Abstracts Archive - Page 303 of 1683 - ATC Abstracts

2021 American Transplant Congress
CD40 Blockade by the Fc-Silent Immunosuppressive Antibody Iscalimab Results in Diminished B Cell Activation and Differentiation and is Paralleled by Whole Blood Gene Expression Data
R. Kraaijeveld¹, M. W. van den Hoogen¹, A. E. de Weerd¹, E. Ferroro², G. Robert², U. Laessing², B. Haraldsson², J. S. Rush², C. C. Baan¹
¹Erasmus MC, Rotterdam, Netherlands, ²Novartis Pharmaceuticals AG, Basel, Switzerland
*Purpose: Blockade of costimulatory molecule CD40 by the Fc-silent immunosuppressive drug Iscalimab has shown to inhibit acute alloreactivity in non-human primates and is currently being…
2021 American Transplant Congress
Pediatric Donation During COVID-19 Pandemic
M. MacConmara, B. Wang, L. de Gregorio, J. Shah, D. Desai, S. Hanish, P. Vagefi, C. S. Hwang
Surgery, UT Southwestern Medical Center, Dallas, TX
*Purpose: The COVID-19 pandemic led to a decrease in transplantation throughout the United States. We examined the impact of the pandemic in regards to the…
2021 American Transplant Congress
The Pediatric National Liver Review Board: What Happens to Waitlist Registrations with Denied Exception Forms?
J. Foutz¹, C. Martinez¹, A. Henderson¹, E. K. Hsu², E. R. Perito³, J. Heimbach⁴
¹United Network for Organ Sharing, Richmond, VA, ²Seattle Children's Hospital, Seattle, WA, ³UCSF, San Francisco, CA, ⁴Mayo Clinic, Rochester, MN
*Purpose: On 5/14/19, the exceptions review process for pediatric liver transplant (LT) candidates was changed from 11 Regional Review Boards to one National Pediatric Liver…
2021 American Transplant Congress
Degree of T Cell Infiltration Predicts Treatment Response in Pediatric Liver Late Acute Cellular Rejection
M. Rogers, G. Begum, Q. Sun, A. Peters
Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Late acute cellular rejection (ACR) occurs >6mo post-liver transplant and is associated with chronic rejection and allograft loss. Currently, no diagnostic features predict ACR…
2021 American Transplant Congress
The Confluence of Race, Socioeconomic Deprivation, and Waitlist Mortality for Children Awaiting Liver Transplant
S. Wadhwani¹, J. Ge¹, L. Gottlieb¹, C. Lyles¹, A. F. Beck², J. Bucuvalas³, U. Kotagal², J. C. Lai¹
¹University of California San Francisco, San Francisco, CA, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: Social determinants like racism, ethnocentrism, and neighborhood socioeconomic deprivation are associated with poor outcomes for children after liver transplant. We studied the relationship between…
2021 American Transplant Congress
Impact of a Latinx Kidney Transplant Clinic
P. Serrano Rodriguez
Abdominal Transplant Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC
*Purpose: To evaluate the impact of a Latinx clinic in our institution. With a growing increase of end stage renal disease (ESRD)in the Latino population…
2021 American Transplant Congress
Initial Kidney Transplant Evaluations with Telehealth: Is it a Pandemic Only Practice?
A. Govil¹, E. Tims², C. Siemer², J. Harris², C. King², S. Shah¹, C. Thakar¹
¹Univ of Cincinnati, Cincinnati, OH, ²UC Health, Cincinnati, OH
*Purpose: COVID -19 pandemic presented an unprecedented challenge to health care systems. It disrupted the transplant processes including evaluations, especially in rural or other geographically…
2021 American Transplant Congress
Characterization of Retransplantation Following Graft Failure Due to Bkvn
K. Nguyen¹, H. Curtis², J. Panichella², H. Resweber³, A. Di Carlo², S. Karhadkar¹
¹Surgery, Temple University School of Medicine, Philadelphia, PA, ²Surgery, Temple University School of Medicine, Philadephia, PA, ³Surgery, Temple University School of Medicine, Gladwyne, PA
*Purpose: Immunosuppression following kidney transplantation allows for the reactivation of BK polyomavirus (BKV)- frequently implicated in graft dysfunction and failure. Although BKV Nephropathy (BKVN) was…
2021 American Transplant Congress
Growth Differentiation Factor 15 Predictor Value is Superior to Troponin I in the Evaluation of Kidney Transplant Candidates
M. de Cos Gomez¹, M. Garcia Unzueta², A. Benito Hernandez¹, J. Mazon Ruiz¹, M. Perez Arnedo¹, A. Aguilera Fernandez¹, R. Valero San Cecilio¹, J. Ruiz San Millan¹, E. Rodrigo Calabia¹
¹Nephrology, Marques de Valdecilla University Hospital - IDIVAL, Santander, Spain, ²Clinical Analysis, Marques de Valdecilla University Hospital - IDIVAL, Santander, Spain
*Purpose: Pretransplant cardiac troponin I (cTNI) has demonstrated its predictor value of survival after kidney transplant in previous studies. Growth differentiation factor 15 (GDF-15) is…
2021 American Transplant Congress
Response to a Pandemic: The Fall and Rise of Kidney Transplantation in the US
S. Bisen¹, B. Boyarsky¹, W. Werbel¹, J. Snyder², J. Garonzik-Wang¹, D. Segev¹, A. Massie¹
¹JHU, Baltimore, MD, ²SRTR, Minneapolis, MN
*Purpose: During the first wave of the COVID-19 epidemic in March-April 2020, waitlist registrations and living/deceased donor kidney transplants (LDKT/DDKT) dropped substantially. A second wave…