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American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Evaluating Pneumocystis Jiroveci Pneumonia Prophylaxis in Lung Transplant Recipients

    J. Sharkey, K. McMurry, J. Park, C. Carlson, K. Gregg, D. Kaul, D. Lyu, L. Fitzgerald

    Michigan Medicine, Ann Arbor, MI

    *Purpose: The incidence of Pneumocystis jiroveci pneumonia (PJP) in lung transplant recipients (LTRs) on PJP prophylaxis is not well documented yet reported as high as…
  • 2021 American Transplant Congress

    Epidemiology and Risk Factors for Invasive Fungal Infection in Pancreas Transplant in the Absence of Fungal Prophylaxis

    J. Burkey1, J. M. Chen2, A. A. Sharfuddin2, M. S. Yaqub2, A. J. Lutz2, J. A. Powelson2, J. A. Fridell2, N. Barros2

    1Butler University College of Pharmacy and Health Sciences, Indianapolis, IN, 2Indiana University Health, Indianapolis, IN

    *Purpose: Invasive fungal infections (IFI) remain a rare yet dreaded complication following pancreas transplantation. Current guidelines recommend antifungal prophylaxis in patients with 1 or more…
  • 2021 American Transplant Congress

    Molecular Epidemiology of Extended-Spectrum Cephalosporin-Resistant Enterobacterales Bloodstream Infections Among Solid Organ Transplant Recipients

    J. A. Anesi1, E. Lautenbach1, P. D. Tamma2, K. A. Thom3, K. Alby4, E. A. Blumberg1, W. Bilker1, J. Omorogbe1, P. Tolomeo1, A. Werzen3, J. Han5

    1University of Pennsylvania, Philadelphia, PA, 2Johns Hopkins University, Baltimore, MD, 3University of Maryland, Baltimore, MD, 4University of North Carolina, Chapel Hill, NC, 5GlaxoSmithKline, Rockville, MD

    *Purpose: Solid organ transplant recipients (SOTR) have been significantly impacted by the emergence of multidrug-resistant bacteria, including extended-spectrum cephalosporin-resistant (ESC-R) Enterobacterales (EB). We determined the…
  • 2021 American Transplant Congress

    Impact of a Pharmacist-driven Immunization Clinic on Vaccination Rates in Pre-liver Transplant Patients

    A. Poparad-Stezar1, B. Summers1, M. Fitzmaurice1, K. Hakamiun2, N. Sulejmani3, A. Jantz1

    1Henry Ford Hospital, Detroit, MI, 2Select Medical, Wyandotte, MI, 3CareDx, Inc., Sterling Heights, MI

    *Purpose: Infectious diseases are a leading cause of morbidity and mortality among patients with end-stage liver disease (ESLD). Vaccination data of ESLD patients pre- and…
  • 2021 American Transplant Congress

    The Effect of the Different Donor-Derived HLA T-Cell Epitope Targets on the Development of T Cell-Mediated Rejection After Kidney Transplantation

    A. Senev, E. Van Loon, M. Emonds, M. Naesens

    Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium

    *Purpose: Many kidney allografts fail due to rejections caused by the donor and recipient HLA incompatibility. Recent studies have shown that HLA-DR and DQ mismatches…
  • 2021 American Transplant Congress

    Impact of a Cmv Cell Mediated Immunity Based Protocol on Guiding Cmv Prophylaxis Following Pediatric Liver Transplantation – A Single Center Experience

    G. Kalkan1, S. Ball2, L. McConnell2, D. M. Desai3, A. Aqul3, P. K. Sue1

    1Infectious Disease, University of Texas Southwestern Medical Center, Dallas, TX, 2Solid Organ Transplant Program, Children's Health, Dallas, TX, 3Solid Organ Transplant Program, University of Texas Southwestern Medical Center, Dallas, TX

    *Purpose: Cytomegalovirus (CMV) is an important cause of morbidity following pediatric orthotopic liver transplantation (OLT), especially among high risk (HR) CMV D+/R- recipients. In 2019,…
  • 2021 American Transplant Congress

    Effective Patient Throughput on the Transplant Surgery Service

    E. M. Thomas1, P. K. Shah1, S. Beasley2, A. Saad1, M. Rani1, F. Cigarroa1

    1UT Health San Antonio, San Antonio, TX, 2University Health, San Antonio, TX

    *Purpose: Hospital bed capacity and patient throughput are persistent challenges for medical centers. One established strategy for increasing patient throughput and decompressing Emergency Departments is…
  • 2021 American Transplant Congress

    Use of Granulocyte Colony Stimulating Factor After Lung Transplantation is Not Associated with Increased Likelihood of Acute Cellular Rejection

    S. Fredrick1, C. Iasella2, L. Sacha3, R. Rivosecchi3, M. Morrell3, P. Sanchez3, J. Pilewski3, M. Snyder3, J. McDyer3, C. Moore3

    1University of Rochester Medical Center, Rochester, NY, 2University of Pittsburgh School of Pharmacy, Pittsburgh, PA, 3University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: The cause of neutropenia in lung transplant recipients is multifactorial, including medications, viral infections, and antecedent disease. Granulocyte colony-stimulating factor (G-CSF) is commonly used…
  • 2021 American Transplant Congress

    Development of Diagnosis Method of Acute Graft Rejection After Kidney Transplantation Using Metabolome Analysis by Liquid Biopsy Approach

    H. Iwamoto1, M. Sugimoto2, O. Konno1, I. Akashi3, M. Okihara1, Y. Kihara1, T. Ueno1

    1Kidney Transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan, 2Research and Development Center for Minimally Invasive and Preemptive Medicine, Institute of Medi, Tokyo Medical University, Tokyo, Japan, 3Kidney transplantation Surgery, Tokyo Medical University, Hachioji Medical Center, Tokyo, Japan

    *Purpose: Presently, a definitive diagnosis of organ dysfunction after transplantation (such as acute rejection) is dependent on conventional histopathological evaluation using an invasive biopsy procedure…
  • 2021 American Transplant Congress

    Inflammation in Scarred Cortex (i-IFTA) is Significantly Associated with T Cell-mediated Rejection (TCMR), but Not Antibody-mediated Rejection (ABMR), in Renal Allograft Biopsies (Bx)

    H. Zhang

    Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: I-IFTA in renal allograft Bx has been found to be associated with decreased death-censored graft survival. Moderate to severe i-IFTA (2 or 3) is…
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