Abstracts Archive - Page 282 of 1683 - ATC Abstracts

2021 American Transplant Congress
Impact of a “COVID-free” Pathway on Living Donor Transplantation During a Pandemic
S. Koganti, Y. Cheah, C. J. Simon, M. Tobon Lascano, J. Kim, M. E. Akoad
Lahey Hospital & Medical Center, Burlington, MA
*Purpose: COVID-19 pandemic has significantly decreased rates of organ transplantation, with most programs curtailing living donor transplantations. This has led to an increase in waitlist…
2021 American Transplant Congress
Implementation of a High-risk Medication Report for Waitlisted Liver Transplant Candidates
M. M. Eiting¹, H. Yeh², M. Cote¹, S. Shao¹, A. B. Scherrer², L. Dageforde², N. Elias², C. Rogers Marks¹
¹Pharmacy, Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Boston, MA
*Purpose: Use of high-risk medications (HRMs) at the time of liver transplant may lead to delays in surgery or peri-operative complications (bleeding, drug-drug interactions (DDI),…
2021 American Transplant Congress
Myeloid Foxo1-β-catenin Axis Regulates Hedgehog/Gli1 Signaling and Controls NLRP3-Mediated Innate Immune Responses in Sterile Inflammatory Liver Injury
D. Xu, C. Li, M. Sheng, Y. Lin, Y. Tian, Y. Zhan, A. J. Coito, R. W. Busuttil, D. G. Farmer, J. W. Kupiec-Weglinski, B. Ke
Surgery, Dumont - UCLA Transplant Center, Los Angeles, CA
*Purpose: Foxo1 plays important roles in cell metabolism, oxidative stress, inflammation, and apoptosis. Activation of Hedgehog/Gli1 signaling regulates cell growth, differentiation, and immune function. However,…
2021 American Transplant Congress
Twelve Live Births After Uterus Transplantation in the Dallas Uterus Transplant Study
L. Johannesson, G. J. McKenna, A. Wall, J. Bayer, G. Testa
Baylor University Medical Center, Dallas, TX
*Purpose: To describe aggregated pregnancy outcomes after uterus transplantation from a single, experienced center.*Methods: This prospective study reports on live births among 20 women who…
2021 American Transplant Congress
Immunosuppression in Uterine Transplant Recipients: Experience from the Largest Uterine Transplant Program
N. Wilson, R. Patel, L. Johannesson, G. Testa, T. Sam
Baylor University Medical Center at Dallas, Dallas, TX
*Purpose: Uterus transplantation (UT) is an emerging treatment in the field of total uterine infertility. There is no consensus on the optimal immunosuppression regimen in…
2021 American Transplant Congress
Donor Derived Transmissions 2019: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
L. Danziger-Isakov¹, M. G. Michaels¹, A. Agarwal¹, S. Aslam¹, K. Dunn¹, J. Goldman¹, D. Levine¹, C. Marboe¹, G. Marklin¹, S. Pouch¹, M. Rana¹, R. Razonable¹, H. L. Stevenson¹, H. S. Te¹, A. Woolley¹, E. Ward², C. Jett², L. Cartwright², R. La Hoz¹
¹OPTN DTAC, Richmond, VA, ²UNOS, Richmond, VA
*Purpose: The OPTN DTAC, a multidisciplinary group, evaluates potential donor derived transmission events (PDDTE), mostly infections (I) & malignancies (M), to assess the likelihood of…
2021 American Transplant Congress
A Noninvasive Diagnostic Approach for Molecular Monitoring of Face Transplant Recipients
C. Snopkowski¹, P. Rabbani², H. Yang¹, Z. Berman², G. Diep², C. Li¹, T. Muthukumar¹, R. Ding¹, D. Ceradini², M. Suthanthiran¹
¹Weill Cornell Medical Institute, Department of Medicine, Division of Nephrology, NY, NY, ²NYU Langone Health, Hansjörg Wyss Department of Plastic Surgery, NY, NY
*Purpose: Skin biopsies are currently the gold standard for evaluating the inflammatory status of face allografts. However, “tape stripping” is emerging as a noninvasive technique…
2021 American Transplant Congress
Precision Medicine Tools in Kidney Transplant (KTx): Implications for Individualized Immunosupression Therapy and Downstream Cost-savings
S. Anand, J. Sanchez-Garcia, L. Dong, M. Fife, J. Krong, D. Morris, T. Srinivas
Intermountain Medical Center, Murray, UT
*Purpose: Kidney Tissue Transcriptomics (Tr) is an emerging adjunct to traditional histology for diagnosis of kidney rejection in KTx. The objective assessment and reliance on…
2021 American Transplant Congress
Characterisation of Distinct Graft Infiltrates Following Cellular Therapy in Kidney Transplant Recipients
M. O. Brook¹, P. N. Harden², I. Roberts², W. R. Mulley³, J. Hester¹, M. E. Reinders⁴, F. Issa¹
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, ²Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, ³Department of Nephrology, Monash Medical Centre, Melbourne, Australia, ⁴Division of Nephrology and Transplant Center, Leiden University Medical Center, Leiden, Netherlands
*Purpose: Cellular therapy is an emerging treatment in the field of clinical transplantation with the potential to improve both short and long-term transplant outcomes. We…
2021 American Transplant Congress
Utility of Follow-up Biopsies After Acute Rejection in Pediatric Kidney Transplantation
S. S. Raza¹, V. Hauptfeld-Dolejsek¹, F. Rosenblum¹, E. C. Mroczek-Musulman², D. R. Kelly², M. Seifert¹
¹Department of Nephrology, UAB School of Medicine, Birmingham, AL, ²Children’s of Alabama, Birmingham, AL
*Purpose: Treatment of acute kidney transplant rejection in children is often guided by creatinine-based estimates of GFR (eGFR) that may lack sensitivity to determine the…