Abstracts Archive - Page 164 of 1683 - ATC Abstracts

2022 American Transplant Congress
Performance of Updated Estimated Glomerular Filtration Rate Equations in Black Living Kidney Donor Candidates
J. Augustine, A. Liaqat, S. Arrigain, J. Schold, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: New estimated glomerular filtration rate (eGFR) equations using serum creatinine (Cr) and/or cystatin C (CysC) have been derived to eliminate adjustment by perceived Black…
2022 American Transplant Congress
Portal Vein Challenges in Pediatric Liver Transplantation: The Utility of Interposition Grafts as an Acceptable Management Strategy
K. Etesami¹, R. Hogen², J. Cervantes³, Y. Kwon⁴, S. Zielsdorf³, J. Emamaullee³, Y. Genyk³
¹Surgery, Children's Hospital Los Angeles, Los Angeles, CA, ²University of Southern California, West Hollywood, CA, ³University of Southern California, Los Angeles, CA, ⁴Hepatobiliary and Abdominal Transplant Surgery, University of Southern California, Los Angeles, CA
*Purpose: Portal vein (PV) anomalies and portal vein thrombosis (PVT) can present as challenging cases in the pediatric cohort, necessitating analysis and an algorithmic approach.*Methods:…
2022 American Transplant Congress
The Impact of Tacrolimus Trough Variability on Acute Rejection Following Lung Transplantation
K. Evans¹, K. Beermann¹, H. Lee², M. Harris¹, C. W. Frankel³, H. Berry¹, H. Ali³
¹Pharmacy, Duke Health, Durham, NC, ²Biostatistics and Bioinformatics, Duke University, Durham, NC, ³Pulmonary, Allergy, and Critical Care, Duke Health, Durham, NC
*Purpose: This study aimed to evaluate the association of tacrolimus coefficient of variation (CV) with biopsy-proven acute cellular rejection in the first year following lung…
2022 American Transplant Congress
A Machine Learning Approach to Estimating Anticipated Waiting Time and Survival Benefit in Older Kidney Transplant Candidates
D. M. Vock¹, E. S. Helgeson², A. J. Matas²
¹University of Minnesota, Minneapolis, MN, ²U MN, Mpls, MN
*Purpose: Older kidney transplant (ktx) recipients face worse post-transplant survival due to increasing age and more comorbidities. Simultaneously, older ktx candidates are more likely to…
2022 American Transplant Congress
Proteome Profiling of Recurrent Primary Focal Segmental Glomerulosclerosis (FSGS) Plasma Samples Reveals Potential Proteins Involved in Primary FSGS
L. Gallon¹, N. Ahsan², V. Mas³, J. Leventhal¹, L. Fornelli²
¹Northwestern Univ NMFF, Chicago, IL, ²Mass Spectrometry, Proteomics and Metabolomics Core Facility, Department of Chemistry and Biochemistry, The University of Oklahoma, Oklahoma, OK, ³University of Maryland, Baltimore, MD
*Purpose: The presumed etiology of primary FSGS is a plasma factor that results in general podocyte dysfunction with partial and/or unpredictable response to immunosuppressive therapy…
2022 American Transplant Congress
Impact of Biliary Reconstruction on Tacrolimus Absorption in Pediatric Liver Transplant
M. Chandran¹, D. Yoeli¹, A. Sater², M. Adams¹, F. Karrer¹
¹Children's Hospital Colorado, Aurora, CO, ²University of Colorado, Aurora, CO
*Purpose: Tacrolimus (FK506) oral bioavailability in pediatric liver transplant recipients (LTR) is poor. Enteral FK506 is primarily absorbed in the small intestine and subject to…
2022 American Transplant Congress
Navigating the Ethics of Transplant Research Involving Newly Deceased
B. Parent¹, T. Schiff², E. Weldon³, N. Lawson⁴, S. Mehta⁵, R. A. Montgomery⁶
¹Medical Ethics, NYU Grossman School of Medicine, New York, NY, ²Medical Ethics, NYU School of Medicine, New York, NY, ³NYU Langone Health-Transplant Institute, New York, NY, ⁴NYU Langone Transplant Institute, New York, NY, ⁵New York University Langone Transplant Institute, New York, NY, ⁶NYU Langone, New York, NY
*Purpose: The most promising innovations for overcoming the organ shortage include novel organ sources such as xenotransplant and bioengineered organs. Studying these organs in mechanically…
2022 American Transplant Congress
PD-1 Expression on CD8+ T Cells Contributes to the Establishment of Mixed Chimerism-Based Operational Tolerance
C. J. Little, S. C. Kim, J. Fechner, J. Post, M. Winslow, D. B. Kaufman
Surgery, University of Wisconsin, Madison, WI
*Purpose: PD-1 is a T cell co-inhibitory molecule involved in T cell exhaustion and antigen specific hypo-reactivity. Given the role of PD-1 signaling in the…
2022 American Transplant Congress
B and Plasma Cell Populations Drive Chronic Rejection After Lung Transplantation
M. Bueno¹, N. F. Smirnova², K. Riemondy³, P. Suresh¹, M. Brown¹, X. Wang¹, S. Collins⁴, J. Sembrat¹, M. Koenigshoff¹, M. Snyder¹, J. McDyer¹, O. Eickelberg¹
¹Pulmonary and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, ²I2MC, INSERM UMR1297, Toulouse, France, ³Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO, ⁴Pulmonary Sciences and Critical Care Medicine, University of Colorado School of Medicine, Aurora, CO
*Purpose: Chronic lung allograft dysfunction (CLAD) remains the major determinant of morbidity and mortality post-lung transplantation (LTx). Bronchiolitis obliterans syndrome (BOS) is the most prevalent…
2022 American Transplant Congress
Does Black Race Modify the Risk of Transplant Failure Associated with HLA Mismatch in First Adult Kidney Allografts from Deceased Donors?
K. Atiemo
Tulane University, New Orleans, LA
*Purpose: Current US- based data suggests Black patients awaiting kidney re-transplantation are more likely to be highly sensitized compared to other races. Degree of HLA…