2013 American Transplant Congress
IL21 Plays a Critical Role in Chronic Rejection but Not in Acute or Accelerated Allograft Rejection
University of Toledo College of Medicine, Toledo
There is mounting evidence that IL21 may be a specialized cytokine that controls chronic rather than acute immune responses. Herein, we evaluated the role of…2013 American Transplant Congress
Monocyte FcγRIIa Allotype Influences Recruitment to Endothelial Cells Triggered by HLA I Antibodies
Pathology and Laboratory Medicine, UCLA, Los Angeles, CA
Background: HLA I antibody (Ab) activation of endothelial cells (EC) promotes monocyte recruitment through P-selectin and FcΓRI and FcΓRIIa. Human FcΓRIIa is dimorphic. R131 allele…2013 American Transplant Congress
Characterization of Novel Human Transitional B Cell Subsets and Their Significance in Renal Transplantation
We have shown that human transitional B cells are polarized towards regulatory cytokine expression and suppress pro-inflammatory Th1 response by autologous T cells. These cells…2013 American Transplant Congress
Prevention of Poor Psychosocial Outcomes in Living Kidney and Liver Donors: Feasibility and Efficacy in a Randomized Controlled Trial
University of Pittsburgh, Pittsburgh; Carnegie Mellon University, Pittsburgh
Background: Although many living organ donors experience no adverse psychosocial consequences of donation, others develop enduring somatic symptoms, psychological distress, and interpersonal difficulties. There are…2013 American Transplant Congress
Outcomes of Adult Dual Kidney Transplants by KDRI in the United States
Background: Current UNOS guidelines do not provide adequate discrimination of kidneys that should be transplanted as single versus dual. To better define selection of kidneys…