemia/Reperfusion Injury by Regulating Endoplasmic Reticulum Stress in Renal Tubularepithelial Cells
C. Ding, W. Xue
Department of Renal Transplantation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China
*Purpose: In this study, we investigated the protective functions of miR-124 on renal I/R injury both in vivo and in vitro and explored its underlying…
2020 American Transplant Congress
Anti-CD321 Antibody (90G4) Protects Liver against Ischemia Reperfusion Injury in a Murine Model
E. Yin¹, T. Fukuhara², H. Bashuda¹, K. Uchida³
¹Atopy Research Center, Juntendo University School of Medicine, Tokyo, Japan, ²Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan, ³Juntendo Advanced Research Institute for Health Science, Juntendo University School of Medicine, Tokyo, Japan
*Purpose: Ischemia reperfusion results in increased transmigration of leukocytes into tissue. This eventually leads to post transplant graft damage after organ transplantation. CD321 (also known…
2020 American Transplant Congress
Supporting “The Decision Project:” Understanding Perceptions of Organ, Eye, and Tissue Donation among Baltimore City Community Members
M. Johnson¹, A. Saha¹, M. Waldram¹, I. Johnson², L. Price², A. Coleman², C. Alexander², D. Segev¹, M. Henderson¹
¹Johns Hopkins, Baltimore, MD, ²The Living Legacy Foundation of Maryland, Halethorpe, MD
*Purpose: Using information provided by the Maryland Motor Vehicle Administration (MVA), it was found that the zip code 21205 in Baltimore City had one of…
2020 American Transplant Congress
The Role of Complement-Split Products as Biomarkers for Acute Antibody-Mediated Rejection of Kidney Allografts
B. G. Abu Jawdeh¹, B. Campos-Naciff¹, K. Harrison¹, K. Meganathan¹, A. Kumar², M. Anand¹, A. Govil¹, E. S. Woodle¹, B. P. Dixon³
¹University of Cincinnati, Cincinnati, OH, ²All India Institute of Medical Sciences, New Delhi, India, ³University of Colorado, Aurora, CO
*Purpose: Acute antibody-mediated rejection (AMR) is mediated by the activation of the classical complement system in addition to non-complement dependent inflammatory pathways. Complement fixation by…
2020 American Transplant Congress
Monitoring the Removal of Donation Service Area from Lung Allocation
R. R. Goff¹, R. Daly², E. D. Lease³
¹Research, United Network for Organ Sharing, Richmond, VA, ²Mayo Clinic, Rochester, MN, ³University of Washington, Seattle, WA
*Purpose: In 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor service area (DSA) with a 250…
2020 American Transplant Congress
Metabolism Reprogramming During Conventional versus Ischemia-Free Liver Transplantation
Z. Guo¹, Z. Zhang¹, N. Gao¹, H. Zhang², X. He¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, ²Sun Yat-sen University, Guangzhou, China
*Purpose: Our group has developed a novel transplant procedure called ischemia-free liver transplantation (IFLT), during which the liver can be procured, preserved and implanted without…
2020 American Transplant Congress
Long Term Liver Transplant Survivors
M. Haberal¹, E. Ayvazoglu Soy¹, G. Moray¹, F. Ozcay², A. Torgay³
¹Department of General Surgery, Division of Transplantation, Baskent University, Ankara, Turkey, ²Pediatric Nephrology, Baskent University, Ankara, Turkey, ³Anaesthesia, Baskent University, Ankara, Turkey
*Purpose: Few reports mentioned about long term survey. In this study, we aimed to report the outcomes of our long term LT survivors (LTS).*Methods: Our…
2020 American Transplant Congress
A Large Animal Model of Ex-Vivo Lung Perfusion as a Platform to Deliver Therapeutic Agents to Lungs Before Lung Transplant
T. M. Egan¹, B. Haithcock¹, M. H. Ali¹, J. W. Blackwell¹, B. Masuodi¹, S. Shipley², T. Long³, A. Akerman¹, S. Montgomery⁴, H. Yuan⁵, P. Stewart⁶, J. Potenziano⁷, C. Sekaran⁷, R. Fitch⁷
¹Surgery, UNC at Chapel Hill, Chapel Hill, NC, ²Department of Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, ³Pathology and Laboratory Medicine,, UNC at Chapel Hill, Chapel Hill, NC, ⁴Pathology and Laboratory Medicine, UNC at Chapel Hill, Chapel Hill, NC, ⁵Radiology, UNC at Chapel Hill, Chapel Hill, NC, ⁶Gillings Global School of Public Health, UNC at Chapel Hill, Chapel Hill, NC, ⁷Mallinckrodt Pharmaceuticals, Hazelwood, MO
*Purpose: Ex-vivo lung perfusion (EVLP) has been used to evaluate lung function before lung transplant (LT). We used EVLP to expose lungs recovered 6 hours…
2020 American Transplant Congress
Assessment of HEALTh LIteracy on MEdication ADheREnce and Graft Outcomes in KIdney Transplant Recipients (Hallmark)
M. Leung¹, A. Dhanda², S. Kwan³, A. Zienkiewicz³, E. Waters³, N. Wood³, L. Young³, C. Bannon³
¹Pharmacy, St. Paul's Hospital, Vancouver, BC, Canada, ²Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ³Nephrology, St. Paul's Hospital, Vancouver, BC, Canada
*Purpose: Upon successful kidney transplantation, many patients have difficulty adhering to their new immunosuppression medication regimens. Previous studies have established low health literacy to be…