2013 American Transplant Congress
Most Late Kidney Graft Failures after Simultaneous Kidney-Pancreas Transplant (SPK) Are Due to Non-Immunological Graft Injury
Background: Late allograft failure is one of the critical issues in renal transplantation today. The relative importance of immunological versus non-immunological causes of chronic kidney…2013 American Transplant Congress
Endodermal Precursor Cells Derived from Embryonic Stem Cells Can Engraft in Mouse Liver
Surgery, University of Florida, Gainesville, FL
Purpose: Embryonic stem (ES) cells have been shown to have great value therapeutically due to their limitless capacity for self-renewal and proliferation, and their ability…2013 American Transplant Congress
Immune Cell Derived C3a and C5a Mediate Human Alloreactive T Cell Immunity
Renal Division, Department of Medicine, Mount Sinai School of Medicine, New York, NY
Background: Murine studies showed immune cell derived C3a/C5a are costimulatory intermediaries required for T cell activation. We investigated how these concepts apply to human alloreactive…2013 American Transplant Congress
Role of Eosinophils in the Induction and Maintenance of the Alloantibody Response, The
Department of Medicine, Mount Sinai School of Medicine, New York
Background: Delineating mechanisms of alloantibody formation and maintenance could guide development of novel therapies aimed at treating antibody mediated transplant rejection. Published work from 2011…2013 American Transplant Congress
Spectrum of Renal Pathology and Gene Expression Profiles of Kidney Biopsies in Patients with Cirrhosis Listed for Liver Transplantation
Transplantation, Montefiore Medical Center, Bronx, NY
Introduction: We previously demonstrated universal glomerular abnormalities in kidney biopsies after orthotopic liver transplantation (OLT). We hypothesize that these changes exist prior to OLT and…2013 American Transplant Congress
Unique Role of Antibodies to MHC Class I in the Induction of Inflammatory Cellular Infiltration: Selective Role for CD4 and CD8 Cells in Development of Autoimmunity and Obliterative Airway Disease
Surgery, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
Background: Anti-MHC class I administration into lungs results in cellular infiltration, epithelial damage, immune responses to lung associated self-antigens(SAgs), KΑ1 tubulin (KΑ1T) and Collagen V…2013 American Transplant Congress
NASH Recurrence: Focus on Preventing New Onset Diabetes?
Pharmacy, MUSC, Charleston, SC; Transplant, MUSC, Charleston, SC
Background: The aim of this study was to evaluate the risk factors and associated outcomes with NASH recurrence following liver transplant.Methods: Single center retrospective longitudinal…2013 American Transplant Congress
Development of De Novo Anti-HLA Antibodies after Treatment with/without Rituximab, a B Cell−Depleting Treatment
Urology, 8-1 Kawada-Cho, Shinjuku-ku, Tokyo, Japan
Background: Organ shortages have forced a widening of the indications for kidney donors. In Japan, ABO-incompatible kidney transplantation (ABOi) is a popular alternative to deceased…2013 American Transplant Congress
Monoclonal Antibody Which Possibly May Replace the Therapeutic Intravenous Immunoglobulin, A
HLA Antibodies, Terasaki Foundation Laboratory, Los Angeles, CA
The value of intravenous immunoglobulin (IVIg) in lowering HLA antibodies (Abs) has recently come into question. High variability in different therapeutic preparations may account for…2013 American Transplant Congress
Prevalence of Human Papillomavirus (HPV) Infection in Female Kidney Transplant Recipients
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, DF, Mexico
Introduction: Kidney transplant recipients are at higher risk for viral infection-related cancers. Even though HPV infection is strongly associated with several genital cancers, data on…
American Transplant Congress abstracts