ATC Abstracts

American Transplant Congress abstracts

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  • 2013 American Transplant Congress

    Outcome Reporting in Randomised Controlled Trials (RCTs) of Primary Immunosuppression in Kidney Transplantation

    P. Masson, F. Duthie, P. Kelly, G. Higgins, J. Craig, A. Webster

    Sydney School of Public Health, University of Sydney, Sydney, NSW, Australia; Cochrane Renal Group, Centre for Kidney Research, Sydney, NSW, Australia; Department of Renal Medicine, Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom; Centre for Renal and Transplant Research, Westmead Hospital, Sydney, NSW, Australia

    Aims: To estimate the proportion of contemporary RCTs of primary immunosuppression in kidney transplantation reporting specified patient and graft-related outcomes, objectively measure reporting quality and…
  • 2013 American Transplant Congress

    Regulation of Serological Alloreactive Memory by Pathogen Infection, The

    R. Ruhil, O. Bulut, S. Talebagha, B. Oh, V. Lu, S. Knechtle, N. Iwakoshi

    Emory Transplant Center, Atlanta

    The breadth and strength of HLA specific antibodies (HSA) have a significant impact on waiting times for transplantation and the presence of HSA prior to…
  • 2013 American Transplant Congress

    Relationship of Kidney Length, Volume and Renal Split Function in Living Kidney Donors

    S. Fernandez, S. Mohan, Z. Zaky, J. Crew, J. Dube, M. Carrol, J. Wexler, L. Ratner, D. Cohen, B. Tanriover

    Nephrology, Columbia University Medical Center, New York, NY; Surgery, Columbia University Medical Center, New York, NY

    Purpose: All potential living donors at Columbia University Medical Center (CUMC) undergo abdominal CT imaging including estimation of kidney volume and length. Subjects with >…
  • 2013 American Transplant Congress

    Validating the Microarray Test for Antibody-Mediated Rejection in a Prospective Trial: The INTERCOM Study

    A. Pereira, J. Reeve, J. Chang, A. Matas, D. de Freitas, J. Bromberg, J. Sellares, G. Einecke, P. Halloran

    University of Alberta, Edmonton, Canada; University of Minnesota, Minneapolis; Manchester Royal Infirmary, Manchester, United Kingdom; University of Maryland School of Medicine, Baltimore; Hospital de la Vall d'Hebron, Barcelona, Spain; Medical School of Hannover, Hannover, Germany

    We previously developed a microarray-based test for antibody-mediated rejection (ABMR) in biopsies from renal transplants. To validate it, we undertook the INTERCOM study, a prospective…
  • 2013 American Transplant Congress

    Cytokine Measurement by High-Sensitivity Milliplex Assay in Cell Suspensions Obtained during Usual Kidney Allograft Biopsies

    N. Leca, S. Anderson, K. Muczynski

    Division of Nephrology, University of Washington, Seattle, WA

    PURPOSE: The purpose of the study was to determine if cytokines could be measured from the supernatant of kidney biopsy cell suspensions and if measured…
  • 2013 American Transplant Congress

    Alloantibody-Induced C4d Deposition, without Activation of Distal Complement Effectors C5a and C5b-9, Is Not Associated with Kidney Allograft Injury or Accommodation in Mice

    A. Chow, S. Husain, J. Pearcey, A. Raghuveer, T. Ho, P. Blanco, L. Zhu, B. Sis

    University of Alberta, Edmonton, Canada

    Complement split product C4d deposition in human organ transplants is a biomarker of classical complement activation triggered by antibody binding to donor antigens, but this…
  • 2013 American Transplant Congress

    Sitagliptin, DPP- IV Inhibitor, Protects Against Tacrolimus-Induced Diabetes in Rats

    L. Jin, S. Piao, K. Doh, S. Lim, S. Heo, B. Chung, C. Yang

    Convergent Research Consortium for Immunologic Disease, Seoul, Republic of Korea; Transplantation Research Center, Seoul, Republic of Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary&s Hospital, The Catholic University of Korea, Seoul, Republic of Korea; Nephrology & Dialysis Unit, Department of Internal Medicine, Affiliated Hospital, YanBian University Medical College, Jilin, China

    The pathogenesis of post-transplant diabetes mellitus is thought to be partly related to the direct toxic effect of tacrolimus on pancreas and the resultant decrease…
  • 2013 American Transplant Congress

    Splenic Artery Embolization in Liver Transplantation: A Single Center 5 Year Experience

    N. Presser, C. Tom, C. Quintini, Q. Liu, N. Ahmed, D. Kelly, K. Hashimoto, F. Aucejo, B. Eghtesad, C. Miller

    Liver Transplantation, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH; School of Medicine, Case Western Reserve University, Cleveland, OH

    Background:Severe portal hyperperfusion after liver transplantation has been shown to cause intrahepatic arterial vasoconstriction secondary to increased washout of adenosine (hepatic artery buffer response). Furthermore,…
  • 2013 American Transplant Congress

    Role of Estimated GFR CKD-EPI as Screening Tool for Donor Selection

    S. Fernandez, S. Mohan, Z. Zaky, J. Crew, G. Dube, J. Wexler, M. Carrol, L. Ratner, D. Cohen, B. Tanriover

    Nephrology, Columbia University Medical Center, New York, NY; Surgical Transplant Nephrology, Columbia University Medical Center, New York, NY

    Purpose: Living donor selection usually includes a measured renal function rather than estimated GFR (eGFR) equations, such as CKD-EPI because of concerns of accuracy. However,…
  • 2013 American Transplant Congress

    Tumor Necrosis Factor Receptor Type 2 Expression on Regulatory T Cells Predicts Acute Kidney Injury after Kidney Transplantation

    M. Nguyen, E. Fryml, S. Sahakian, S. Liu, J. Tchervenkov, S. Paraskevas

    Multi-Organ Transplant Program, McGill University Health Centre, Montreal, QC, Canada

    Background: Acute kidney injury (AKI) leads to worse graft outcomes after kidney transplantation. Tumor necrosis factor (TNF) is classically a mediator of AKI. Recent evidence,…
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