Abstracts Archive - Page 318 of 1683 - ATC Abstracts

2021 American Transplant Congress
Evaluation of Safety and Efficacy of PCSK9 Inhibitors in Solid Organ Transplant Recipients: Experience at a Large Multi-organ Transplant Center
A. Ucci¹, M. Norris², J. Trofe-Clark², T. Fallah², M. Meck¹, R. Samudralwar¹, M. V. Genuardi³
¹Hospital of Univ of Pennsylvania, Philadelphia, PA, ²Penn Transplant Institute, Hospital of Univ of Pennsylvania, Philadelphia, PA, ³Cardiovascular Medicine Div, Hospital of Univ of Pennsylvania, Philadelphia, PA
*Purpose: The aim of the study was to characterize the efficacy and safety of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors in solid organ transplant…
2021 American Transplant Congress
Review of Outcomes After Diagnosis of Malignancy in Kidney Transplant Patients: Unos Database
H. Patel¹, N. Agrawal¹, R. Gupta¹, P. Geetha², A. Abdul Razzack³, F. Cardarelli¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ³Medicine, Dr. NTR University of Health Sciences, Vijaywada, India
*Purpose: Malignancy is the third major cause of death among transplant recipients. Among the transplant recipients, Patient and kidney transplant outcomes after the diagnosis of…
2021 American Transplant Congress
SARS-CoV-2 Antibody Response After Induction Therapy in Kidney Transplant Recipients
M. Lubetzky¹, S. Sultan², Z. Zhao³, M. Cushing³, Z. Kapur¹, S. Albakry¹, N. Hauser¹, J. Marku-Podvorica¹, R. Craig-Schapiro², J. Lee¹, T. Salinas¹, M. Aull², S. Kapur², M. Suthanthiran¹, D. Dadhania¹
¹Nephrology, Weill Cornell-NYPresbyterian, New York, NY, ²Transplant Surgery, Weill Cornell-NYPresbyterian, New York, NY, ³Pathology, Weill Cornell-NYPresbyterian, New York, NY
*Purpose: SARS-CoV-2 antibody prevalence in kidney transplant recipients is beginning to be reported, although little is known about the humoral immune response in the immediate…
2021 American Transplant Congress
Outcomes of Downstaging Hepatocellular Carcinoma (HCC) to within Milan Criteria Before Liver Transplantation (LT): A Multicenter Analysis of the “All-comers” Protocol
B. Natarajan¹, P. Tabrizian², M. Hoteit³, C. Frenette⁴, T. Ghaziani⁵, R. Dhanasekaran⁵, N. Parikh⁶, J. Guy⁷, A. Shui¹, S. Florman², F. Yao¹, N. Mehta¹
¹UCSF, SF, CA, ²Mt Sinai, NY, NY, ³U Penn, Philadelphia, PA, ⁴Scripps, La Jolla, CA, ⁵Stanford, Palo Alto, CA, ⁶U Michigan, Ann Arbor, MI, ⁷CPMC, SF, CA
*Purpose: Patients with HCC meeting UNOS-downstaging (DS) criteria (1 lesion 5.1-8 cm, 2-3 lesions at least one 3.1-5 cm and total tumor diameter (TTD) ≤8…
2021 American Transplant Congress
Delayed Graft Function in Pediatric Living Donor Kidney Transplantation
M. MacConmara, J. Shah, L. de Gregorio, D. Desai, P. Vagefi, C. S. Hwang
Surgery, UT Southwestern Medical Center, Dallas, TX
*Purpose: Pediatric recipients of living donor kidneys have a low rate of delayed graft function (DGF). The aim of this study was to examine the…
2021 American Transplant Congress
A Molecular Classifier Identifies Antibody-Mediated Rejection-Associated Changes in Lung Transplant Biopsies
K. S. Madill-Thomsen¹, K. M. Halloran², M. Parkes¹, P. F. Halloran¹, &. the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Identifying lung transplant antibody-mediated rejection (ABMR) has been controversial. We compared gene expression in donor-specific antibody (DSA) positive vs. DSA negative lung transbronchial biopsies…
2021 American Transplant Congress
Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases: A Multicenter Experience
L. I. Ruffolo¹, K. Sasaki², K. Tomiyama¹, A. Nair¹, M. Orloff¹, B. Al-Judaibi³, M. Levstik³, M. Laryea³, K. Dokus¹, J. Errigo¹, A. Moro², C. Quintini², K. Hashimoto², M. Fujiki², K. Menon², C. Kwon², T. Diago Uso², R. Hernandez-Alejandro¹, F. Aucejo²
¹Surgery, University of Rochester Medical Center, Rochester, NY, ²Surgery, The Cleveland Clinic Foundation, Cleveland, OH, ³Transplant Hepatology, University of Rochester Medical Center, Rochester, NY
*Purpose: Colorectal cancer is the third leading cause of cancer related death, unfortunately 50% of patients will develop colorectal liver metastases (CRLM), and a minority…
2021 American Transplant Congress
Long Term Safety and Efficacy of Tocilizumab (anti-il6r, Tcz) Therapy in the Treatment of Refractory Chronic Antibody Mediated Rejection (cabmr) in 25 Pediatric Renal Transplant Recipients
M. Pearl¹, P. Weng¹, A. Dokras², H. Pizzo³, J. Garrison³, C. Butler¹, J. Q. Zhang¹, K. Lim³, E. Reed¹, I. Kim³, M. Haas³, X. Zhang³, R. Ettenger¹, S. Jordan³, D. Puliyanda³
¹Pediatric Nephrology, UCLA Medical Center, Los Angeles, CA, ²Pediatric Nephrology, UT South Western, Dallas, CA, ³Pediatric Nephrology, Cedars Sinai Medical Center, West Hollywood, CA
*Purpose: Development of de novo donor specific antibodies (DSA) post renal transplantation puts pediatric patients at risk for chronic Antibody Mediated Rejection (cABMR) and allograft…
2021 American Transplant Congress
Assessing the Accuracy of the Lung Allocation Score
N. Dussault¹, W. Parker¹, R. Jablonski¹, E. Garrity¹, M. Churpek²
¹University of Chicago, Chicago, IL, ²University of Wisconsin-Madison, Madison, WI
*Purpose: The Lung Allocation Score (LAS) relies on the performance of two cox proportional hazards models that estimate waitlist and post-transplant survival. These models were…
2021 American Transplant Congress
Role of Baseline PD-1 Checkpoint Inhibitor Pathway Expression in Bridge to Liver Transplant Hepatocellular Carcinoma
K. Nunez, T. Sandow, M. Hibino, A. Cohen, P. Thevenot
Ochsner Health, New Orleans, LA
*Purpose: Response to first line liver-directed therapy (LDT) in hepatocellular carcinoma (HCC) has important implications in both bridge to transplant (BTT) success as well as…