ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Utilization of Pre-Procurement Donor Liver Biopsy in Donation-after-circulatory-Death Liver Transplantation

    A. C. Bolognese1, N. Neidlinger1, C. Sparks2, A. Schneider2, A. M. D'Alessandro1, D. P. Foley1

    1Department of Surgery, Division of Transplantation, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2UW Organ and Tissue Donation, Madison, WI

    *Purpose: Careful selection of suitable DCD donor livers is critical to obtain optimal transplant outcomes. In order to identify potentially suitable livers prior to DCD…
  • 2021 American Transplant Congress

    Influence of Controlled Donation After Circulatory Death (cdcd) on Waiting List Mortalityfor Liver Transplantation in the Last 10 Years: The Spanish Experience

    F. Alconchel, M. Royo-Villanova, J. Moya, L. Martínez-Alarcón, J. Zambudio, P. Cascales-Campos, T. Nicolás, R. Robles, F. Sánchez-Bueno, J. Pons, J. Rodríguez, A. Ríos, J. Fernández, P. Ramírez

    University Hospital Virgen Arrixaca (IMIB-Arrixaca), Murcia, Spain

    *Purpose: Controlled donation after circulatory death (cDCD) provides one third of liver donors in Spain nowadays. The aim of our work is to evaluate the…
  • 2021 American Transplant Congress

    Machine Learning Informs Utility-Based Non-Directed Living Liver Donor Allocation

    K. Bambha1, J. Perkins1, M. Sturdevant1, S. W. Biggins1, R. Bakthavatsalam1, P. Healey2, A. Dick2, J. Reyes1

    1University of Washington, Seattle, WA, 2Seattle Children's, Seattle, WA

    *Purpose: To maximize non-directed living liver donor graft utility, we developed analytic models predicting 10-year graft survival post liver transplant (LT).*Methods: We analyzed OPTN living…
  • 2021 American Transplant Congress

    No Benefit of Antithymocyte Globulin in Living Donor Liver Transplant Recipients

    N. Wilson, P. Nguyen, G. Saracino, R. Patel, G. Testa, T. Sam

    Baylor University Medical Center, Dallas, TX

    *Purpose: Acute rejection after liver transplant is associated with increased risk of graft failure and mortality. Reports on rejection rates in living donor liver transplants…
  • 2021 American Transplant Congress

    Short Waiting Time is Not Associated with Decrease in Disease-free Survival in Liver Transplant Recipients with HCC

    J. Daum1, N. Gupta1, B. Aqel2, L. Mi3, J. Harbell4

    1School of Medicine, Mayo Clinic Arizona, Phoenix, AZ, 2Hepatology, Mayo Clinic Arizona, Phoenix, AZ, 3Biostatistics, Mayo Clinic Arizona, Phoenix, AZ, 4Transplant Surgery, Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: Studies have suggested that shorter waiting times (WT) for liver transplant (LT) in patients with hepatocellular carcinoma (HCC) may be associated with increased HCC…
  • 2021 American Transplant Congress

    Time-averaged Oxygen Saturation During Donor Agonal Phase is Associated with Post-transplant Hepatic Graft Survival

    K. C. Eddinger1, E. M. Sonnenberg1, A. Kayastha2, N. Mahmud3, D. E. Schaubel2, P. L. Abt1

    1Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 3Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, PA

    *Purpose: Livers harvested from donors after cardiac death (DCD) are subjected to a period of relative warm ischemia during the agonal phase. There have been…
  • 2021 American Transplant Congress

    Excellent Pathological Response with Gemcitabine-based Protocol in Patient with Hilar Cholangiocarcinoma

    A. Saharia1, R. McMillan1, S. Kodali1, M. Javley2, C. M. Mobley1, M. J. Hobeika1, A. Shetty1, D. W. Victor1, R. McFadden1, M. Abdelrahim1, K. Heyne1, A. O. Gaber1, R. M. Ghobrial1

    1Houston Methodist Hospital, Houston, TX, 2MD Anderson Cancer Center, Houston, TX

    *Purpose: The standard treatment for hilar cholangiocarcinoma is using 5FU along with brachytherapy and external beam radiation. The downside of this regimen is the uncertain…
  • 2021 American Transplant Congress

    Biliary Complications Following Adult Deceased Donor Liver Transplantation: Risk Factors and Implications at a High-Volume US Center

    A. Matar, K. Ross-Driscoll, L. Kenney, H. Wichmann, J. F. Magliocca, W. H. Kitchens

    Emory Transplant Center, Atlanta, GA

    *Purpose: Biliary leaks and anastomotic strictures comprise the majority of biliary complications (BCs) following liver transplantation. Most case series of BCs in adult deceased donor…
  • 2021 American Transplant Congress

    The Role of Histone Acetylation/methylation Mediated Epigenetic Modifications in the Pathogenesis of Non-alcoholic Steatohepatitis-associated Liver Carcinogenesis

    P. K. Rajan1, U. Utibe-Abasi1, J. D. Sanabria1, M. Banerjee2, G. Smith1, M. S. Schade1, J. Sanabria1, K. Sodhi1, S. Pierre2, Z. Xie2, J. I. Shapiro2, J. Sanabria1

    1Department of Surgery, Marshall University, Huntington, WV, 2Marshall Institute for Interdisciplinary Research (MIIR), Marshall University, Huntington, WV

    *Purpose: Hepatocellular carcinoma (HCC) is one of the most aggressive human cancers and is characterized by an acquisition of multiple abnormal phenotypes driven by epigenetic…
  • 2021 American Transplant Congress

    Association of Donor-Derived Cell-Free DNA with Severity of Interstitial Fibrosis and Cortical Atrophy Lesions Following Kidney Transplantation

    L. Bu1, E. Stites2, V. Bowers3, T. Alhamad4, J. S. Bromberg5, G. Gupta6, I. Moinuddin6, S. Ghosh7, W. Tian7, A. Pai8, S. Anand9

    1University of Minnesota, Minneapolis, MN, 2University of Colorado, Aurora, CO, 3Tampa General Hospital, Tampa, FL, 4Washington University in St. Louis, St. Louis, MO, 5University of Maryland School of Medicine, Baltimore, MD, 6Virginia Commonwealth University, Richmond, VA, 7CareDx, Brisbane, CA, 8University of Texas McGovern Medical School, Houston, TX, 9Intermountain Medical Center, Murray, UT

    *Purpose: The most common cause of kidney transplant (KT) failure is the poorly characterized histopathologic entity “interstitial fibrosis and tubular atrophy” (IFTA). There are no…
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