Abstracts Archive - Page 164 of 1683 - ATC Abstracts

2022 American Transplant Congress
Performance of Race-Independent GFR Estimating Formulas, CKD-EPI₂₀₂₁and NMR-GFR Post Kidney Transplantation
E. Schiffer¹, F. Stammler², M. Grassi², E. Schiffer²
¹Clinical Research, numares Group Corporation, Boston, MA, ²Research and Development, numares AG, Regensburg, Germany
*Purpose: Progressive GFR decline post kidney transplantation is a general problem that requires accurate assessment of GFR for clinical decision making. The gold-standard radiotracer determined…
2022 American Transplant Congress
Recoverability of Diabetic Nephropathy of Donor Kidney After Kidney Transplantation
K. Lee, J. Park
Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The natural course of diabetic donors on the outcome of kidney transplantation (KT) is controversial. The aim of this study was to analyze the…
2022 American Transplant Congress
Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients
R. Gordon¹, K. Dewey¹, R. Jariwala¹, B. Yen¹, J. Kukreja², S. Hays², J. Singer², R. Florez¹
¹Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA
*Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…
2022 American Transplant Congress
Detection of Alloreactive CD8+ T Cell Responses and the Immunopeptidome That Elicits Their Activation
A. B. Morris, X. Zhang, E. V. Peek, A. Hadley, C. Larsen
Emory University, Atlanta, GA
*Purpose: T cell-mediated rejection results in graft dysfunction and contributes to premature failure. Due to the complexity of the TCR:pMHC interaction, prediction of alloreactive T…
2022 American Transplant Congress
Performance of 2021 Creatinine and Cystatin C Based Equations without Race in Living Kidney Transplant Donors
A. Liaqat, H. Sawaf, L. Cholin, S. Arrigain, A. Wee, J. Schold, J. Augustine, E. Poggio
Cleveland Clinic, Cleveland, OH
*Purpose: New 2021 Creatinine (Cr) and Cystatin C (CysC) based GFR equations without the race factor have been refitted to perform better than either 2009…
2022 American Transplant Congress
A Pathway for Establishing Etiology of Kidney Failure: An Academic Transplant Center’s Experience with a Broad Kidney Gene Panel
R. Sodhi¹, K. Brossart², A. Desai¹, D. J. Arwindekar¹, H. Tabriziani², S. Akkina¹
¹Loyola University Medical Center, Maywood, IL, ²Natera, Inc., Austin, TX
*Purpose: Assessing genetic causes of kidney failure can inform pre-transplant decision making and may improve post-transplant outcomes. Here we describe an academic transplant center’s experience…
2022 American Transplant Congress
Natural Antibodies Are Associated With Rejection And Long-term Renal Allograft Loss In A Multi-center International Cohort
S. B. See¹, X. Yang², C. Burger³, B. Lamarthée⁴, R. Snanoudj⁵, R. Shihab¹, D. S. Tsapepas⁶, P. Roy¹, S. Larivière-Beaudoin⁷, K. Hamelin⁷, A. Mendoza Rojas⁸, N. M. van Besouw⁸, A. Bartosic⁹, N. Daniel⁹, E. R. Vasilescu¹⁰, S. Mohan¹¹, D. Cohen¹¹, L. Ratner¹¹, C. C. Baan⁸, J. S. Bromberg⁹, H. Cardinal⁷, D. Anglicheau³, Y. Sun², E. Zorn¹
¹CCTI, Columbia University Irving Medical Center, New York, NY, ²Biostatistics, Columbia University Irving Medical Center, New York, NY, ³Necker Hospital, Paris, France, ⁴Necker-Enfants Malades Institute, Paris, France, ⁵Bicêtre Hospital, Paris, France, ⁶Surgery, Columbia University Irving Medical Center, New York, NY, ⁷CHUM, Montreal, QC, Canada, ⁸Erasmus MC, Rotterdam, Netherlands, ⁹Surgery, University of Maryland School of Medicine, Baltimore, MD, ¹⁰Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY, ¹¹Medicine, Columbia University Irving Medical Center, New York, NY
*Purpose: Potentially harmful non-donor-specific human leukocyte antigen antibodies have been identified in renal transplantation, including natural IgG antibodies (Nabs) reactive to varied antigenic structures.*Methods: In…
2022 American Transplant Congress
Racial Barriers to Kidney Transplant After Listing, 2015 – 2020
W. T. McKinney¹, D. Schladt², J. Miller², T. Weaver², J. Pyke², T. Madhusoodanan³, A. K. Israni¹
¹Nephrology, Hennepin Healthcare Research Institute, Minneapolis, MN, ²Scientific Registry of Transplant Recipients, Minneapolis, MN, ³Nephrology, Hennepin Healthcare, Minneapolis, MN
*Purpose: We sought to evaluate racial disparities in access to deceased donor kidney transplant (DDKT) following changes to kidney allocation system (KAS) implemented in 2014.…
2022 American Transplant Congress
Predicting Long Term Kidney-Allograft Failure: Machine Learning vs Traditional Statistical Models
A. Truchot¹, M. Raynaud¹, c. lefaucheur², O. Aubert¹, A. Loupy¹
¹Paris Transplant Group, Paris, France, ²Hôpital Saint-Louis, Paris, France
*Purpose: Prognostic models have been developed in organ transplant over the past years using traditional statistical models. However, whether these are outperformed by machine learning…
2022 American Transplant Congress
A Decennial Summary of the OPTN Kidney Paired Donation Pilot Program
K. Gauntt¹, A. Toll¹, J. Musick¹, P. Kennealey², J. Kim³, T. Sandholm⁴, R. Leishman¹
¹United Network For Organ Sharing, Richmond, VA, ²University of Colorado Hospital, Aurora, CO, ³Keck Medicine of USC, Los Angeles, CA, ⁴Carnegie Mellon University, Pittsburgh, PA
*Purpose: The OPTN Kidney Paired Donation Pilot Program (KPDPP) is a national KPD system that has served the kidney transplant community for over 10 years.…