ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Multicenter Evaluation of Efficacy and Safety of Valganciclovir 450 mg/day vs. 900 mg/day for Prevention of Cytomegalovirus Disease in Donor and Recipient Positive (D+/R+) Renal Transplant Recipients

    S. Gabardi, R. Cross, K. DePiero, T. Dick, K. Ferguson, E. Newkirk, J. Park, E. Tichy, K. Ueda, R. Weng, S. Heldenbrand

    Multicenter CMV Pharmacists Collaborative Study Group, Boston

    The cytomegalovirus (CMV) donor-positive/recipient-positive (D+/R+) population represents the largest proportion of renal transplant recipients (RTR). Current practice guidelines on the prevention of CMV recommend antiviral…
  • 2013 American Transplant Congress

    Flow Crossmatching for Renal Transplantation in the Virtual Crossmatch Era: Fifty Shades of Grey

    R. Cirocco, J. Mendiolina, L. Biondi, M. Moritz

    HLA Laboratory and the Transplant Center, Lehigh Valley Health Network, Allentown, PA

    Every transplant team wants a definitive answer for the compatibility of a potential recipient with a specific donor. The Mean Equivalent Standard Fluorescence is a…
  • 2013 American Transplant Congress

    Evidence for Renal Tubular Epithelial Cells as Another Source of IL-17 Producing Cells

    H. Zhou, L. Xue, Y. Wang, J. Liu, L. Zhang, J. Yu

    Urologic Diseases Center, The First Bethune Hospital, Jilin University, Changchun, Jilin, China; Key Laboratory of Pathobiology, Ministry of Education, School of Basic Medical Sciences, Jilin University, Changchun, Jilin, China; Urologic Surgery Department, Laigang Hospital,Taishan Medical University, Taishan, Shandong, China

    Interleukin-17(IL-17) is mainly produced by a subset of CD4+T cells (TH17) .The exact source of IL-17 expression in renal graft during rejection remians unclear. A.Loverre…
  • 2013 American Transplant Congress

    Development of De Novo Anti-HLA Abs in Kidney Transplant Recipients: Final Analysis of the NIH CTOT02 Study

    A. Chandraker, I. Guleria, D. Ikle, H. Chin, F. Vincenti, Y. Morrison, N. Bridges, W. Harmon, M. Sayegh

    Brigham and Women's Hospital and Boston Children's Hospital, Harvard Medical School, Boston; RHO, Chapel Hill, NC; UCSF, San Francisco; NIH, Bethesda, MD

    The NIH CTOT02 is the first large multi-center prospective study to examine the causes and effects of development of post-transplant de novo anti-HLA Ab in…
  • 2013 American Transplant Congress

    Successful Reduction and Cessation of Immunosuppressants by a Regulatory T Cell-Based Cell Therapy in Living Donor Liver Transplantation: A Pilot Study for Tolerance Induction

    K. Yamashita, M. Zaitsu, A. Nagatsu, R. Goto, T. Oura, M. Watanabe, T. Aoyagi, T. Suzuki, T. Shimamura, N. Sato, J. Sugita, K. Hatanaka, M. Taniguchi, H. Furukawa, H. Bashuda, K. Okumura, S. Todo

    Hokkaido University, Sapporo, Japan; Asahikawa Medical College, Asahikawa, Japan; Juntendo University, Tokyo, Japan

    Purpose: Life-long use of immunosuppressants (IS) is associated with significant immunological and non-immunological adverse effects. Thus, minization, followed by complete cessation of IS has been…
  • 2013 American Transplant Congress

    Nanostructural Alteration of Blocking Activation of CD8+ T Cells Utilizing Atomic Force Microscopy

    H. Ahn, B. Kim, S. Joo, Y. Lee, G. Lee, H. Park

    Department of Surgery, School of Medicine, Kyung Hee University, Seoul, Korea; Department of Biomedical Engineering, School of Medicine, Kyung Hee University, Seoul, Korea

    PurposeThis research investigated the nanostructural alterations in blocking T cell activation using atomic force microscopy (AFM).MethodsCD8+ T cells were isolated from the spleens of C57BL/6…
  • 2013 American Transplant Congress

    Does Length of Hospital Stay and Hospital-Wide Incidence Have an Impact on Clostridium Difficile Infection (CDI) in Organ Transplant Recipients?

    J. Deyo, J. Huang, M. Wheeler, R. Lee, T. Zeynep, R. Dupuis, T. Kozlowski

    University of North Carolina, Chapel Hill

    Several risk factors contributing to CDI have been identified in organ transplant recipients (Txs)(Transplantation 2012; 93:1051-57). Among these factors is hospital length of stay (LOS).…
  • 2013 American Transplant Congress

    Serum and Urine IP–10 and Fractalkine Are Effective Biomarkers for Prediction of Early Kidney Transplant Rejection

    Z. Jin, P. Tian, W. Xue, C. Ding, J. Zheng, W. Duan, T. Mao, M. Xi

    Department of Kidney Transplantation, Hospital of Nephropathy, First Affiliated Hospital of MedicalCollege, Xi'an Jiaotong University, Xi'an, China

    Background: Chemotactic factors play an important role in acute rejection. The aims of our study were to examine the expression of serum and urine IP-10…
  • 2013 American Transplant Congress

    Improving the SRTR Methodology Used To Identify Potentially Underperforming Transplant Programs in the United States

    N. Salkowski, E. Edwards, T. Leighton, A. Israni, B. Kasiske, J. Snyder

    Scientific Registry of Transplant Recipients, Minneapolis Medical Research Foundation, Minneapolis, MN; United Network for Organ Sharing, Richmond, VA

    In Feb. 2012, SRTR and OPTN jointly hosted a consensus conference on transplant program quality and surveillance. One recommendation was to study Bayesian hierarchical modeling…
  • 2013 American Transplant Congress

    What Are the Outcomes from Very Old DCD Kidneys?

    P. Laftsidis, L. Szabo, E. Ablorsu

    Cardiff Nephrology and Transplantation Unit, UHW, Cardiff, United Kingdom

    Introduction:Kidney transplantation from elderly donors is still a very controversial topic. In recent years, we have seen an increase in the number of elderly DCD…
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