Abstracts Archive - Page 22 of 1683 - ATC Abstracts

2022 American Transplant Congress
Are Autoimmune Conditions Disadvantaged Compared to Alcoholic Cirrhosis and Hepatocellular Carcinoma?
S. S. Keeling
Baylor College of Medicine, Houston, TX
*Purpose: Orthotopic liver transplantation (OLT) is a lifesaving therapy for patients with irreversible liver damage caused by autoimmune liver diseases (ALD) including autoimmune hepatitis (AIH),…
2022 American Transplant Congress
Bionic Pancreas – The First Results of Functionality of 3D-Bioprinted Bionic Tissue Model Transplantation with Pancreatic Islets
M. Klak¹, M. Wszola¹, A. Berman¹, A. Filip¹, A. Kosowska², J. Olkowska-Truchanowicz², G. Tymicki¹, M. Rachalewski¹, T. Bryniarski¹, M. Kolodziejska¹, T. Dobrzanski³, D. Ujazdowska¹, J. Wejman⁴, I. Uhrynowska-Tyszkiewicz², A. Kaminski²
¹Foundation of Research and Science Development, Warsaw, Poland, ²Medical University of Warsaw, Warsaw, Poland, ³Polbionica Ltd., Warsaw, Poland, ⁴Center for Pathomorphological Diagnostics Ltd, Warsaw, Poland
*Purpose: Tissue engineering is currently on advanced stage of development which gives a possibilities for novel strategy of personal treatment of type 1 diabetes. AIM:…
2022 American Transplant Congress
Repeat Kidney Transplantation from Living Donors Offers Comparable Outcomes as First Transplantation
N. Oh, K. Lee, J. Rhu, J. Kim, G. Choi, J. Park, J. Joh
Department of Surgery, Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The number of patients relisted for repeat kidney transplantation is increasing due to prolonged survival after first transplantation. This study is designed to compare…
2022 American Transplant Congress
A Patient and Family Decision Support Tool for Kidney Organ Offer Decisions
C. Schaffhausen¹, A. Hart², S. Chu³, A. K. Israni², J. Synder¹
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²Hennepin Healthcare / University of Minnesota, Minneapolis, MN, ³University of Minnesota, Saint Paul, MN
*Purpose: For kidney transplant candidates and their care team, deciding to accept a donor organ with known or potential risk factors can be stressful and…
2022 American Transplant Congress
Donor-Derived Cell-Free DNA Testing in Kidney Transplantation: Do One-Month Values Have Any Prognostic Significance?
B. K. Sharda¹, M. Garner¹, A. Farney¹, G. Orlando², J. Rogers², C. Jay³, A. Daniel¹, A. Guiterrez¹, N. Sakhovskaya¹, R. Stratta¹
¹ATRIUM HEALTH Wake Forest Baptist Medical Center, Winston Salem, NC, ²Wake Forest Baptist Medical Center, Winston Salem, NC, ³Wake Forest Baptist Health, Winston-Salem, NC
*Purpose: Plasma-based donor-derived cell-free DNA (dd-cfDNA) assays have been proposed as an alternative to percutaneous renal allograft biopsy which is the current gold standard for…
2022 American Transplant Congress
Pegloticase for Uncontrolled Gout in Kidney Transplant Recipients: Provisional Data Report of a Multicenter, Open-Label, Efficacy and Safety Study
A. Abdellatif¹, L. Zhao², K. Cherny², B. Marder², J. D. Scandling³, K. Saag⁴
¹Division of Nephrology, Baylor College of Medicine, Houston, TX, ²Horizon Therapeutics PLC, Deerfield, IL, ³Division of Nephrology, Stanford School of Medicine, Stanford, CA, ⁴Division of Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
*Purpose: Gout in kidney transplant (KT) recipients can be severe and particularly challenging to manage. Pegloticase co-therapy with immunomodulators improved urate lowering therapy (ULT) response…
2022 American Transplant Congress
Bisphosphonates for Fracture Prevention in Kidney Transplant Recipients
J. Kahwaji¹, S. Yang², J. Sim³
¹Nephrology/Transplant, Kaiser Los Angeles Medical Center, Los Angeles, CA, ²Research and Evaluation, Kaiser-Permanente, Pasadena, CA, ³Nephrology, Kaiser Los Angeles Medical Center, Los Angeles, CA
*Purpose: Kidney transplant recipients are at increased risk of fracture, however bisphosphonate use has not be shown to lower fracture risk in this population. We…
2022 American Transplant Congress
Long-Term Kidney Allotransplant Acceptance is Defined by a Shift from a T Cell to a B Cell Rich Immune Microenvironment Within the Graft
E. S. Szuter¹, T. Yokose¹, M. T. Guinn¹, J. Ge², I. Rosales³, B. Kwon⁴, P. S. Russell¹, A. Cuenca², D. Kreisel⁵, P. Sage⁶, J. C. Madsen¹, R. B. Colvin³, A. Alessandrini¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, ²Department of Surgery, Boston Children's Hospital, Boston, MA, ³Department of Pathology, Massachusetts General Hospital, Boston, MA, ⁴Harvard College, Cambridge, MA, ⁵Department of Surgery, Washington University, St. Louis, MO, ⁶Transplantation Research Center, Renal Division, Brigham and Women’s Hospital, Boston, MA
*Purpose: Mouse kidney allografts are spontaneously accepted in select, fully-mismatched donor-recipient strain combinations, such as DBA/2J to C57BL/6 (B6). Tolerant renal grafts develop aggregates of…
2022 American Transplant Congress
Costs Associated with Induction Therapy for Pediatric Kidney Transplantation
N. M. Rodig¹, H. Pizzo², D. Levy Erez³, T. Richardson⁴, M. Somers¹
¹Boston Children's Hospital, Boston, MA, ²Cedars-Sinai Medical Center, Los Angeles, CA, ³Children’s Hospital of Philadelphia, Philadelphia, PA, ⁴Children's Hospital Association, Lenexa, KS
*Purpose: Choice of induction agent for pediatric kidney transplantation (KTx) is often based upon patient characteristics and center practice; costs associated with this choice have…
2022 American Transplant Congress
Single Cell RNAseq Analysis of Liver Transplant Rejection Reveals Highly Restricted TCR Clonal Expansion of Tissue-Resident Memory CD8⁺ T Cells That Persist Despite Corticosteroids and ATG Therapy
A. L. Peters¹, G. Begum¹, K. Roskin², E. Woodle³, D. Hildeman⁴
¹Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Department of Bioinformatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Department of Surgery, University of Cincinnati, Cincinnati, OH, ⁴Department of Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: Conventional therapy for liver transplant rejection (corticosteroids and ATG) has remained unchanged for six decades, and is not infrequently met with treatment failure. Here,…