ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Impact of Graft Quality on Patient Survival in Sick Patients

    G. Handing1, S. Keeling1, C. Christmann1, N. Galvan2, C. O’Mahony2, J. Goss2, R. Cotton2, A. Rana2

    1School of Medicine, Baylor College of Medicine, Houston, TX, 2Michael E DeBakey Department of Surgery, Division of Abdominal Transplant, Houston, TX

    *Purpose: It is widely accepted in the literature that patients who have a Model for End Stage Liver Disease (MELD) Score greater than 30 incur…
  • 2021 American Transplant Congress

    Pregnancy Outcomes in 39 Lung Transplant Recipients

    S. Constantinescu1, L. A. Coscia2, A. Yusuf2, S. Rao3, M. J. Moritz4

    1Lewis Katz School of Medicine at Temple University, Philadelphia, PA, 2Transplant Pregnancy Registry International, Philadelphia, PA, 3University of Virginia Heath System, Charlottesville, VA, 4Lehigh Valley Health Network, Allentown, PA

    *Purpose: The purpose of this study is to describe 52 pregnancies in 39 lung transplant recipients reporting to the Transplant Pregnancy Registry International (TPRI) from…
  • 2021 American Transplant Congress

    Guiding Therapeutic Plasma Exchange for Amr Treatment in Lung Transplant Recipients Using Serial Dilution in Single Antigen Bead Assay

    O. A. Timofeeva1, J. Choe2, M. Alsammak2, E. J. Yoon2, S. Geier2, K. Carney2, J. Au2, A. Diamond2, J. A. Galli2, K. Shenoy2, A. Mamary2, S. Seghal2, P. Mullhal2, Y. Toyoda2, N. Shigemura2, F. Cordova2, G. Criner2, J. Brown2

    1MedStar Georgetown University Hospital, Washington, DC, 2Temple University Hospital, Philadelphia, PA

    *Purpose: Development of donor‐specific antibodies (DSA) is associated with poor outcomes in lung transplantation. Patients who are presented with at least probable AMR require treatment;…
  • 2021 American Transplant Congress

    Classification of Distinct Patterns of Ischemic Cholangiopathy Following DCD Liver Transplantation: Distinct Clinical Courses and Long-Term Outcomes from a Multicenter Cohort

    K. P. Croome1, A. K. Mathur2, B. Aqel2, L. Yang1, J. K. Heimbach3, T. Taner3, C. B. Rosen3, R. Paz-Fumagalli1, C. Taner1

    1Mayo Clinic Jacksonville, Jacksonville, FL, 2Mayo Clinic Arizona, Scottsdale, AZ, 3Mayo Clinic Rochester, Rochester, MN

    *Purpose: As the number of donation after circulatory death (DCD) liver transplants (LTs) performed in the United States continues to increase annually, there has been…
  • 2021 American Transplant Congress

    Oxalate Nephropathy After Kidney Transplant: Defining Histological Patterns, Contributing Factors and Graft Outcome

    N. Jakob1, A. Chuu1, J. Ninan1, E. Lim1, N. Zhang1, H. Amer2, F. Cosio2, H. Wadei3, M. Ryan1, C. Cortese3, L. Cornell2, M. Keddis1

    1Nephrology, Mayo Clinic, Scottsdale, AZ, 2Nephrology, Mayo Clinic, Rochester, MN, 3Nephrology, Mayo Clinic, Jacksonville, FL

    *Purpose: The objective of this study is to evaluate KTx recipients with biopsy proven oxalate nephropathy (ON) to better define risk factors, histologic patterns and…
  • 2021 American Transplant Congress

    Optimal Antimicrobial Duration for Donor Positive Cultures in Kidney Transplant Recipients

    J. Ferrante, K. Schnelle, M. Palettas, S. Sarwar, H. Winters, M. Chunduru

    Pharmacy, The Ohio State University Wexner Medical Center, Columbus, OH

    *Purpose: Utilization of organs from infected donors carries the risk of transmission of the donor organism to the recipient. While antimicrobials are recommended in recipients…
  • 2021 American Transplant Congress

    Cyp3a5 Extensive Metabolizer Phenotype May be Associated with an Increase in Class 2 Donor Specific Antibodies and Antibody-Mediated Rejection

    S. Mirza1, N. Wilson2, J. Van Zyl2, P. Nguyen2, T. Sam2, S. Hall2, M. Askar2, R. Patel2

    1Texas Tech Univeristy Health Sciences Center Jerry H. Hodge School of Pharmacy, Dallas, TX, 2Baylor University Medical Center at Dallas, Dallas, TX

    *Purpose: Tacrolimus (TAC) metabolism is highly dependent on CYP3A5, yet there is limited data on the effect of CYP3A5 genetic polymorphisms in heart transplant recipients…
  • 2021 American Transplant Congress

    Outcomes of IVIG Monotherapy for Donor-Specific Antibodies After Lung Transplantation

    K. Spence, S. Heeney, M. Morrison, S. A. Rega, F. D. Irene, K. B. Harrison, C. M. Shaver

    Vanderbilt University Medical Center, Nashville, TN

    *Purpose: De novo donor-specific antibodies (DSA) are a risk factor for antibody mediated rejection (AMR) and poor clinical outcomes after lung transplant (LT). Intravenous immune…
  • 2021 American Transplant Congress

    Elexacaftor/ivacaftor/tezacaftor in Lung Transplant Recipients: A Case Series

    L. M. Potter1, B. Vargas2, S. M. Rotolo1, C. McEwen1, K. Tsui1

    1University of Chicago Medicine, Chicago, IL, 2Roosevelt University, Chicago, IL

    *Purpose: Little data is published describing the safety or efficacy of elexacaftor/ivacaftor/tezacaftor in lung transplant recipients. Even though it is not expected to offer pulmonary…
  • 2021 American Transplant Congress

    Liver Simulated Allocation Model Does Not Accurately Predict Organ Offer Decisions in Pediatric Liver Transplant Candidates

    N. L. Wood1, D. B. Mogul2, E. K. Hsu3, E. R. Perito4, G. V. Mazariegos5, D. Vanderwerken1, D. L. Segev2, S. Gentry1

    1US Naval Academy, Annapolis, MD, 2Johns Hopkins, Baltimore, MD, 3Univ of Washington, Seattle, WA, 4UCSF, San Francisco, CA, 5Univ of Pittsburgh, Pittsburgh, PA

    *Purpose: The U.S. relies on the Scientific Registry of Transplant Recipient’s (SRTR’s) Liver Simulated Allocation Model (LSAM) to predict the effect of allocation policy changes…
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