Abstracts Archive - Page 291 of 1683 - ATC Abstracts

2021 American Transplant Congress
Prevalence of Diabetic Changes on Kidney Allograft Biopsies of Normoglycemic Simultaneous Pancreas-Kidney Transplant Recipients
C. Mejia, G. Giannini, D. C. Brennan, A. Rosenberg, S. Alasfar
Johns Hopkins University, Baltimore, MD
*Purpose: Small studies suggest that achieving normoglycemia with simultaneous pancreas-kidney transplant (SPK) prevents the development of diabetic nephropathy (DN) among type 1 diabetics (T1DM). However,…
2021 American Transplant Congress
Trends in Mortality Among Solid Organ Transplant Recipients Hospitalized for Covid-19 During the Course of the Pandemic
M. R. Heldman, O. S. Kates, R. M. Rakita, E. D. Lease, C. E. Fisher, A. P. Limaye
University of Washington, Seattle, WA
*Purpose: Actual and comorbidity-adjusted mortality in hospitalized patients with COVID-19 has declined in the general population during the course of the pandemic. Whether a similar…
2021 American Transplant Congress
Treg Engagement of Lymphotoxin Beta Receptor in Lymphatic Endothelial Cells is Required for Allograft Protection
V. Saxena¹, W. Piao¹, L. Li¹, Y. Xiong¹, M. W. Shirkey¹, J. Iyyathurai¹, R. Lakhan¹, R. Abdi², J. Bromberg¹
¹U Maryland, Baltimore, MD, ²Harvard U, Boston, MA
*Purpose: Sequential migration of regulatory T cells (Treg) from graft to afferent lymphatics and lymph nodes (LN) is needed for Treg suppressive function. Migration requires…
2021 American Transplant Congress
Simultaneous Pancreas-Kidney Transplantation in Caucasian versus African American Patients: Does Recipient Ethnicity Influence Outcomes?
J. Rogers¹, A. Farney², G. Orlando², C. Jay², K. Gurung², B. Sharda², A. Reeves-Daniel³, A. Mena-Gutierrez³, N. Sakhovskaya³, W. Doares⁴, S. Kaczmorski⁴, M. Magid⁴, M. Gautreaux², R. Stratta²
¹Wake Forest Baptist Medical Center, Winston-Salem, NC, ²Department of Surgery, Wake Forest Baptist Medical Center, Winston-Salem, NC, ³Internal Medicine, Wake Forest Baptist Medical Center, Winston-Salem, NC, ⁴Department of Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC
*Purpose: The influence of African American (AA) recipient ethnicity on outcomes following simultaneous pancreas-kidney transplantation (SPKT) in the modern era is uncertain.*Methods: From 11/01 to…
2021 American Transplant Congress
A Multimodal Interrogation of Human Renal Allografts
D. Dadhania¹, R. Ding¹, H. Xu², C. Lee¹, C. Snopkowski¹, T. Salinas¹, T. Muthukumar¹, J. Lee¹, R. Woodward², M. Grskovic², S. Dholakia², M. Suthanthiran¹
¹Weill Cornell Medicine - NYPH, New York, NY, ²CareDx, New York, NY
*Purpose: Development and validation of noninvasive biomarkers of kidney allograft rejection should improve transplant outcomes. CTOT-04 study validated urinary cell mRNA signature (CTOT04-Sig) for T-cell…
2021 American Transplant Congress
A Molecular Classifier Identifies Antibody-Mediated Rejection-Associated Changes in Lung Transplant Biopsies
K. S. Madill-Thomsen¹, K. M. Halloran², M. Parkes¹, P. F. Halloran¹, &. the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Identifying lung transplant antibody-mediated rejection (ABMR) has been controversial. We compared gene expression in donor-specific antibody (DSA) positive vs. DSA negative lung transbronchial biopsies…
2021 American Transplant Congress
Leflunomide Therapy for Treatment of Bk Viremia in Pediatric Kidney Transplant Recipients
A. Aldieri¹, M. Chandran², D. Matossian³, B. Magella⁴, D. Lazear⁴, M. Bock², E. Blanchette²
¹Children's Hospital Colorado, Denver, CO, ²Children's Hospital Colorado, Aurora, CO, ³Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ⁴Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: BK viremia (BKV) after kidney transplantation (KT) poses significant risk for BK virus-associated nephropathy (BKVN) and impacts graft survival. Conventional treatment involves reduction of…
2021 American Transplant Congress
The Evolution of the National Liver Review Board
S. Noreen¹, J. Trotter², J. Pomposelli³, M. Cafarella¹, J. Heimbach⁴
¹UNOS, Richmond, VA, ²BSWHealth, Dallas, TX, ³UCHealth, Aurora, CO, ⁴Mayo Clinic, Rochester, MN
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2021 American Transplant Congress
Increasing Survival on the Kidney Transplant Waiting List: A Thirty-Three Year Analysis
E. L. Godfrey¹, P. T. Kambhampati¹, J. A. Goss², A. Rana²
¹Baylor College of Medicine, Houston, TX, ²Division of Abdominal Transplantation, Department of Surgery, Baylor College of Medicine, Houston, TX
*Purpose: The shortage of available donor kidneys remains the greatest obstacle to transplantation, with many patients spending years on the transplant list. During this time,…
2021 American Transplant Congress
Profound Opportunities Lost: Patients with High Priority for Ideal Donor Kidneys That are Not Placed on the Kidney Transplant Waiting List
J. Schold¹, A. Huml¹, E. Poggio¹, J. Sedor¹, S. Husain², K. L. King², S. Mohan²
¹Cleveland Clinic Foundation, Cleveland, OH, ²Columbia University, New York, NY
*Purpose: The national Kidney Allocation System(KAS) prioritizes patients with high (top 20%) Estimated Post-Transplant Survival (EPTS) with expedited access to high quality deceased donor kidneys.…